2-phenylethanol biosynthesis (Saccharomyces cerevisiae)

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Description

Metabolic pathway of 2-Phenylethanol production in microorganisms.

Wild-Type Saccharomyces cerevisiae is capable of producing 2-PE through both the shikimate and Ehrlich metabolic routes. This was created with reference to the following figure.

[figure](tileshop_pmc_inline.html?title=Click%20on%20image%20to%20zoom&p=PMC3&id=12294199_foods-14-02444-g001.jpg)

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Bibliography

  1. Zhang C, Fan T, Wang Z, Yu J, Guo X, Jiang W, Miao L, Yang H; ''Screening of High-Yield 2-Phenylethanol Producing Strain from Wild-Type Saccharomyces cerevisiae and Optimizationof Fermentation Parameters.''; Foods, 2025 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
140614view06:05, 18 September 2025FujitaModify the start line type of the interaction between phenylpyruvate and phenylalanine.
140599view02:56, 17 September 2025FujitaUndo revision 140598 by [[Special:Contributions/Fujita|Fujita]] ([[User talk:Fujita|Talk]])
140598view02:54, 17 September 2025FujitaReverted to version '01:31, 17 September 2025' by Fujita
140595view01:37, 17 September 2025FujitaModified description
140593view01:31, 17 September 2025FujitaNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
2-phenylethanolMetaboliteCHEBI:49000 (ChEBI)
3-Deoxy-D-arabino- heptulosonic acid 7-phosphateMetaboliteCHEBI:18150 (ChEBI)
ADH2GeneProductYMR303C (Ensembl)
ARO10GeneProductYDR380W (Ensembl)
ARO1GeneProductYDR127W (Ensembl)
ARO3GeneProductYDR035W (Ensembl)
ARO4GeneProductYBR249C (Ensembl)
ARO7GeneProductYPR060C (Ensembl)
ARO8GeneProductYGL202W (Ensembl)
ARO9GeneProductYHR137W (Ensembl)
Ehrlich pathwayPathway
Glucose 6-phosphateMetaboliteHMDB01401 (HMDB)
GlucoseMetaboliteCHEBI:4167 (ChEBI)
PHA2GeneProductYNL316C (Ensembl)
PhenylacetaldehydeMetaboliteHMDB06236 (HMDB)
PrephenateMetaboliteHMDB12283 (HMDB)
Shikimate pathwayPathway
ShikimateMetaboliteCHEBI:16119 (ChEBI)
TDH3GeneProductYGR192C (Ensembl)
ZWF1GeneProductYNL241C (Ensembl)
chorismateMetaboliteCHEBI:29748 (ChEBI)
erythose-4-phosphateMetaboliteCHEBI:48153 (ChEBI)
phenylalanineMetaboliteCHEBI:58095 (ChEBI)
phenylpyruvateMetabolite
phosphoenolpyruvateMetaboliteCHEBI:58702 (ChEBI)

Annotated Interactions

No annotated interactions

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