Cell cycle (Gallus gallus)

From WikiPathways

Revision as of 15:18, 30 November 2009 by MaintBot (Talk | contribs)
Jump to: navigation, search
1ORC (OriginRecognition complex)DNA biosynthesis-p+p+u+u+p+pHistone DeacetylaseseSeparin+p+uCondensin+pe+pR-pointe+pS+p+pp16,15,18,19MMCM (Mini-ChromosomeMaintenance) complexSecurin+p+uG2esignaling+pTranscription Factor E2FS-phase proteins+pmediatedp27,57Growth FactorDNAGrowth Factor withdrawalDNA damage checkpointproteolysis+p+pHDAC+pMAPK(Start)G1+p+u-pp21DNA+ppathwayUbiquitineApoptosisABL1MDM2ORC3LCHEK1RBL1ORC4LCCND3SMAD4CCNE2CDC20MENEP300SCFRB114-3-3TBC1D8HDAC3SKP2E2F2GeneProductPTTG1E2F1PLK1HDAC6APC/CRBL1CDK2TP53MAD2L1CDC25ABUB1BCDC2CDH1MCM4ARFPKMYT1CDC45LMCMORC1LBUB3SMAD3CCNE1PRKDCCDKN1ABUB1CCNA1HDAC7ACCND2CCNHE2F3PTTG3E2FMPEG1CCNA1MCM2CDC6HDAC8ORCCCNB2ORC6LMCM6RCJMB04_30p22APC/CCCNA2CDC14ARCJMB04_5e12CCNA2SCFMAD2L2SKP2HDAC4ATMGADD45ACDC25BCDC2HDAC2CDC14CHDAC1MCM7CDK2CCNB3ORC2LESPL1CCNB1CDK6WEE1PCNAGSK3BRB1E2F6CDC25CE2F4ATRCDK4CDK2MCM3MAD1L1CDKN1BPTTG2DBF4CHEK2RB1CDKN2ATFDP1TGFB1HDAC5UBE2FORC5LCDC7SMC1L1MCM5


Description

No description

Comments

GenMAPP notes 
Adapted from: http://www.genome.ad.jp/kegg/pathway/hsa/hsa04110.html
GenMAPP remarks 
Right-click here to see notes
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP179(r30295) with a 62% conversion rate.

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

  1. Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, Appella E, Kastan MB, Siliciano JD; ''Activation of the ATM kinase by ionizing radiation and phosphorylation of p53.''; Science, 1998 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
109474view11:09, 18 March 2020L DupuisConverted interaction lines to graphical lines where applicable
86991view14:37, 15 July 2016MkutmonOntology Term : 'cell cycle pathway' added !
72064view17:30, 24 October 2013MaintBotremoved data source from nodes without identifier
68856view17:20, 8 July 2013MaintBotUpdated to 2013 gpml schema
62677view18:31, 1 May 2013MaintBotUpdated Ensembl and UniProt data source
40994view22:56, 1 March 2011MaintBotRemoved redundant pathway information and comments
35366view09:15, 12 February 2010MartijnVanIerselModified description
33916view18:05, 9 December 2009MaintBotAutomatic update of empty xrefs
33514view15:18, 30 November 2009MaintBotRemoved group label
31554view21:53, 13 August 2009MaintBotFixed text labels
30413view21:14, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
14-3-3GeneProduct
ABL1GeneProduct417181 (Entrez Gene) ABL1; v-abl Abelson murine leukemia viral oncogene homolog 1 [EC:2.7.1.112
APC/CGeneProduct
ARFGeneProduct
ATMGeneProduct395401 (Entrez Gene) ATM; ataxia telangiectasia mutated (includes complementation groups A C and D) [EC:2.7.1.37]
ATRGeneProductATR; ataxia telangiectasia and Rad3 related
BUB1GeneProduct421226 (Entrez Gene) BUB1; BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) [EC:2.7.1.-]
BUB1BGeneProduct378922 (Entrez Gene) BUB1B; BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) [EC:2.7.1.-]
BUB3GeneProduct423949 (Entrez Gene) BUB3; BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)
CCNA1GeneProduct418901 (Entrez Gene) CCNA1; cyclin A1
CCNA2GeneProduct396172 (Entrez Gene) CCNA2; cyclin A2
CCNB1GeneProductCCNB1; cyclin B1
CCNB2GeneProduct415400 (Entrez Gene) CCNB2; cyclin B2
CCNB3GeneProductCCNB3; cyclin B
CCND2GeneProduct374047 (Entrez Gene) CCND2; cyclin D2
CCND3GeneProduct419928 (Entrez Gene) CCND3; cyclin D3
CCNE1GeneProduct426117 (Entrez Gene) CCNE1; cyclin E
CCNE2GeneProduct420231 (Entrez Gene) CCNE2; cyclin E
CCNHGeneProduct427328 (Entrez Gene) CCNH; cyclin H
CDC14AGeneProductCDC14A; CDC14 cell division cycle 14 homolog A (S. cerevisiae
CDC14CGeneProduct427473 (Entrez Gene) CDC14B; CDC14 cell division cycle 14 homolog B (S. cerevisiae
CDC20GeneProduct424563 (Entrez Gene) CDC20; CDC20 cell division cycle 20 homolog (S. cerevisiae
CDC2GeneProduct396252 (Entrez Gene) CDC2; cell division cycle 2 G1 to S and G2 to M [EC:2.7.1.-
CDC25AGeneProduct420375 (Entrez Gene) CDC25A; cell division cycle 25A [EC:3.1.3.48]
CDC25BGeneProductCDC25B; cell division cycle 25B [EC:3.1.3.48]
CDC25CGeneProductCDC25C; cell division cycle 25C [EC:3.1.3.48]
CDC45LGeneProduct416776 (Entrez Gene) CDC45L; CDC45 cell division cycle 45-like (S. cerevisiae)
CDC6GeneProductCDC6; CDC6 cell division cycle 6 homolog (S. cerevisiae
CDC7GeneProduct424507 (Entrez Gene) CDC7L1; CDC7 cell division cycle 7-like 1 (S. cerevisiae) [EC:2.7.1.-]
CDH1GeneProduct415860 (Entrez Gene)
CDK2GeneProductCDK2; cyclin-dependent kinase 2 [EC:2.7.1.-]
CDK4GeneProductCDK4; cyclin-dependent kinase 4 [EC:2.7.1.-]
CDK6GeneProduct420558 (Entrez Gene) CDK6; cyclin-dependent kinase 6 [EC:2.7.1.-]
CDKN1AGeneProduct
CDKN1BGeneProductCDKN1A; cyclin-dependent kinase inhibitor 1A (p21 Cip1)
CDKN2AGeneProduct
CHEK1GeneProductCHEK1; CHK1 checkpoint homolog (S. pombe) [EC:2.7.1.-]
CHEK2GeneProduct768913 (Entrez Gene) CHEK2; CHK2 checkpoint homolog (S. pombe) [EC:2.7.1.-]
DBF4GeneProduct420536 (Entrez Gene) ASK; activator of S phase kinas
E2FGeneProduct
E2F1GeneProduct396142 (Entrez Gene) E2F1; E2F transcription factor 1
E2F2GeneProductE2F2; E2F transcription factor 2
E2F3GeneProduct420824 (Entrez Gene) E2F3; E2F transcription factor 3
E2F4GeneProduct769430 (Entrez Gene) E2F4; E2F transcription factor 4 p107/p130-binding
E2F6GeneProductE2F6; E2F transcription factor 6
EP300GeneProduct418000 (Entrez Gene) EP300; E1A binding protein p300
ESPL1GeneProduct425536 (Entrez Gene) ESPL1; extra spindle poles like 1 (S. cerevisiae
GADD45AGeneProduct
GSK3BGeneProduct418335 (Entrez Gene) GSK3B; glycogen synthase kinase 3 beta [EC:2.7.1.37]
GeneProductGeneProduct
HDAC1GeneProduct373961 (Entrez Gene) HDAC1; histone deacetylase 1
HDAC2GeneProduct395635 (Entrez Gene) HDAC2; histone deacetylase 2
HDAC3GeneProduct395506 (Entrez Gene) HDAC3; histone deacetylase 3
HDAC4GeneProduct374207 (Entrez Gene) HDAC4; histone deacetylase 4
HDAC5GeneProductHDAC5; histone deacetylase 5
HDAC6GeneProductHDAC6; histone deacetylase 6
HDAC7AGeneProduct426885 (Entrez Gene) HDAC7A; histone deacetylase 7
HDAC8GeneProduct422182 (Entrez Gene) HDAC8; histone deacetylase
MAD1L1GeneProduct427658 (Entrez Gene) MAD1L1; MAD1 mitotic arrest deficient-like 1 (yeast
MAD2L1GeneProduct422675 (Entrez Gene) MAD2L1; MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L2GeneProduct419493 (Entrez Gene) MAD2L2; MAD2 mitotic arrest deficient-like 2 (yeast)
MCMGeneProduct
MCM2GeneProduct416027 (Entrez Gene) MCM2; MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae
MCM3GeneProduct422043 (Entrez Gene) MCM3; MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)
MCM4GeneProduct426764 (Entrez Gene) MCM4; MCM4 minichromosome maintenance deficient 4 (S. cerevisiae
MCM5GeneProduct418058 (Entrez Gene) MCM5; MCM5 minichromosome maintenance deficient 5 cell division cycle 46 (S. cerevisiae)
MCM6GeneProduct424295 (Entrez Gene) MCM6; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog S. pombe) (S. cerevisiae)
MCM7GeneProductMCM7; MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)
MDM2GeneProductMDM2; Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse)
MENGeneProduct
MPEG1GeneProduct
ORCGeneProduct
ORC1LGeneProduct424640 (Entrez Gene) ORC1L; origin recognition complex subunit 1-like (yeast)
ORC2LGeneProduct424077 (Entrez Gene) ORC2L; origin recognition complex subunit 2-like (yeast)
ORC3LGeneProduct421822 (Entrez Gene) ORC3L; origin recognition complex subunit 3-like (yeast)
ORC4LGeneProduct424307 (Entrez Gene) ORC4L; origin recognition complex subunit 4-like (yeast)
ORC5LGeneProduct417714 (Entrez Gene) ORC5L; origin recognition complex subunit 5-like (yeast)
ORC6LGeneProduct415749 (Entrez Gene) ORC6L; origin recognition complex subunit 6-like (yeast)
PCNAGeneProduct373984 (Entrez Gene) PCNA; proliferating cell nuclear antigen
PKMYT1GeneProductPKMYT1; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinas
PLK1GeneProduct416575 (Entrez Gene) PLK; polo-like kinase (Drosophila) [EC:2.7.1.-]
PRKDCGeneProduct395376 (Entrez Gene) PRKDC; protein kinase DNA-activated catalytic polypeptide [EC:2.7.1.37]
PTTG1GeneProduct416158 (Entrez Gene) PTTG1; pituitary tumor-transforming
PTTG2GeneProductPTTG2; pituitary tumor-transforming
PTTG3GeneProductPTTG3; pituitary tumor-transforming
RB1GeneProduct386582 (Entrez Gene) RB1; retinoblastoma 1 (including osteosarcoma)
RBL1GeneProduct419126 (Entrez Gene) RBL1; retinoblastoma-like 1 (p107)
RCJMB04_30p22GeneProduct420206 (Entrez Gene) E2F5; E2F transcription factor 5 p130-binding
RCJMB04_5e12GeneProduct427820 (Entrez Gene) YWHAG; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma polypeptid
SCFGeneProduct
SKP2GeneProduct427437 (Entrez Gene) SKP2; S-phase kinase-associated protein 2 (p45
SMAD3GeneProduct395132 (Entrez Gene) MADH3; MAD mothers against decapentaplegic homolog 3 (Drosophila)
SMAD4GeneProductMADH4; MAD mothers against decapentaplegic homolog 4 (Drosophila)
SMC1L1GeneProductSMC1L1; SMC1 structural maintenance of chromosomes 1-like 1 (yeast
TBC1D8GeneProduct428012 (Entrez Gene)
TFDP1GeneProduct418739 (Entrez Gene) TFDP1; transcription factor Dp-1
TGFB1GeneProduct
TP53GeneProduct
UBE2FGeneProductUBE2F; ubiquitin-conjugating enzyme E2F (UBC6 homolog C. elegans
WEE1GeneProduct423045 (Entrez Gene) WEE1; WEE1+ homolog (S. pombe) [EC:2.7.1.112]

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP844"