Glutamate degradation IX (Saccharomyces cerevisiae)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none 2-OxoglutarateGDH2L-glutamateH2ONADNADHAmmoniaH+Name: Glutamate degradation IXOrganism: Saccharomyces cerevisiae


Description

In S. cerevisiae cells, the amino group of glutamate and the amide group of glutamine are the source of nitrogen for all other macromolecules. In order to provide ammonia for the synthesis of glutamine during growth on glutamate-yielding nitrogen sources, cells degrade glutamate into ammonia. The main pathway for S. cerevisiae glutamate degradation is catalyzed by the NAD dependent glutamate dehydrogenase (GDH2). Description adapted from on https://pathway.yeastgenome.org/.

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Quality Tags

Image:Curated.pngReview changes for Approved

Ontology Terms

Bibliography

  1. ''glutamate degradation IX''; Yeast Pathways,

History

View all...
CompareRevisionActionTimeUserComment
139618
Approved
view05:48, 24 June 2025EgonwWater with unicode
139616view05:46, 24 June 2025EgonwModified description
135947view05:23, 3 December 2024Khanspersupdate to mim-conversion, unify font
135505view17:27, 20 September 2024Khanspersupdated reference
135504view17:26, 20 September 2024Khanspersupdated reference
135503view17:25, 20 September 2024KhanspersOntology Term : 'classic metabolic pathway' added !
135502view17:25, 20 September 2024KhanspersOntology Term : 'glutamate degradation pathway IX' added !
135501view17:23, 20 September 2024KhanspersOntology Term : 'PW:0001382' removed !
135500view17:18, 20 September 2024KhanspersModified description
135499view17:14, 20 September 2024KhanspersModified title
134374view15:31, 21 July 2024EweitzRemove template comments
130537view19:44, 28 May 2024Khanspersremoved GenMAPP comments
130534view19:44, 28 May 2024KhanspersModified description
130531view19:43, 28 May 2024Khanspersremoved outdated content that was overlapping with other pathways
97401view09:45, 15 May 2018EgonwReplaced a secondary ChEBI identifier with a primary identifier.
97395view07:25, 14 May 2018EgonwReplaced a secondary ChEBI identifier with a primary identifier.
97387view04:36, 14 May 2018Khansperscleanup
97283view12:30, 7 May 2018MaxvansonConnected some unconnected arrows
97075view16:45, 26 April 2018MaxvansonConnected some unconnectd lines and changed several compounds to metabolites.
69932view19:58, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
69634view20:36, 8 July 2013MaintBotUpdated to 2013 gpml schema
67292view10:32, 26 June 2013Christine ChichesterOntology Term : 'glutamate degradation pathway III' added !
41870view04:52, 2 March 2011MaintBotRemoved redundant pathway information and comments
21736view11:32, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Glutamate Degradation III]] moved to [[Pathway:WP503]]: Moved to stable identifier
12718view07:59, 17 May 2008MaintBotautomated metabolite conversion
8738view14:08, 7 January 2008MaintBotAdded to category $category
8736view14:08, 7 January 2008J.HeckmanUploaded new pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
2-OxoglutarateMetaboliteCHEBI:30915 (ChEBI)
AmmoniaMetaboliteCHEBI:16134 (ChEBI)
GDH2GeneProductS000002374 (SGD)
H+MetaboliteHMDB59597 (HMDB)
H2OMetaboliteCHEBI:15377 (ChEBI)
L-glutamateMetabolite56-86-0 (CAS)
NADMetaboliteCHEBI:13389 (ChEBI)
NADHMetabolite53-84-9 (CAS)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP503"
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