Regulation of actin cytoskeleton (Gallus gallus)
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Actin polymerization
PI3K
GPCR
+p
Gene Expression
RTK
Focal complex
assembly
?
Stabilization
of actin
RAS
PI3K
Adherens junction
pathway
GF
Growth Factor (GF)
MAPK Signaling
pathway
RTK
Chemotactic factor
GPCR
-p
Focal adhesion
assembly
Lamellipodia
Actomyosin
assembly contraction
Focal adhesion
pathway
Actin
polymerization
stress fiber
Filipodia
RAS
Actin polymerization
stress fiber
Chemotatic factor
Focal adhesion
pathway
FGFR4
PIP5K1C
MAP2K2
WAS
CHRM5
CSK
NRAS
FGFR1
PFN1
LOC442775
TPTE
RCJMB04_22k13
TPTE
FGF4
TPTE
FGF9
MRAS
FGF20
PIP2
ARHGEF1
PDGFB
MSN
GNA13
TMSB4X
MYL3
PIK3CG
PAK4
EGF
RAC1P4
RDX
IQGAP1
MYL1
MAPK1
CHRM3
FGF14
PIK3C2A
PIP5K1A
RHOA
FGF23
TPTE
RCJMB04_4h19
FGF1
FGF11
LIMK1
C11orf13
SSH3
ARHGEF6
PIP4K2A
RAC3
PIK3CB
FGF16
VCL
PIK3R5
CDC42
ARPC5
ARPC5
MAP2K1
CRK
Bradykinin
PIK3R3
APC
FGF12
Apc2
TPTE
SLC9A1
PXN
ABI2
PIK3C2G
PIK3R1
MYH10
ARHGEF7
MAPK4
FGF2
CHRM2
RRAS
TPTE
PIP4K2A
PIP3
DOCK1
RCJMB04_5i17
BAIAP2
ROCK1
PAK7
FGF17
SSH1
NCKAP1
PIK3CD
FGF18
FGFR2
F2R
FGF8
PTK2
FGF7
LOC426359
PAK1
CYFIP2
FN1
EZR
BDKRB1
MYLK
GRLF1
FGF6
ITGA1
PIP2
GNG12
PDGFRA
GSN
FGF22
PIK3R2
SOS2
RCJMB04_1h13
KRAS
Pik3c2b
RCJMB04_23c5
FGF21
CHRM1
PDGFRB
MAPK3
FGF5
BRAF
PDGFA
SOS1
SSH2
PFN1
Acetylcholine
PIK3C3
FGD1
EGFR
RCJMB04_4h19
CHRM4
GNA12
BAIAP2
PAK2
F2
VIL1
RCJMB04_4h19
RAC2
RAF1
PAK3
RAC1
RCJMB04_20j15
ARHGEF4
PIP5K2C
GIT1
BDKRB2
LPS
MOS
WASF1
FGF13
CFL1
BCAR1
CFL2
FGF10
PIP5KL1
RRAS2
ARHGEF6
FGF3
FGFR3
PAK6
VCL
CD14
RCJMB04_1h13
PIK3R4
PIK3CA
VAV1
RCJMB04_1h13
ROCK2
PIP4K2B
ENAH
Description
No description
Comments
GenMAPP notes
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
GenMAPP remarks
Adapted from KEGG (right-click to see notes)
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP51(r20783)
with a 76% conversion rate.
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Bibliography
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Revision
Action
Time
User
Comment
117210
view
09:26, 19 May 2021
Eweitz
Modified title
109469
view
10:59, 18 March 2020
L Dupuis
Converted interaction lines to graphical lines where applicable
72069
view
17:52, 24 October 2013
MaintBot
Updated data sources
68796
view
17:14, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67625
view
11:35, 26 June 2013
Ddigles
Ontology Term : 'cell adhesion signaling pathway' added !
47796
view
16:38, 6 April 2012
Khanspers
updated xrefs
40928
view
22:51, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33859
view
17:45, 9 December 2009
MaintBot
Automatic update of empty xrefs
33495
view
15:12, 30 November 2009
MaintBot
Removed group label
31542
view
21:49, 13 August 2009
MaintBot
Fixed text labels
30393
view
21:07, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ABI2
GeneProduct
424108 (Entrez Gene)
APC
GeneProduct
415607 (Entrez Gene)
ARHGEF1
GeneProduct
ARHGEF4
GeneProduct
424761 (Entrez Gene)
ARHGEF6
GeneProduct
422247 (Entrez Gene)
ARHGEF7
GeneProduct
418761 (Entrez Gene)
ARPC5
GeneProduct
429075 (Entrez Gene)
Acetylcholine
GeneProduct
Apc2
GeneProduct
BAIAP2
GeneProduct
422077 (Entrez Gene)
BCAR1
GeneProduct
415691 (Entrez Gene)
BDKRB1
GeneProduct
772372 (Entrez Gene)
BDKRB2
GeneProduct
428906 (Entrez Gene)
BRAF
GeneProduct
396239 (Entrez Gene)
Bradykinin
GeneProduct
C11orf13
GeneProduct
CD14
GeneProduct
CDC42
GeneProduct
395917 (Entrez Gene)
CFL1
GeneProduct
CFL2
GeneProduct
423320 (Entrez Gene)
CHRM1
GeneProduct
CHRM2
GeneProduct
418126 (Entrez Gene)
CHRM3
GeneProduct
396364 (Entrez Gene)
CHRM4
GeneProduct
423195 (Entrez Gene)
CHRM5
GeneProduct
428881 (Entrez Gene)
CRK
GeneProduct
417553 (Entrez Gene)
CSK
GeneProduct
396396 (Entrez Gene)
CYFIP2
GeneProduct
416246 (Entrez Gene)
DOCK1
GeneProduct
423960 (Entrez Gene)
EGF
GeneProduct
408035 (Entrez Gene)
EGFR
GeneProduct
ENAH
GeneProduct
EZR
GeneProduct
395701 (Entrez Gene)
F2
GeneProduct
395306 (Entrez Gene)
F2R
GeneProduct
427212 (Entrez Gene)
FGD1
GeneProduct
FGF10
GeneProduct
FGF11
GeneProduct
FGF12
GeneProduct
395704 (Entrez Gene)
FGF13
GeneProduct
414831 (Entrez Gene)
FGF1
GeneProduct
396094 (Entrez Gene)
FGF14
GeneProduct
395554 (Entrez Gene)
FGF16
GeneProduct
422330 (Entrez Gene)
FGF17
GeneProduct
FGF18
GeneProduct
395453 (Entrez Gene)
FGF20
GeneProduct
428779 (Entrez Gene)
FGF21
GeneProduct
FGF22
GeneProduct
FGF23
GeneProduct
428104 (Entrez Gene)
FGF2
GeneProduct
396413 (Entrez Gene)
FGF3
GeneProduct
396267 (Entrez Gene)
FGF4
GeneProduct
428857 (Entrez Gene)
FGF5
GeneProduct
770457 (Entrez Gene)
FGF6
GeneProduct
768907 (Entrez Gene)
FGF7
GeneProduct
415439 (Entrez Gene)
FGF8
GeneProduct
396313 (Entrez Gene)
FGF9
GeneProduct
378917 (Entrez Gene)
FGFR1
GeneProduct
396516 (Entrez Gene)
FGFR2
GeneProduct
396259 (Entrez Gene)
FGFR3
GeneProduct
396515 (Entrez Gene)
FGFR4
GeneProduct
FN1
GeneProduct
396133 (Entrez Gene)
GIT1
GeneProduct
GNA12
GeneProduct
769924 (Entrez Gene)
GNA13
GeneProduct
417434 (Entrez Gene)
GNG12
GeneProduct
772239 (Entrez Gene)
GRLF1
GeneProduct
GSN
GeneProduct
395774 (Entrez Gene)
IQGAP1
GeneProduct
415591 (Entrez Gene)
ITGA1
GeneProduct
395951 (Entrez Gene)
KRAS
GeneProduct
418207 (Entrez Gene)
LIMK1
GeneProduct
373922 (Entrez Gene)
LOC426359
GeneProduct
426359 (Entrez Gene)
LOC442775
GeneProduct
LPS
Metabolite
C00338 (Kegg Compound)
MAP2K1
GeneProduct
415549 (Entrez Gene)
MAP2K2
GeneProduct
396349 (Entrez Gene)
MAPK1
GeneProduct
373953 (Entrez Gene)
MAPK3
GeneProduct
MAPK4
GeneProduct
MOS
GeneProduct
428537 (Entrez Gene)
MRAS
GeneProduct
395149 (Entrez Gene)
MSN
GeneProduct
MYH10
GeneProduct
396465 (Entrez Gene)
MYL1
GeneProduct
396470 (Entrez Gene)
MYL3
GeneProduct
396067 (Entrez Gene)
MYLK
GeneProduct
396445 (Entrez Gene)
NCKAP1
GeneProduct
424000 (Entrez Gene)
NRAS
GeneProduct
419885 (Entrez Gene)
PAK1
GeneProduct
419083 (Entrez Gene)
PAK2
GeneProduct
424860 (Entrez Gene)
PAK3
GeneProduct
422342 (Entrez Gene)
PAK4
GeneProduct
770462 (Entrez Gene)
PAK6
GeneProduct
428837 (Entrez Gene)
PAK7
GeneProduct
416734 (Entrez Gene)
PDGFA
GeneProduct
374196 (Entrez Gene)
PDGFB
GeneProduct
374128 (Entrez Gene)
PDGFRA
GeneProduct
395509 (Entrez Gene)
PDGFRB
GeneProduct
770488 (Entrez Gene)
PFN1
GeneProduct
PIK3C2A
GeneProduct
423070 (Entrez Gene)
PIK3C2G
GeneProduct
418181 (Entrez Gene)
PIK3C3
GeneProduct
PIK3CA
GeneProduct
424971 (Entrez Gene)
PIK3CB
GeneProduct
424826 (Entrez Gene)
PIK3CD
GeneProduct
419444 (Entrez Gene)
PIK3CG
GeneProduct
417706 (Entrez Gene)
PIK3R1
GeneProduct
427171 (Entrez Gene)
PIK3R2
GeneProduct
771142 (Entrez Gene)
PIK3R3
GeneProduct
PIK3R4
GeneProduct
428449 (Entrez Gene)
PIK3R5
GeneProduct
417319 (Entrez Gene)
PIP2
Metabolite
C04637 (Kegg Compound)
PIP3
Metabolite
C05981 (Kegg Compound)
PIP4K2A
GeneProduct
420504 (Entrez Gene)
PIP4K2B
GeneProduct
419999 (Entrez Gene)
PIP5K1A
GeneProduct
PIP5K1C
GeneProduct
420072 (Entrez Gene)
PIP5K2C
GeneProduct
PIP5KL1
GeneProduct
PTK2
GeneProduct
396416 (Entrez Gene)
PXN
GeneProduct
395832 (Entrez Gene)
Pik3c2b
GeneProduct
RAC1
GeneProduct
395871 (Entrez Gene)
RAC1P4
GeneProduct
RAC2
GeneProduct
418044 (Entrez Gene)
RAC3
GeneProduct
395870 (Entrez Gene)
RAF1
GeneProduct
396245 (Entrez Gene)
RCJMB04_1h13
GeneProduct
415296 (Entrez Gene)
RCJMB04_20j15
GeneProduct
427243 (Entrez Gene)
RCJMB04_22k13
GeneProduct
396020 (Entrez Gene)
RCJMB04_23c5
GeneProduct
373918 (Entrez Gene)
RCJMB04_4h19
GeneProduct
396526 (Entrez Gene)
RCJMB04_5i17
GeneProduct
415419 (Entrez Gene)
RDX
GeneProduct
395511 (Entrez Gene)
RHOA
GeneProduct
395442 (Entrez Gene)
ROCK1
GeneProduct
373970 (Entrez Gene)
ROCK2
GeneProduct
374182 (Entrez Gene)
RRAS
GeneProduct
RRAS2
GeneProduct
423062 (Entrez Gene)
SLC9A1
GeneProduct
419580 (Entrez Gene)
SOS1
GeneProduct
SOS2
GeneProduct
423572 (Entrez Gene)
SSH1
GeneProduct
427699 (Entrez Gene)
SSH2
GeneProduct
417586 (Entrez Gene)
SSH3
GeneProduct
TMSB4X
GeneProduct
TPTE
GeneProduct
418885 (Entrez Gene)
VAV1
GeneProduct
VCL
GeneProduct
396422 (Entrez Gene)
VIL1
GeneProduct
396423 (Entrez Gene)
WAS
GeneProduct
WASF1
GeneProduct
421761 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Bibliography
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History
External references
DataNodes
Annotated Interactions
No annotated interactions