Multiple sclerosis mechanism and therapies (Homo sapiens)

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Revision as of 11:32, 10 May 2025 by Eweitz (Talk | contribs)
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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none PeripheryCladribineTeriflunomideInterferon-betaAlemtuzumabEvobrutinibTolebrutinibOfatumumabTolebrutinibCladribineOcrelizumabRituximabAlemtuzumabDimethylfumarateDiroximelfumarateFingolimodSiponimodOzanimodPonesimodGlatiramer acetateTolebrutinibNatalizumabInterferon-betaB cellT cellT cellAPCB cellAPCCD8+cellMacrophageMacrophageT cellMacrophageAPCTh17cellTh 1cellT cellOligodendrocyteNeuronCirculationBlood-brain barrierCentral nervous systemB cellMacrophageB cellMS4A1SiponimodS1PR5CD52ITGA4ITGB1B cellName: Multiple sclerosis mechanism and therapiesOrganism: Homo sapiens


Description

No description

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Quality Tags

Ontology Terms

Pathway Ontology : citric acid cycle pathway
 

Bibliography

  1. Bierhansl L, Hartung HP, Aktas O, Ruck T, Roden M, Meuth SG; ''Thinking outside the box: non-canonical targets in multiple sclerosis.''; Nat Rev Drug Discov, 2022 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
139164view12:24, 24 May 2025EweitzTrigger SVG regeneration without redundant metadata
139067view07:05, 18 May 2025EgonwAdded a missing datasource
139009view21:04, 10 May 2025EweitzStraighten lines, for clarity
139004view20:05, 10 May 2025EweitzOntology Term : 'multiple sclerosis' added !
139003view20:04, 10 May 2025EweitzOntology Term : 'neuron' added !
139002view20:04, 10 May 2025EweitzOntology Term : 'oligodendrocyte' added !
139001view20:04, 10 May 2025EweitzOntology Term : 'macrophage' added !
139000view20:03, 10 May 2025EweitzOntology Term : 'lymphocyte' added !
138999view20:03, 10 May 2025EweitzOntology Term : 'T-helper 1 cell' added !
138998view20:03, 10 May 2025EweitzOntology Term : 'T-helper 17 cell' added !
138997view20:03, 10 May 2025EweitzOntology Term : 'CD8-positive, alpha-beta T cell' added !
138996view20:02, 10 May 2025EweitzOntology Term : 'professional antigen presenting cell' added !
138995view20:01, 10 May 2025EweitzOntology Term : 'T cell' added !
138994view19:58, 10 May 2025EweitzOntology Term : 'B cell' added !
138993view19:54, 10 May 2025EweitzModified description
138992view19:49, 10 May 2025EweitzModified description
138991view19:45, 10 May 2025EweitzModified description
138990view19:43, 10 May 2025EweitzAdd identifiers for drugs
138989view19:05, 10 May 2025EweitzAdd identifiers to genes
138988view18:37, 10 May 2025EweitzRefine graphics
138987view18:35, 10 May 2025EweitzEconomize layout
138986view18:34, 10 May 2025EweitzAbut endothelial cells
138985view18:29, 10 May 2025EweitzAdd interactions for natalizumab
138984view18:12, 10 May 2025EweitzAlign dashes
138983view18:11, 10 May 2025EweitzAlign dashes
138982view18:02, 10 May 2025EweitzModified description
138981view17:59, 10 May 2025EweitzFix PathVisio / Kaavio graphical discrepancy
138980view17:57, 10 May 2025EweitzFix PathVisio / Kaavio graphical discrepancy
138979view17:56, 10 May 2025EweitzAdd literature reference
138978view17:54, 10 May 2025EweitzPolish graphics
138977view17:04, 10 May 2025EweitzAdd neo-follicles
138976view16:40, 10 May 2025EweitzRefine graphics
138975view16:36, 10 May 2025EweitzRefine graphics
138974view16:24, 10 May 2025EweitzEconomize layout
138973view16:10, 10 May 2025EweitzAdd interactions in BBB / CNS
138972view15:34, 10 May 2025EweitzAdd interferon-beta interaction, refine explainer text
138971view15:21, 10 May 2025EweitzAdd ingress; interaction for glatimer acetate
138970view15:04, 10 May 2025EweitzAdd interactions
138969view14:38, 10 May 2025EweitzAdd interactions, label lymph node
138968view13:31, 10 May 2025EweitzAdd lymphocyte, S1PR, related interactions
138967view11:32, 10 May 2025EweitzAdd lymph node fill color
138966view11:27, 10 May 2025EweitzAdd more lymph vessels
138965view11:19, 10 May 2025EweitzAdd lymph vessel to lymph node
138964view11:07, 10 May 2025EweitzAdd interaction, complex
138963view01:08, 10 May 2025EweitzAdd interactions, gene nodes
138955view11:47, 9 May 2025EweitzAdd interactions, gene
138954view11:14, 9 May 2025EweitzAdd blood-brain barrier graphics
138952view12:04, 8 May 2025EweitzRefine graphics in connection between myelin and oligodendrocyte
138951view11:59, 8 May 2025EweitzAdd tissue labels, enhance graphics
138950view11:43, 8 May 2025EweitzFix PathVisio / Kaavio graphical discrepancy

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
AlemtuzumabMetabolite
CD52GeneProduct
CladribineMetabolite
Dimethyl fumarateMetabolite
Diroximel fumarateMetabolite
EvobrutinibMetabolite
FingolimodMetabolite
Glatiramer acetateMetabolite
ITGA4GeneProduct
ITGB1GeneProduct
Interferon-betaMetabolite
MS4A1GeneProduct
NatalizumabMetabolite
OcrelizumabMetabolite
OfatumumabMetabolite
OzanimodMetabolite
PonesimodMetabolite
RituximabMetabolite
S1PR5GeneProduct
SiponimodMetabolite
TeriflunomideMetabolite
TolebrutinibMetabolite

Annotated Interactions

No annotated interactions

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