Eukaryotic transcription initiation (Gallus gallus)

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(small stable RNAs)Steps 2) Association of TIFs and RNA polymerase5TFIIHSteps 5) RNA elongation with CDT phosphorylationRNA polymerase IITFIIBTFIIESteps 3) DNA melting by association with TFIIHTranscription Initiation Factors (TIFs)TFIIF(recognize surface DNA geometry)TFIIHGene Regulatory ProteinsRNA pol II35TATA Box bindingproteinSteps 4) Transcription elongation by NTPs(large ribosomal RNAs)RNA polymerase ISteps 1) TBP binds TATA boxTATA3dsDNATFIIETFIID5TFIIDTFIIARNA polymerase IIITFIIA33TATATFIIB53TATA555533cell growthPrimary RNA transcript553(mRNA, snRNPs)TFIIFTFIIF3POLR2KTPTEPOLR2JGTF2H3TAF7GTF2E1ILKTAF6CCNHPOLR1DGTF2F2POLR1BPOLR3EGTF2H1GTF2E2GTF2BERCC3POLR3BTAF9MNAT1POLR3DRCJMB04_15p4TAF12POLR2CPOLR2ICDK7POLR3KGTF2H2TBPPOLR2EPOLR2APOLR1APOLR2GPOLR2FPOLR2BGTF2A2POLR2HERCC2POLR3HTAF13GTF2H4


Description

No description

Comments

GenMAPP notes 
Reference: http://www.web-books.com/MoBio/Free/Ch4E.htm
GenMAPP remarks 
right click for notes & references
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP405(r29565) with a 80% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Lee TI, Young RA; ''Regulation of gene expression by TBP-associated proteins.''; Genes Dev, 1998 PubMed Europe PMC Scholia
  2. Lemon B, Tjian R; ''Orchestrated response: a symphony of transcription factors for gene control.''; Genes Dev, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118407view14:14, 27 May 2021EweitzOntology Term : 'RNA polymerase III transcription initiation pathway' added !
118393view13:59, 27 May 2021EweitzOntology Term : 'PW:0001575' removed !
118392view13:59, 27 May 2021EweitzOntology Term : 'PW:0001274' removed !
118391view13:59, 27 May 2021EweitzOntology Term : 'PW:0001570' removed !
118390view13:58, 27 May 2021EweitzOntology Term : 'RNA polymerase III transcription initiation pathway' added !
118389view13:58, 27 May 2021EweitzOntology Term : 'RNA polymerase I transcription initiation pathway' added !
118388view13:58, 27 May 2021EweitzOntology Term : 'RNA polymerase II transcription initiation pathway' added !
118386view13:57, 27 May 2021EweitzOntology Term : 'PW:0000100' removed !
118385view13:57, 27 May 2021EweitzOntology Term : 'RNA polymerase I transcription initiation pathway' added !
118384view13:56, 27 May 2021EweitzOntology Term : 'RNA polymerase III transcription initiation pathway' added !
118381view13:55, 27 May 2021EweitzOntology Term : 'RNA polymerase II transcription initiation pathway' added !
117194view10:32, 18 May 2021EweitzModified title
68790view17:13, 8 July 2013MaintBotUpdated to 2013 gpml schema
67217view10:22, 26 June 2013Christine ChichesterOntology Term : 'transcription pathway' added !
58767view22:15, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
47789view16:25, 6 April 2012Khanspersupdated xref
40921view22:51, 1 March 2011MaintBotRemoved redundant pathway information and comments
35527view13:57, 12 February 2010Thomasadded literature
35515view13:51, 12 February 2010ThomasModified description
33852view17:42, 9 December 2009MaintBotAutomatic update of empty xrefs
33500view15:13, 30 November 2009MaintBotRemoved group label
31547view21:51, 13 August 2009MaintBotFixed text labels
30399view21:09, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CCNHGeneProduct427328 (Entrez Gene)
CDK7GeneProduct
ERCC2GeneProduct
ERCC3GeneProduct424226 (Entrez Gene)
GTF2A2GeneProduct770910 (Entrez Gene)
GTF2BGeneProduct424518 (Entrez Gene)
GTF2E1GeneProduct418328 (Entrez Gene)
GTF2E2GeneProduct771227 (Entrez Gene)
GTF2F2GeneProduct418843 (Entrez Gene)
GTF2H1GeneProduct423081 (Entrez Gene)
GTF2H2GeneProduct
GTF2H3GeneProduct771837 (Entrez Gene)
GTF2H4GeneProduct
ILKGeneProduct374018 (Entrez Gene)
MNAT1GeneProduct423521 (Entrez Gene)
POLR1AGeneProduct422910 (Entrez Gene)
POLR1BGeneProduct416710 (Entrez Gene)
POLR1DGeneProduct428713 (Entrez Gene)
POLR2AGeneProduct
POLR2BGeneProduct422621 (Entrez Gene)
POLR2CGeneProduct415635 (Entrez Gene)
POLR2EGeneProduct420103 (Entrez Gene)
POLR2FGeneProduct395486 (Entrez Gene)
POLR2GGeneProduct
POLR2HGeneProduct424954 (Entrez Gene)
POLR2IGeneProduct426289 (Entrez Gene)
POLR2JGeneProduct
POLR2KGeneProduct768387 (Entrez Gene)
POLR3BGeneProduct418071 (Entrez Gene)
POLR3DGeneProduct
POLR3EGeneProduct416620 (Entrez Gene)
POLR3HGeneProduct417990 (Entrez Gene)
POLR3KGeneProduct768505 (Entrez Gene)
RCJMB04_15p4GeneProduct423872 (Entrez Gene)
TAF12GeneProduct419585 (Entrez Gene)
TAF13GeneProduct418365 (Entrez Gene)
TAF6GeneProduct776310 (Entrez Gene)
TAF7GeneProduct422192 (Entrez Gene)
TAF9GeneProduct422152 (Entrez Gene)
TBPGeneProduct395995 (Entrez Gene)
TPTEGeneProduct418885 (Entrez Gene)

Annotated Interactions

No annotated interactions
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