Caffeine synthesis (Citrus sinensis)

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Description

Citrus sinensis caffeine synthesis

This is the caffeine synthesis pathway for Citrus sinensis, but since Citrus sinensis is not listed in the organism field, it is registered under Arabidopsis thaliana.

[Convergent Biochemical Pathways for Xanthine Alkaloid Production in Plants Evolved from Ancestral Enzymes with Different Catalytic Properties](https://pmc.ncbi.nlm.nih.gov/articles/PMC8233510/)

[Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes](https://pmc.ncbi.nlm.nih.gov/articles/PMC5035902/)

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Ontology Terms

 

Bibliography

  1. O'Donnell AJ, Huang R, Barboline JJ, Barkman TJ; ''Convergent Biochemical Pathways for Xanthine Alkaloid Production in Plants Evolved from Ancestral Enzymes with Different Catalytic Properties.''; Mol Biol Evol, 2021 PubMed Europe PMC Scholia
  2. Huang R, O'Donnell AJ, Barboline JJ, Barkman TJ; ''Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes.''; Proc Natl Acad Sci U S A, 2016 PubMed Europe PMC Scholia
  3. Wright GA, Baker DD, Palmer MJ, Stabler D, Mustard JA, Power EF, Borland AM, Stevenson PC; ''Caffeine in floral nectar enhances a pollinator's memory of reward.''; Science, 2013 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
141384view14:14, 11 November 2025EweitzModified title
140939view11:51, 30 October 2025EweitzEconomize layout
140938view11:50, 30 October 2025EweitzEconomize layout
140749view06:45, 20 October 2025EgonwAdded a 2013 reference with caffeine concentrations
140739view10:15, 18 October 2025EgonwAdded metabolite IDs
140738view10:07, 18 October 2025EgonwOntology Term : 'classic metabolic pathway' added !
140610view09:47, 17 September 2025MaintBotSpecies updated
140596view01:44, 17 September 2025HayashiNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1-methylxanthineMetabolite
3-methylxanthineMetabolite
CisXMT1GeneProduct
CisXMT2GeneProduct
TheophyllineMetabolite
XanthinMetabolite
caffeineMetabolite

Annotated Interactions

No annotated interactions

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