Glutamate degradation I (Saccharomyces cerevisiae)

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Description

In S. cerevisiae, the main pathway for glutamate degradation is catalyzed by the glutamate dehydrogenase encoded by GDH2 (https://www.wikipathways.org/pathways/WP503.html). However, glutamate can also by degraded into gamma-aminobutyrate (GABA) by the glutamate decarboxylase Gad1p and then converted into succinate by the enzymes encoded by UGA1 and UGA2. Based on Yeast Pathways https://pathway.yeastgenome.org/.

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Quality Tags

Ontology Terms

 

Bibliography

  1. ''glutamate degradation I''; Yeast Pathways,

History

View all...
CompareRevisionActionTimeUserComment
140475view06:04, 29 August 2025EgonwMore unicode
139598view05:24, 23 June 2025EgonwModified description
139596view05:22, 23 June 2025EgonwWater with unicode
135508view18:41, 20 September 2024KhanspersModified description
135507view18:40, 20 September 2024Khanspersupdated reference
135506view18:39, 20 September 2024Khanspersupdate with info from Yeast Pathways
130527view19:36, 28 May 2024Khanspersadded biocyc reference
130526view19:35, 28 May 2024KhanspersOntology Term : 'glutamate degradation pathway I' added !
130525view19:34, 28 May 2024KhanspersModified description
130524view19:32, 28 May 2024KhanspersOntology Term : 'PW:0001380' removed !
130523view19:32, 28 May 2024KhanspersModified description
130522view19:31, 28 May 2024KhanspersReverted to version '19:20, 28 May 2024' by Khanspers
130521view19:30, 28 May 2024KhanspersModified description
130520view19:20, 28 May 2024Khanspersremoved irrelevant part
97054view15:17, 26 April 2018TimverbruggenConnected lines
89710view08:44, 27 September 2016EgonwReplace the CAS number of the salt with that of just the metabolite.
69958view20:53, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
69610view20:33, 8 July 2013MaintBotUpdated to 2013 gpml schema
67291view10:32, 26 June 2013Christine ChichesterOntology Term : 'glutamate degradation pathway I' added !
44765view03:02, 2 October 2011AlexanderPico
44764view03:00, 2 October 2011AlexanderPico
44763view02:59, 2 October 2011AlexanderPico
44760view02:54, 2 October 2011AlexanderPicoUndo revision 44759 by [[Special:Contributions/AlexanderPico|AlexanderPico]] ([[User talk:AlexanderPico|Talk]])
44759view02:53, 2 October 2011AlexanderPico
41842view04:50, 2 March 2011MaintBotRemoved redundant pathway information and comments
21850view11:32, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Glutamate Degradation I]] moved to [[Pathway:WP556]]: Moved to stable identifier
12716view07:59, 17 May 2008MaintBotautomated metabolite conversion
8735view14:08, 7 January 2008MaintBotAdded to category $category
8733view14:08, 7 January 2008J.HeckmanUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2-oxoglutarateMetabolite16810 (ChEBI)
4-aminobutanoateMetaboliteCHEBI:59888 (ChEBI)
CO2MetaboliteHMDB01967 (HMDB)
GAD1GeneProductS000004862 (SGD)
H+MetaboliteHMDB59597 (HMDB)
H₂OMetabolite15377 (ChEBI)
L-glutamateMetabolite29985 (ChEBI)
L-glutamateMetaboliteCHEBI:29985 (ChEBI)
NAD(P)+Metabolite13390 (ChEBI)
NAD(P)HMetabolite13392 (ChEBI)
UGA1GeneProductYGR019W (Ensembl)
UGA2GeneProductYBR006W (Ensembl)
succinate semialdehydeMetabolite57706 (ChEBI)
succinateMetabolite30031 (ChEBI)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP556"