LIN-12/Notch Lateral Signaling (Caenorhabditis elegans)
From WikiPathways
Description
The LIN-12/Notch pathway plays two related roles in vulval development; to prevent adjacent induced vulval precursor cells (VPCs) from both becoming 1° VPCs and to induce VPCs adjacent to the 1°VPC to take a 2° cell fate.
See figure 14 in http://www.wormbook.org/chapters/www_vulvaldev/vulvaldev.pdf.
Quality Tags
Ontology Terms
Saving...Bibliography
- Yoo AS, Bais C, Greenwald I; ''Crosstalk between the EGFR and LIN-12/Notch pathways in C. elegans vulval development.''; Science, 2004 PubMed Europe PMC Scholia
- Sternberg PW; ''Vulval development.''; WormBook, 2005 PubMed Europe PMC Scholia
History
View all... |
External references
DataNodes
| View all... |
| Name | Type | Database reference | Comment |
|---|---|---|---|
| LET-23 | GeneProduct | ZK1067.1 (WormBase)  | |
| LET-60 | GeneProduct | ZK792.6 (WormBase) | |
| LIN-12 | GeneProduct | R107.8 (WormBase) | |
| MPK-1 | GeneProduct | F43C1.2 (WormBase) | |
| apm-1 | GeneProduct | F55A12.7 (WormBase) | |
| ark-1 | GeneProduct | C01C7.1 (WormBase) | |
| dpy-23 | GeneProduct | R160.1 (WormBase) | |
| gap-1 | GeneProduct | T24C12.2 (WormBase) | |
| lip-1 | GeneProduct | C05B10.1 (WormBase) | |
| lst-1 | GeneProduct | T22A3.3 (WormBase) | |
| lst-2 | GeneProduct | R160.7 (WormBase) | |
| lst-3 | GeneProduct | Y37A1B.1 (WormBase) | |
| lst-4 | GeneProduct | Y37A1B.2 (WormBase) | |
| sli-1 | GeneProduct | M02A10.3 (WormBase) | |
| unc-101 | GeneProduct | K11D2.3 (WormBase) |
Annotated Interactions
No annotated interactions
