Insulin signaling (Gallus gallus)

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1PI 3-KinaseVesicular TraffickingInsulin Receptor SubstratesMetabolic Regulationp70 S6 Kinasesp90 Rsk KinasesRas-MAPK SignalingMEK/MAP KinasesTranscriptional Regulators & Immediate Early GenesModulators of Insulin ActionTranslation RegulationGlucose TransportPDK/Akt SignalingTor SignalingENPP1ELK1PIK3C2APPP1R3ASOCS3IGF1RMAP4K1MAPK7PRKCQIRS4GRB2PTPN1EIF4EEIF4EBP1RPS6KA5AKT2LIPEMAP3K9KIF3ASHC2RHOQRPS6KA1MAP3K3MAP3K14STX4AVAMP2CBLBSHC3GSK3ACBLCRKMAPK3EGR1PRKAA2SORBS1MYO1CARF1MAPK9MAPK8MAP2K6PIK3R3MAPK14RPS6KB2PIK3R1PTPRFMAP4K5MAP3K6SGK3XBP1SLC2A1RAC1PIK3CAAKT1SNAP23SGK2IKBKBGRB14FLOT1RAF1MAPK10SOS2PDPK1STXBP3RHEBMAP2K1STXBP2MAPK4STXBP1PTPN11PFKMCBLCPTENSH2B2GRB10MAP3K10KIF5BINPPL1PRKCDMAP3K12HRASRCJMB04_5i17MINK1MAPK1JUNRAC2MAP3K7INSRPIK3CGSOCS1RAPGEF1GYS2MAP3K8RPS6KA2GYG1MAP2K4MAP2K2FOSSGK1TSC1RAB4ASNAP25PIK3C2GPRKCBRCJMB04_4j14PFKLSRFFRAP1PIK3R4TBC1D4RCJMB04_36h7PSCD3MAPK11MAP3K2EHD1RPS6KA3MAP3K1PIK3CBMAPK13MAP3K11SHC1RPS6KA6TPTEMAP4K2FOXO1AGSK3BRCJMB04_8f10GAB1RCJMB04_16p24RHOJFOXO3ARF6IRS2CAP1PIK3C3TRIB3INPP4AMAPK8PIK3R2GYS1MAPK12RRADSLC2A4MAP4K3RCJMB04_5a10MAP3K5PRKCZSOS1TSC2MAP4K4RCJMB04_34i9MAP3K4PRKCHMAP2K7SNX26STXBP4IRS1EHD2MAP3K13PRKAA1RPS6KA4PIK3CD


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP481(r28132) with a 72% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Quon MJ, Campfield LA; ''A mathematical model and computer simulation study of insulin sensitive glucose transporter regulation.''; J Theor Biol, 1991 PubMed Europe PMC Scholia
  2. Bevan P; ''Insulin signalling.''; J Cell Sci, 2001 PubMed Europe PMC Scholia
  3. Saltiel AR, Kahn CR; ''Insulin signalling and the regulation of glucose and lipid metabolism.''; Nature, 2001 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
116788view09:57, 14 May 2021EweitzModified title
95775view14:28, 19 January 2018MkutmonHomology conversion update
74226view15:18, 8 April 2014EgonwRemoved a data source where no ID was given.
68843view17:19, 8 July 2013MaintBotUpdated to 2013 gpml schema
67396view10:55, 26 June 2013DdiglesOntology Term : 'insulin signaling pathway' added !
47787view16:22, 6 April 2012Khanspersupdated xref
40981view22:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
33905view18:01, 9 December 2009MaintBotAutomatic update of empty xrefs
33433view14:55, 30 November 2009MaintBotRemoved group label
31487view21:28, 13 August 2009MaintBotFixed text labels
30312view20:40, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct395928 (Entrez Gene)
AKT2GeneProduct
ARF1GeneProduct420398 (Entrez Gene)
ARF6GeneProduct
CAP1GeneProduct
CBLGeneProduct374038 (Entrez Gene)
CBLBGeneProduct418406 (Entrez Gene)
CBLCGeneProduct
CRKGeneProduct417553 (Entrez Gene)
EGR1GeneProduct373931 (Entrez Gene)
EHD1GeneProduct
EHD2GeneProduct
EIF4EGeneProduct422703 (Entrez Gene)
EIF4EBP1GeneProduct426773 (Entrez Gene)
ELK1GeneProduct
ENPP1GeneProduct426929 (Entrez Gene)
FLOT1GeneProduct
FOSGeneProduct
FOXO1AGeneProduct374231 (Entrez Gene)
FOXO3GeneProduct421769 (Entrez Gene)
FRAP1GeneProduct419455 (Entrez Gene)
GAB1GeneProduct422456 (Entrez Gene)
GRB10GeneProduct420948 (Entrez Gene)
GRB14GeneProduct424183 (Entrez Gene)
GRB2GeneProduct386572 (Entrez Gene)
GSK3AGeneProduct
GSK3BGeneProduct418335 (Entrez Gene)
GYG1GeneProduct425050 (Entrez Gene)
GYS1GeneProduct
GYS2GeneProduct418201 (Entrez Gene)
HRASGeneProduct396229 (Entrez Gene)
IGF1RGeneProduct395889 (Entrez Gene)
IKBKBGeneProduct426792 (Entrez Gene)
INPP4AGeneProduct418690 (Entrez Gene)
INPPL1GeneProduct
INSRGeneProduct420133 (Entrez Gene)
IRS1GeneProduct429126 (Entrez Gene)
IRS2GeneProduct428017 (Entrez Gene)
IRS4GeneProduct
JUNGeneProduct424673 (Entrez Gene)
KIF3AGeneProduct416332 (Entrez Gene)
KIF5BGeneProduct420472 (Entrez Gene)
LIPEGeneProduct
MAP2K1GeneProduct415549 (Entrez Gene)
MAP2K2GeneProduct396349 (Entrez Gene)
MAP2K4GeneProduct417312 (Entrez Gene)
MAP2K6GeneProduct
MAP2K7GeneProduct
MAP3K10GeneProduct
MAP3K11GeneProduct
MAP3K12GeneProduct
MAP3K13GeneProduct424876 (Entrez Gene)
MAP3K1GeneProduct427144 (Entrez Gene)
MAP3K14GeneProduct419964 (Entrez Gene)
MAP3K2GeneProduct424225 (Entrez Gene)
MAP3K3GeneProduct419954 (Entrez Gene)
MAP3K4GeneProduct421579 (Entrez Gene)
MAP3K5GeneProduct421688 (Entrez Gene)
MAP3K6GeneProduct
MAP3K7GeneProduct421808 (Entrez Gene)
MAP3K8GeneProduct420479 (Entrez Gene)
MAP3K9GeneProduct776822 (Entrez Gene)
MAP4K1GeneProduct
MAP4K2GeneProduct
MAP4K3GeneProduct
MAP4K4GeneProduct418714 (Entrez Gene)
MAP4K5GeneProduct423576 (Entrez Gene)
MAPK10GeneProduct422592 (Entrez Gene)
MAPK11GeneProduct417739 (Entrez Gene)
MAPK12GeneProduct769763 (Entrez Gene)
MAPK1GeneProduct373953 (Entrez Gene)
MAPK13GeneProduct771145 (Entrez Gene)
MAPK14GeneProduct421183 (Entrez Gene)
MAPK3GeneProduct
MAPK4GeneProduct
MAPK7GeneProduct
MAPK8GeneProduct423778 (Entrez Gene)
MAPK9GeneProduct395983 (Entrez Gene)
MINK1GeneProduct
MYO1CGeneProduct417555 (Entrez Gene)
PDPK1GeneProduct416588 (Entrez Gene)
PFKLGeneProduct769850 (Entrez Gene)
PFKMGeneProduct374064 (Entrez Gene)
PIK3C2AGeneProduct423070 (Entrez Gene)
PIK3C2GGeneProduct418181 (Entrez Gene)
PIK3C3GeneProduct
PIK3CAGeneProduct424971 (Entrez Gene)
PIK3CBGeneProduct424826 (Entrez Gene)
PIK3CDGeneProduct419444 (Entrez Gene)
PIK3CGGeneProduct417706 (Entrez Gene)
PIK3R1GeneProduct427171 (Entrez Gene)
PIK3R2GeneProduct771142 (Entrez Gene)
PIK3R3GeneProduct
PIK3R4GeneProduct428449 (Entrez Gene)
PPP1R3AGeneProduct427858 (Entrez Gene)
PRKAA1GeneProduct427185 (Entrez Gene)
PRKAA2GeneProduct429110 (Entrez Gene)
PRKCBGeneProduct416567 (Entrez Gene)
PRKCDGeneProduct415905 (Entrez Gene)
PRKCHGeneProduct423518 (Entrez Gene)
PRKCQGeneProduct
PRKCZGeneProduct419399 (Entrez Gene)
PSCD3GeneProduct416626 (Entrez Gene)
PTENGeneProduct423675 (Entrez Gene)
PTPN11GeneProduct395815 (Entrez Gene)
PTPN1GeneProduct395688 (Entrez Gene)
PTPRFGeneProduct424568 (Entrez Gene)
RAB4AGeneProduct421532 (Entrez Gene)
RAC1GeneProduct395871 (Entrez Gene)
RAC2GeneProduct418044 (Entrez Gene)
RAF1GeneProduct396245 (Entrez Gene)
RAPGEF1GeneProduct417173 (Entrez Gene)
RCJMB04_16p24GeneProduct424991 (Entrez Gene)
RCJMB04_34i9GeneProduct417579 (Entrez Gene)
RCJMB04_36h7GeneProduct415557 (Entrez Gene)
RCJMB04_4j14GeneProduct417637 (Entrez Gene)
RCJMB04_5a10GeneProduct417430 (Entrez Gene)
RCJMB04_5i17GeneProduct415419 (Entrez Gene)
RCJMB04_8f10GeneProduct416496 (Entrez Gene)
RHEBGeneProduct420434 (Entrez Gene)
RHOJGeneProduct423513 (Entrez Gene)
RHOQGeneProduct395114 (Entrez Gene)
RPS6KA1GeneProduct
RPS6KA2GeneProduct421570 (Entrez Gene)
RPS6KA3GeneProduct418605 (Entrez Gene)
RPS6KA4GeneProduct
RPS6KA5GeneProduct423408 (Entrez Gene)
RPS6KA6GeneProduct422273 (Entrez Gene)
RPS6KB2GeneProduct
RRADGeneProduct415790 (Entrez Gene)
SGK1GeneProduct395133 (Entrez Gene)
SGK2GeneProduct419166 (Entrez Gene)
SGK3GeneProduct420167 (Entrez Gene)
SH2B2GeneProduct771172 (Entrez Gene)
SHC1GeneProduct
SHC2GeneProduct770341 (Entrez Gene)
SHC3GeneProduct431265 (Entrez Gene)
SLC2A1GeneProduct396130 (Entrez Gene)
SLC2A4GeneProduct
SNAP23GeneProduct423235 (Entrez Gene)
SNAP25GeneProduct396444 (Entrez Gene)
SNX26GeneProduct
SOCS1GeneProduct416630 (Entrez Gene)
SOCS3GeneProduct395299 (Entrez Gene)
SORBS1GeneProduct423749 (Entrez Gene)
SOS1GeneProduct
SOS2GeneProduct423572 (Entrez Gene)
SRFGeneProduct
STX4AGeneProduct
STXBP1GeneProduct404293 (Entrez Gene)
STXBP2GeneProduct
STXBP3GeneProduct424341 (Entrez Gene)
STXBP4GeneProduct417393 (Entrez Gene)
TBC1D4GeneProduct
TPTEGeneProduct418885 (Entrez Gene)
TRIB3GeneProduct
TSC1GeneProduct417166 (Entrez Gene)
TSC2GeneProduct
VAMP2GeneProduct424827 (Entrez Gene)
XBP1GeneProduct

Annotated Interactions

No annotated interactions
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