Metapathway biotransformation (Bos taurus)

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ReductionHydrolysisOxidationEpoxide hydrolasesAmino acid conjugationMethyltransferasesMethylationAmino acid acyl transferasesGlutathione conjugationElectrophilesSulfotransferasesCytochrome P450NucleophilesFlavin monooxygenasesSulfationAldo-keto reductasesGlucuronosyltransferasesGlutathione peroxidasesAcetylationGlucuronidationN-acetyltransferasesGlutathione synthetaseGlutathione reductaseGlutathione transferasesCYP27B1IPI00705153.2NP_001029801.1A9CSS1_BOVINIPI00688083.3MethyltransferaseCYP2C9A6QPJ8_BOVINST1A1_BOVINSubstrate-AaNP_001071381.1IPI00701497.5IPI00726067.3GSTA1CYP450CYP2D6IPI00688142.3NP_001040025.1IPI00697335.1NP_001069607.1ST1E1_BOVINNP_001073084.1IPI00686912.3NP_777187.1NP_001092408.1HS3ST3A1NP_001094774.1IPI00905203.2CYP2A13UGT1A10NP_001096716.1SULT2B1XR_027890.2CYP3A4CYP2A7LOC515352Flavin monooxygenaseSubstrate-OHGlutathione transferaseUGT1A4CHST8NP_001069613.1IPI00693008.2CP2E1_BOVINGlucuronosyltransferaseIPI00713683.4UGT1A9Substrate-SO3HGSTA4_BOVINKCAB2_BOVINCYP2C18NP_001095549.1ST1B1_BOVINGPX1_BOVINNP_001069590.1Substrate-SHIPI00709378.3AK1A1_BOVINSubstrate-CH3GSTP1_BOVINGPX3_BOVINSulfotransferaseNP_001029545.1GSTM1NP_001091500.1GPX4_BOVINGSTM5ST1A1_BOVINUGT2B28ARY1_BOVINA6H748_BOVINSULT2A1CYP19A1UGT2A1IPI00710606.2NP_001020506.1UGT1A1GSTA5CYP17A1GSTM4Q95KN3_BOVINSubstrate-GlAKR7A3CP2U1_BOVINIPI00693768.3CYP2C19Xenobiotic substrateIPI00709424.4CYP4F11IPI00699039.4AKR1C4ST1A1_BOVINCP11A_BOVINIPI00716297.1UGT2B7NP_001069154.1Amino acid acyltransferaseCYP2F1COMT_BOVINIPI00693008.2GSHB_BOVINNP_001075096.1GSTO1GSTA2AKR1C2IPI00906116.1IPI00705496.1CP51A_BOVINCYP4F8UGT1A3UGT2B4KCAB1_BOVINUGT2B17CHST14NAT14_BOVINMGST2_BOVINGSTM2HS6ST2CYP3A5MGST1_BOVINIPI00695153.3CYP3A43CYP4F2CYP46A1HNMT_BOVINGSTCD_BOVINUGT2B15Substrate-SGNNMTUGT1A5IPI00695412.4AKR7A2IPI00694081.4GSTT2BARY1_BOVINNP_001069002.1ST1A1_BOVINSULT1C4NP_001092474.1IPI00700522.1CYP2A6NDST2_BOVINCYP11B2IPI00698855.3IPI00904186.1NP_001069683.1NP_001092414.1LOC614317IPI00708458.2CHST9CYP4Z1AKR1C3NP_001077117.1GSTT2CYP11B1UGT2A2G3ST3_BOVINSubstrate-AcSubstrate=OGSTA3UGT1A6IPI00692810.3AKR1B1NAT13_BOVINNP_001069670.1NP_001069735.1CYP2C8HS3ST4CYP2J2SULT1C2CYP4F12NP_001068630.1IPI00704129.5NP_001069986.1N-acetyltransferaseNP_001076882.1TPMT_BOVINSubstrate-NH2FMO3IPI00702562.3UGT2B11HS3ST3B1UGT1A7CYP21A2NAT8IPI00716958.3GLYATL1NP_001091480.1IPI00698655.1IPI00906608.1G3ST1_BOVINNM_001075173.1GLYATCYP3A7Aldo-keto reductaseGPX2IPI00903985.1NP_001093836.1AKR1C1CYP4F22IPI00689284.1G3ST4_BOVINNP_001071429.1GSTT1CP20A_BOVINMGST3_BOVINNP_001095558.1IPI00687876.3Substrate-O-R


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP702(r29945) with a 58% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
80841view15:28, 30 June 2015Mkutmonhomology conversion
70171view00:39, 13 July 2013AlexanderPicoModified title
63459view17:18, 10 May 2013MaintBotUpdated to 2013 gpml schema
58827view23:19, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
53460view18:40, 7 November 2012AndraAdded missing Entrez Gene Id's after RDF Tidy
40594view19:33, 1 March 2011MaintBotRemoved redundant pathway information and comments
33831view00:29, 9 December 2009MaintBotAutomatic update of empty xrefs
33196view18:19, 5 November 2009KhanspersModified categories
32487view12:45, 17 August 2009MaintBotFixed text labels
32182view12:32, 15 August 2009MaintBotFixed text labels
31652view11:37, 14 August 2009MaintBotFixed group labels
31185view19:28, 13 August 2009MaintBotFixed text labels
30575view22:07, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A6H748_BOVINGeneProductENSBTAG00000000085 (Ensembl Cow)
A6QPJ8_BOVINGeneProductENSBTAG00000021118 (Ensembl Cow)
A9CSS1_BOVINGeneProductENSBTAG00000010531 (Ensembl Cow)
AK1A1_BOVINGeneProductENSBTAG00000000497 (Ensembl Cow)
AKR1B1GeneProduct
AKR1C1GeneProduct
AKR1C2GeneProduct
AKR1C3GeneProduct
AKR1C4GeneProduct
AKR7A2GeneProduct
AKR7A3GeneProduct
ARY1_BOVINGeneProductENSBTAG00000016473 (Ensembl Cow)
Aldo-keto reductaseGeneProduct
Amino acid acyltransferaseGeneProduct
CHST14GeneProduct511245 (Entrez Gene)
CHST8GeneProduct
CHST9GeneProduct525909 (Entrez Gene)
COMT_BOVINGeneProductENSBTAG00000019516 (Ensembl Cow)
CP11A_BOVINGeneProductENSBTAG00000006934 (Ensembl Cow)
CP20A_BOVINGeneProductENSBTAG00000000851 (Ensembl Cow)
CP2E1_BOVINGeneProductENSBTAG00000018365 (Ensembl Cow)
CP2U1_BOVINGeneProductENSBTAG00000012972 (Ensembl Cow)
CP51A_BOVINGeneProductENSBTAG00000001992 (Ensembl Cow)
CYP11B1GeneProduct
CYP11B2GeneProduct
CYP17A1GeneProduct
CYP19A1GeneProduct
CYP21A2GeneProduct282425 (Entrez Gene)
CYP27B1GeneProductENSBTAG00000016906 (Ensembl Cow)
CYP2A13GeneProduct
CYP2A6GeneProduct
CYP2A7GeneProduct
CYP2C18GeneProduct
CYP2C19GeneProduct
CYP2C8GeneProduct
CYP2C9GeneProduct
CYP2D6GeneProduct
CYP2F1GeneProduct
CYP2J2GeneProduct
CYP3A4GeneProduct
CYP3A43GeneProduct
CYP3A5GeneProduct
CYP3A7GeneProduct
CYP450GeneProduct
CYP46A1GeneProduct
CYP4F11GeneProduct
CYP4F12GeneProduct
CYP4F2GeneProduct
CYP4F22GeneProduct
CYP4F8GeneProduct
CYP4Z1GeneProduct
FMO3GeneProduct
Flavin monooxygenaseGeneProduct
G3ST1_BOVINGeneProductENSBTAG00000014232 (Ensembl Cow)
G3ST3_BOVINGeneProductENSBTAG00000002772 (Ensembl Cow)
G3ST4_BOVINGeneProductENSBTAG00000015017 (Ensembl Cow)
GLYATGeneProduct
GLYATL1GeneProduct
GPX1_BOVINGeneProductENSBTAG00000004274 (Ensembl Cow)
GPX2GeneProduct
GPX3_BOVINGeneProductENSBTAG00000043553 (Ensembl Cow)
GPX4_BOVINGeneProductENSBTAG00000020778 (Ensembl Cow)
GSHB_BOVINGeneProductENSBTAG00000003504 (Ensembl Cow)
GSTA1GeneProduct
GSTA2GeneProduct
GSTA3GeneProduct
GSTA4_BOVINGeneProductENSBTAG00000004288 (Ensembl Cow)
GSTA5GeneProduct
GSTCD_BOVINGeneProductENSBTAG00000013927 (Ensembl Cow)
GSTM1GeneProduct
GSTM2GeneProduct
GSTM4GeneProduct
GSTM5GeneProduct
GSTO1GeneProduct
GSTP1_BOVINGeneProductENSBTAG00000003548 (Ensembl Cow)
GSTT1GeneProduct
GSTT2GeneProduct
GSTT2BGeneProduct
GlucuronosyltransferaseGeneProduct
Glutathione transferaseGeneProduct
HNMT_BOVINGeneProductENSBTAG00000014432 (Ensembl Cow)
HS3ST3A1GeneProduct
HS3ST3B1GeneProduct
HS3ST4GeneProduct
HS6ST2GeneProduct
IPI00686912.3GeneProductENSBTAG00000012998 (Ensembl Cow)
IPI00687876.3GeneProductENSBTAG00000001144 (Ensembl Cow)
IPI00688083.3GeneProductENSBTAG00000009093 (Ensembl Cow)
IPI00688142.3GeneProductENSBTAG00000006157 (Ensembl Cow)
IPI00689284.1GeneProductENSBTAG00000002803 (Ensembl Cow)
IPI00692810.3GeneProductENSBTAG00000001658 (Ensembl Cow)
IPI00693008.2GeneProductENSBTAG00000040000 (Ensembl Cow)
IPI00693768.3GeneProductENSBTAG00000038369 (Ensembl Cow)
IPI00694081.4GeneProductENSBTAG00000010644 (Ensembl Cow)
IPI00695153.3GeneProductENSBTAG00000001448 (Ensembl Cow)
IPI00695412.4GeneProductENSBTAG00000015647 (Ensembl Cow)
IPI00697335.1GeneProductENSBTAG00000011014 (Ensembl Cow)
IPI00698655.1GeneProductENSBTAG00000005287 (Ensembl Cow)
IPI00698855.3GeneProductENSBTAG00000025760 (Ensembl Cow)
IPI00699039.4GeneProductENSBTAG00000017595 (Ensembl Cow)
IPI00700522.1GeneProductENSBTAG00000012212 (Ensembl Cow)
IPI00701497.5GeneProductENSBTAG00000017701 (Ensembl Cow)
IPI00702562.3GeneProductENSBTAG00000008707 (Ensembl Cow)
IPI00704129.5GeneProductENSBTAG00000039319 (Ensembl Cow)
IPI00705153.2GeneProductENSBTAG00000016685 (Ensembl Cow)
IPI00705496.1GeneProductENSBTAG00000021408 (Ensembl Cow)
IPI00708458.2GeneProductENSBTAG00000017391 (Ensembl Cow)
IPI00709378.3GeneProductENSBTAG00000001692 (Ensembl Cow)
IPI00709424.4GeneProductENSBTAG00000001299 (Ensembl Cow)
IPI00710606.2GeneProductENSBTAG00000003131 (Ensembl Cow)
IPI00713683.4GeneProductENSBTAG00000002765 (Ensembl Cow)
IPI00716297.1GeneProductENSBTAG00000019249 (Ensembl Cow)
IPI00716958.3GeneProductENSBTAG00000040290 (Ensembl Cow)
IPI00726067.3GeneProductENSBTAG00000039065 (Ensembl Cow)
IPI00903985.1GeneProductENSBTAG00000007654 (Ensembl Cow)
IPI00904186.1GeneProductENSBTAG00000039973 (Ensembl Cow)
IPI00905203.2GeneProductENSBTAG00000038275 (Ensembl Cow)
IPI00906116.1GeneProductENSBTAG00000038084 (Ensembl Cow)
IPI00906608.1GeneProductENSBTAG00000011584 (Ensembl Cow)
KCAB1_BOVINGeneProductENSBTAG00000018465 (Ensembl Cow)
KCAB2_BOVINGeneProductENSBTAG00000008125 (Ensembl Cow)
LOC515352GeneProductENSBTAG00000030847 (Ensembl Cow)
LOC614317GeneProductENSBTAG00000031364 (Ensembl Cow)
MGST1_BOVINGeneProductENSBTAG00000008541 (Ensembl Cow)
MGST2_BOVINGeneProductENSBTAG00000021779 (Ensembl Cow)
MGST3_BOVINGeneProductENSBTAG00000010265 (Ensembl Cow)
MethyltransferaseGeneProduct
N-acetyltransferaseGeneProduct
NAT13_BOVINGeneProductENSBTAG00000007784 (Ensembl Cow)
NAT14_BOVINGeneProductENSBTAG00000019051 (Ensembl Cow)
NAT8GeneProduct
NDST2_BOVINGeneProductENSBTAG00000012664 (Ensembl Cow)
NM_001075173.1GeneProductENSBTAG00000003871 (Ensembl Cow)
NNMTGeneProduct
NP_001020506.1GeneProductENSBTAG00000021987 (Ensembl Cow)
NP_001029545.1GeneProductENSBTAG00000021263 (Ensembl Cow)
NP_001029801.1GeneProductENSBTAG00000000140 (Ensembl Cow)
NP_001040025.1GeneProductENSBTAG00000001842 (Ensembl Cow)
NP_001068630.1GeneProductENSBTAG00000002974 (Ensembl Cow)
NP_001069002.1GeneProductENSBTAG00000015241 (Ensembl Cow)
NP_001069154.1GeneProductENSBTAG00000002706 (Ensembl Cow)
NP_001069590.1GeneProductENSBTAG00000007449 (Ensembl Cow)
NP_001069607.1GeneProductENSBTAG00000034106 (Ensembl Cow)
NP_001069613.1GeneProductENSBTAG00000016968 (Ensembl Cow)
NP_001069670.1GeneProductENSBTAG00000011976 (Ensembl Cow)
NP_001069683.1GeneProductENSBTAG00000000188 (Ensembl Cow)
NP_001069735.1GeneProductENSBTAG00000010419 (Ensembl Cow)
NP_001069986.1GeneProductENSBTAG00000006273 (Ensembl Cow)
NP_001071381.1GeneProductENSBTAG00000020898 (Ensembl Cow)
NP_001071429.1GeneProductENSBTAG00000007316 (Ensembl Cow)
NP_001073084.1GeneProductENSBTAG00000009839 (Ensembl Cow)
NP_001075096.1GeneProductENSBTAG00000014940 (Ensembl Cow)
NP_001076882.1GeneProductENSBTAG00000013489 (Ensembl Cow)
NP_001077117.1GeneProductENSBTAG00000003721 (Ensembl Cow)
NP_001091480.1GeneProductENSBTAG00000004328 (Ensembl Cow)
NP_001091500.1GeneProductENSBTAG00000016747 (Ensembl Cow)
NP_001092408.1GeneProductENSBTAG00000003632 (Ensembl Cow)
NP_001092414.1GeneProductENSBTAG00000004040 (Ensembl Cow)
NP_001092474.1GeneProductENSBTAG00000003073 (Ensembl Cow)
NP_001093836.1GeneProductENSBTAG00000018240 (Ensembl Cow)
NP_001094774.1GeneProductENSBTAG00000010841 (Ensembl Cow)
NP_001095549.1GeneProductENSBTAG00000008778 (Ensembl Cow)
NP_001095558.1GeneProductENSBTAG00000001582 (Ensembl Cow)
NP_001096716.1GeneProductENSBTAG00000011387 (Ensembl Cow)
NP_777187.1GeneProductENSBTAG00000026181 (Ensembl Cow)
Q95KN3_BOVINGeneProductENSBTAG00000001021 (Ensembl Cow)
ST1A1_BOVINGeneProductENSBTAG00000008635 (Ensembl Cow)
ST1B1_BOVINGeneProductENSBTAG00000001249 (Ensembl Cow)
ST1E1_BOVINGeneProductENSBTAG00000011952 (Ensembl Cow)
SULT1C2GeneProduct
SULT1C4GeneProduct
SULT2A1GeneProduct
SULT2B1GeneProduct
Substrate-AaMetabolite
Substrate-AcMetabolite
Substrate-CH3Metabolite
Substrate-GlMetabolite
Substrate-NH2Metabolite
Substrate-O-RMetabolite
Substrate-OHMetabolite
Substrate-SGMetabolite
Substrate-SHMetabolite
Substrate-SO3HMetabolite
Substrate=OMetabolite
SulfotransferaseGeneProduct
TPMT_BOVINGeneProductENSBTAG00000019300 (Ensembl Cow)
UGT1A10GeneProduct
UGT1A1GeneProduct751790 (Entrez Gene)
UGT1A3GeneProduct
UGT1A4GeneProduct
UGT1A5GeneProduct
UGT1A6GeneProduct286792 (Entrez Gene)
UGT1A7GeneProduct
UGT1A9GeneProduct
UGT2A1GeneProduct
UGT2A2GeneProduct
UGT2B11GeneProduct
UGT2B15GeneProduct
UGT2B17GeneProduct
UGT2B28GeneProduct
UGT2B4GeneProduct
UGT2B7GeneProduct
XR_027890.2GeneProductENSBTAG00000007115 (Ensembl Cow)
Xenobiotic substrateMetabolite

Annotated Interactions

No annotated interactions
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