Cholesterol pathway (Homo sapiens)
From WikiPathways
Description
This visualisation depicts the biosynthesis of cholesterol. Cholesterol is synthesis from it's precursor Acetyl-CoA through a multi-step process.
Quality Tags
Ontology Terms
Saving...Bibliography
- Porter FD; ''Malformation syndromes due to inborn errors of cholesterol synthesis.''; J Clin Invest, 2002 PubMed Europe PMC Scholia
History
External references
DataNodes
| View all... |
| Name | Type | Database reference | Comment |
|---|---|---|---|
| (S)-2,3-Epoxysqualene | Metabolite | Q27453274 (Wikidata)  | |
| 7-Dehydrocholesterol | Metabolite | 434-16-2 (CAS) | |
| Acetyl-CoA | Metabolite | 72-89-9 (CAS) | |
| CYP51A1 | GeneProduct | 1595 (Entrez Gene) | |
| Cholesterol | Metabolite | CHEBI:16113 (ChEBI) | |
| DHCR7 | GeneProduct | ENSG00000172893 (Ensembl) | |
| Dimethylallyl pyrophosphate | Metabolite | 358-72-5 (CAS) | |
| FDFT1 | GeneProduct | 2222 (Entrez Gene) | |
| FDPS | GeneProduct | 2224 (Entrez Gene) | |
| Geranyl-PP | Metabolite | 6699-20-3 (CAS) | |
| HMG-CoA | Metabolite | HMDB0001375 (HMDB) | |
| HMGCR | GeneProduct | 3156 (Entrez Gene) | |
| HMGCS1 | GeneProduct | 3157 (Entrez Gene) | |
| IDI1 | GeneProduct | 3422 (Entrez Gene) | |
| LSS | GeneProduct | 4047 (Entrez Gene) | |
| Lanosterin | Metabolite | 79-63-0 (CAS) | |
| Lathosterol | Metabolite | 80-99-9 (CAS) | |
| MSMO1 | GeneProduct | 6307 (Entrez Gene) | |
| MVD | GeneProduct | 4597 (Entrez Gene) | |
| MVK | GeneProduct | 4598 (Entrez Gene) | |
| Mevalonic acid 5-pyrophosphate | Metabolite | 1492-08-6 (CAS) | |
| Mevalonic acid-5P | Metabolite | 73566-35-5 (CAS) | |
| Mevalonic acid | Metabolite | 150-97-0 (CAS) | |
| NSDHL | GeneProduct | 50814 (Entrez Gene) | NAD(P) dependent steroid dehydrogenase-like |
| PMVK | GeneProduct | 10654 (Entrez Gene) | |
| SC5DL | GeneProduct | 6309 (Entrez Gene) | |
| SQLE | GeneProduct | 6713 (Entrez Gene) | |
| Squalene | Metabolite | 111-02-4 (CAS) | |
| farnesyl pyrophosphate | Metabolite | 13058-04-3 (CAS) | |
| isopentenyl pyrophosphate | Metabolite | 358-71-4 (CAS) |
Annotated Interactions
No annotated interactions
