B cell receptor signaling pathway (Canis familiaris)

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DCY->NUENRecruitmentCY->PMNUCY->PMGOCY->PMDCY->NUMitochondriaDeubiquitinationReaction through unknown mechanisms/moleculesDCY->NUCY->PMCY->PMMolecular associationExtracellularDemethylationERPMCY->NUControlAutophosphorylationMTECDCY->PMPalmitoylationLigandCY->PMDCY->PMMolecule in the pathwayCytoplasmPM->CYCY->PMDGolgi apparatusDUbiquitinationMethylationCY->NUDMACY->PMAcetylationDDCY->PMNU->CYDDCY->NUDesumoylationMT->CYEndoplasmic reticulumCY->PM(Protein-protein interaction)DNucleusActivationPhosphorylationPM->CYCYAccesion Number: NetPath 12SumoylationCY->PMARP2/3ComplexProteolytic cleavageDCY->NUCY->PMProteins in a complex interactionGlycosylationEnzyme ComplexDCY->MTCY->PMDeacetylationDCY->NUCY->PMCY->PMNU->CYPlasma membraneDephosphorylationInhibitionEndosomeTranslocationCY->PMReceptorPIP4K2AGTF2IINPP5DPIK3R2ITPR1ATF2CHUKFYNARPC2NFATC1CARD11DOK1PLEKHA1IKBKBCMTM3CYCSLIME1RHOAPRKCBLAT2ITPR2CD79APRKCEPTPN11PPP3R1CD22RASGRP3CD81CASP9NFATC3ACTR3PRKCBCCND2PDPK1CTNNB1PTK2BSTAT1NFATC2CD19MAP3K7SOS1RPS6LOC490941MAPK3PPP3CAELK1ITKDAPP1MAPK1HCKSYKCBLBBCL10PRKCQDUSP4BCL6CARD11LCKCREB1LOC486589PLEKHA2BLNKPTPRCPTPN6MAP4K1CR2PIK3AP1PIK3AP1RELGRB2ARPC5RASGRP3GSK3AGAB1CDK2PRKD1RB1CDK7NFATC3CHST15IGHMRPS6KA1AKT1HNRNPKMAPKAPK2MAPK8CRKLBLKPIK3CGRPS6KB1PIP4K2CZAP70NFATC2BAXCD79BHCLS1PRKCEFCGR2BRELAGTF2IBTKIKBKBPTPN6STAT3SYKRELALAT2RAPGEF1PIP5K1APTK2TECHCLS1VAV2NFKBIACDK4CYCSHCLS1CD72LYNGAB1JUNCSKCBLCASP7CD5BAXVAV1PIP5K1BCCNA2CD79ASH3BP2AKT1PIP5K1CMAP2K1PIP4K2BRASA1PLEKHA1STAP1NCK1PIP4K2BDOK3PILRBFOXO1LOC490941ACTR2PIP5K1BDUSP6CHUKPLCG2SHC1BRAFSYKPRKCDPLCG1BCL2L11BCL2WASPLCG2CDK6PTPN6SLA2BLNKRAF1BCAR1RAP2ACTNNB1SHC1PPP3CBGene SymbolLOC486589CRKPLEKHA2ATP2B4GAB2PDK2BTKGRB2PIP4K2BRELCRKIKBKGLYNARPC4CCND3LCP2LYNDAPP1SOS2PIP5K1BARPC1BBANK1RAPGEF1PTPN18GSK3BCCNE1INPP5DNEDD9MAPK4RPS6KA1PRKCDARPC3MAP2K2MAPK14SH2B2PIK3R1


Description

No description

Comments

GenMAPP notes 
NetPath 12 - B Cell Receptor Signaling pathway. NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP23(r20725) with a 90% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
118019view11:36, 23 May 2021EweitzModified title
89909view13:24, 6 October 2016MkutmonModified description
73855view00:56, 26 February 2014MaintBotupdated schema
67069view10:02, 26 June 2013Christine ChichesterOntology Term : 'B cell receptor signaling pathway' added !
40714view21:52, 1 March 2011MaintBotRemoved redundant pathway information and comments
35707view23:14, 12 February 2010AlexanderPico
33993view18:36, 9 December 2009MaintBotAutomatic update of empty xrefs
31269view19:58, 13 August 2009MaintBotFixed text labels
30713view22:53, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACTR2GeneProduct481396 (Entrez Gene)
ACTR3GeneProduct403702 (Entrez Gene)
AKT1GeneProduct490878 (Entrez Gene)
ARPC1BGeneProduct479744 (Entrez Gene)
ARPC2GeneProduct478907 (Entrez Gene)
ARPC3GeneProduct477474 (Entrez Gene)
ARPC4GeneProduct476540 (Entrez Gene)
ARPC5GeneProduct480037 (Entrez Gene)
ATF2GeneProduct478806 (Entrez Gene)
ATP2B4GeneProduct403731 (Entrez Gene)
BANK1GeneProduct487881 (Entrez Gene)
BAXGeneProduct403523 (Entrez Gene)
BCAR1GeneProduct479648 (Entrez Gene)
BCL10GeneProduct490183 (Entrez Gene)
BCL2GeneProduct403416 (Entrez Gene)
BCL2L11GeneProduct612867 (Entrez Gene)
BCL6GeneProduct488124 (Entrez Gene)
BLKGeneProduct486080 (Entrez Gene)
BLNKGeneProduct486814 (Entrez Gene)
BRAFGeneProduct475526 (Entrez Gene)
BTKGeneProduct492019 (Entrez Gene)
CARD11GeneProduct489887 (Entrez Gene)
CASP7GeneProduct486896 (Entrez Gene)
CASP9GeneProduct487432 (Entrez Gene)
CBLGeneProduct
CBLBGeneProduct487965 (Entrez Gene)
CCNA2GeneProduct483845 (Entrez Gene)
CCND2GeneProduct611782 (Entrez Gene)
CCND3GeneProduct608847 (Entrez Gene)
CCNE1GeneProduct484610 (Entrez Gene)
CD19GeneProduct607898 (Entrez Gene)
CD22GeneProduct476485 (Entrez Gene)
CD5GeneProduct612338 (Entrez Gene)
CD72GeneProduct481595 (Entrez Gene)
CD79AGeneProduct484483 (Entrez Gene)
CD79BGeneProduct609449 (Entrez Gene)
CD81GeneProduct611606 (Entrez Gene)
CDK2GeneProduct606931 (Entrez Gene)
CDK4GeneProduct481131 (Entrez Gene)
CDK6GeneProduct609920 (Entrez Gene)
CDK7GeneProduct608441 (Entrez Gene)
CHST15GeneProduct486928 (Entrez Gene)
CHUKGeneProduct477796 (Entrez Gene)
CMTM3GeneProduct
CR2GeneProduct490269 (Entrez Gene)
CREB1GeneProduct607922 (Entrez Gene)
CRKGeneProduct
CRKLGeneProduct608125 (Entrez Gene)
CSKGeneProduct487649 (Entrez Gene)
CTNNB1GeneProduct477032 (Entrez Gene)
CYCSGeneProduct475258 (Entrez Gene)
DAPP1GeneProduct478491 (Entrez Gene)
DOK1GeneProduct483100 (Entrez Gene)
DOK3GeneProduct489087 (Entrez Gene)
DUSP4GeneProduct482880 (Entrez Gene)
DUSP6GeneProduct482594 (Entrez Gene)
ELK1GeneProduct491860 (Entrez Gene)
FCGR2BGeneProduct
FOXO1GeneProduct477295 (Entrez Gene)
FYNGeneProduct475032 (Entrez Gene)
GAB1GeneProduct483808 (Entrez Gene)
GAB2GeneProduct485167 (Entrez Gene)
GRB2GeneProduct483312 (Entrez Gene)
GSK3AGeneProduct484476 (Entrez Gene)
GSK3BGeneProduct478575 (Entrez Gene)
GTF2IGeneProduct479714 (Entrez Gene)
Gene SymbolGeneProduct
HCKGeneProduct485828 (Entrez Gene)
HCLS1GeneProduct
HNRNPKGeneProduct480979 (Entrez Gene)
IGHMGeneProduct
IKBKBGeneProduct482839 (Entrez Gene)
IKBKGGeneProduct
INPP5DGeneProduct
ITKGeneProduct489159 (Entrez Gene)
ITPR1GeneProduct476548 (Entrez Gene)
ITPR2GeneProduct486628 (Entrez Gene)
JUNGeneProduct609429 (Entrez Gene)
LAT2GeneProduct607740 (Entrez Gene)
LCKGeneProduct478151 (Entrez Gene)
LCP2GeneProduct489126 (Entrez Gene)
LIME1GeneProduct
LOC486589GeneProduct486589 (Entrez Gene)
LOC490941GeneProduct490941 (Entrez Gene)
LYNGeneProduct477886 (Entrez Gene)
MAP2K1GeneProduct478347 (Entrez Gene)
MAP2K2GeneProduct611939 (Entrez Gene)
MAP3K7GeneProduct
MAP4K1GeneProduct484527 (Entrez Gene)
MAPK14GeneProduct403856 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
MAPK4GeneProduct491690 (Entrez Gene)
MAPK8GeneProduct477746 (Entrez Gene)
MAPKAPK2GeneProduct490263 (Entrez Gene)
NCK1GeneProduct485677 (Entrez Gene)
NEDD9GeneProduct488220 (Entrez Gene)
NFATC1GeneProduct483925 (Entrez Gene)
NFATC2GeneProduct485930 (Entrez Gene)
NFATC3GeneProduct479678 (Entrez Gene)
NFKBIAGeneProduct480291 (Entrez Gene)
PDK2GeneProduct491075 (Entrez Gene)
PDPK1GeneProduct479875 (Entrez Gene)
PIK3AP1GeneProduct608653 (Entrez Gene)
PIK3CGGeneProduct483266 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PIK3R2GeneProduct609956 (Entrez Gene)
PILRBGeneProduct
PIP4K2AGeneProduct608414 (Entrez Gene)
PIP4K2BGeneProduct491034 (Entrez Gene)
PIP4K2CGeneProduct474417 (Entrez Gene)
PIP5K1AGeneProduct
PIP5K1BGeneProduct476331 (Entrez Gene)
PIP5K1CGeneProduct485054 (Entrez Gene)
PLCG1GeneProduct485874 (Entrez Gene)
PLCG2GeneProduct489692 (Entrez Gene)
PLEKHA1GeneProduct477851 (Entrez Gene)
PLEKHA2GeneProduct482851 (Entrez Gene)
PPP3CAGeneProduct403486 (Entrez Gene)
PPP3CBGeneProduct479248 (Entrez Gene)
PPP3R1GeneProduct612559 (Entrez Gene)
PRKCBGeneProduct489968 (Entrez Gene)
PRKCDGeneProduct494005 (Entrez Gene)
PRKCEGeneProduct609934 (Entrez Gene)
PRKCQGeneProduct478013 (Entrez Gene)
PRKD1GeneProduct609091 (Entrez Gene)
PTK2GeneProduct475108 (Entrez Gene)
PTK2BGeneProduct486102 (Entrez Gene)
PTPN11GeneProduct477488 (Entrez Gene)
PTPN18GeneProduct
PTPN6GeneProduct486717 (Entrez Gene)
PTPRCGeneProduct490255 (Entrez Gene)
RAF1GeneProduct484648 (Entrez Gene)
RAP2AGeneProduct476968 (Entrez Gene)
RAPGEF1GeneProduct491286 (Entrez Gene)
RASA1GeneProduct479158 (Entrez Gene)
RASGRP3GeneProduct611329 (Entrez Gene)
RB1GeneProduct476915 (Entrez Gene)
RELGeneProduct474606 (Entrez Gene)
RELAGeneProduct483729 (Entrez Gene)
RHOAGeneProduct403954 (Entrez Gene)
RPS6GeneProduct474722 (Entrez Gene)
RPS6KA1GeneProduct487353 (Entrez Gene)
RPS6KB1GeneProduct480580 (Entrez Gene)
SH2B2GeneProduct489820 (Entrez Gene)
SH3BP2GeneProduct488797 (Entrez Gene)
SHC1GeneProduct490439 (Entrez Gene)
SLA2GeneProduct485859 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene)
SOS2GeneProduct490682 (Entrez Gene)
STAP1GeneProduct482171 (Entrez Gene)
STAT1GeneProduct488449 (Entrez Gene)
STAT3GeneProduct490967 (Entrez Gene)
SYKGeneProduct484196 (Entrez Gene)
TECGeneProduct482140 (Entrez Gene)
VAV1GeneProduct485016 (Entrez Gene)
VAV2GeneProduct608060 (Entrez Gene)
WASGeneProduct491867 (Entrez Gene)
ZAP70GeneProduct

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1144"
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