Insulin Signaling (Pan troglodytes)

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1Transcriptional Regulators & Immediate Early GenesPI 3-KinaseTranslation RegulationMetabolic RegulationInsulin Receptor SubstratesTor Signalingp70 S6 KinasesPDK/Akt SignalingRas-MAPK SignalingGlucose TransportVesicular TraffickingMEK/MAP Kinasesp90 Rsk KinasesModulators of Insulin ActionSHC3IGF1RINSRMAP2K6MAP3K13FOSPIK3C2ARPS6KA4MAP3K1MAP4K2KIF5BMAP2K7FRAP1GSK3AEHD2RAC1PFKMRRADIRS1HRASMAPK12GAB1PRKAA1PTENSTXBP3RPS6KA2MAP3K11MAPK4MAP3K7ARF1SH2B2MAP3K12EGR1GYS1MAP3K5EHD1GYG1RPS6KB1PIK3C2GTSC1MAPK1IRS4MAP4K3FOXO3ATSC2MAPK14SNX26MAP3K2PRKAA2RAB4ASGKPIK3R3MAP2K3MAP2K5SLC2A4EIF4EBP1SHC1STXBP4PSCD3PRKCHEIF4EKIF3AMAPK9PIK3R2RPS6KA5PDPK1MAPK3PTPN1CAP1PIK3CDPIK3R4MAP3K6SOS2SRFRPS6KA3MAP3K4STX4APFKLSGK2VAMP2PIK3CBMAPK8INPPL1RAPGEF1ARF6SOS1PRKCDMAP2K2RHOXF2STXBP1MYO1CGRB14MAP4K4PTPRFCBLBFLOT1MAP3K9SNAP25MAP2K1MAP4K1MAPK11INPP4ARHOQPIK3R1ELK1MAP2K4PRKCAPIK3C3GSK3BXBP1JUNMINK1SLC2A1PTPN11IKBKBCRKPIK3CGIRS2TBC1D4MAP3K14GRB2MAPK13MAPK10SNAP23TRIB3PRKCB1PRKCQRAC2CBLMAP4K5RPS6KB2AKT1SORBS1CBLCPRKCIMAP3K8GRB10MAPK7MAPK6PRKCZRAF1FOXO1GYS2SOCS3SGK3FLOT2SHC2RPS6KA6PPP1R3AMAPK8RHEBRPS6KA1PIK3CARHOJAKT2MAP3K3LIPESTXBP2ENPP1SOCS1MAP3K10


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP481(r28132) with a 72% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Bevan P; ''Insulin signalling.''; J Cell Sci, 2001 PubMed Europe PMC Scholia
  2. Quon MJ, Campfield LA; ''A mathematical model and computer simulation study of insulin sensitive glucose transporter regulation.''; J Theor Biol, 1991 PubMed Europe PMC Scholia
  3. Saltiel AR, Kahn CR; ''Insulin signalling and the regulation of glucose and lipid metabolism.''; Nature, 2001 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
69319view18:44, 8 July 2013MaintBotUpdated to 2013 gpml schema
48148view18:41, 9 May 2012MaintBotUpdating from human to fix xrefs
41629view02:03, 2 March 2011MaintBotRemoved redundant pathway information and comments
34356view22:24, 9 December 2009MaintBotAutomatic update of empty xrefs
33517view15:19, 30 November 2009MaintBotRemoved group label
31557view21:54, 13 August 2009MaintBotFixed text labels
30416view21:15, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct740898 (Entrez Gene)
AKT2GeneProduct456035 (Entrez Gene)
ARF1GeneProduct
ARF6GeneProduct452892 (Entrez Gene)
CAP1GeneProduct746432 (Entrez Gene)
CBLGeneProduct451690 (Entrez Gene)
CBLBGeneProduct460566 (Entrez Gene)
CBLCGeneProduct
CRKGeneProduct747142 (Entrez Gene)
EGR1GeneProduct462097 (Entrez Gene)
EHD1GeneProduct744047 (Entrez Gene)
EHD2GeneProduct456170 (Entrez Gene)
EIF4EGeneProduct
EIF4EBP1GeneProduct464114 (Entrez Gene)
ELK1GeneProduct
ENPP1GeneProduct463002 (Entrez Gene)
FLOT1GeneProduct471961 (Entrez Gene)
FLOT2GeneProduct454537 (Entrez Gene)
FOSGeneProduct453047 (Entrez Gene)
FOXO1GeneProduct467352 (Entrez Gene)
FOXO3AGeneProduct
FRAP1GeneProduct
GAB1GeneProduct461516 (Entrez Gene)
GRB10GeneProduct463410 (Entrez Gene)
GRB14GeneProduct459695 (Entrez Gene)
GRB2GeneProduct737245 (Entrez Gene)
GSK3AGeneProduct456071 (Entrez Gene)
GSK3BGeneProduct470896 (Entrez Gene)
GYG1GeneProduct460765 (Entrez Gene)
GYS1GeneProduct
GYS2GeneProduct465336 (Entrez Gene)
HRASGeneProduct466302 (Entrez Gene)
IGF1RGeneProduct453676 (Entrez Gene)
IKBKBGeneProduct472749 (Entrez Gene)
INPP4AGeneProduct470448 (Entrez Gene)
INPPL1GeneProduct451403 (Entrez Gene)
INSRGeneProduct
IRS1GeneProduct459985 (Entrez Gene)
IRS2GeneProduct452657 (Entrez Gene)
IRS4GeneProduct
JUNGeneProduct456893 (Entrez Gene)
KIF3AGeneProduct450168 (Entrez Gene)
KIF5BGeneProduct450390 (Entrez Gene)
LIPEGeneProduct
MAP2K1GeneProduct450188 (Entrez Gene)
MAP2K2GeneProduct456390 (Entrez Gene)
MAP2K3GeneProduct454515 (Entrez Gene)
MAP2K4GeneProduct455065 (Entrez Gene)
MAP2K5GeneProduct453532 (Entrez Gene)
MAP2K6GeneProduct468310 (Entrez Gene)
MAP2K7GeneProduct743199 (Entrez Gene)
MAP3K1GeneProduct
MAP3K10GeneProduct
MAP3K11GeneProduct451326 (Entrez Gene)
MAP3K12GeneProduct451940 (Entrez Gene)
MAP3K13GeneProduct737524 (Entrez Gene)
MAP3K14GeneProduct
MAP3K2GeneProduct736244 (Entrez Gene)
MAP3K3GeneProduct
MAP3K4GeneProduct
MAP3K5GeneProduct463023 (Entrez Gene)
MAP3K6GeneProduct456674 (Entrez Gene)
MAP3K7GeneProduct462888 (Entrez Gene)
MAP3K8GeneProduct450384 (Entrez Gene)
MAP3K9GeneProduct467498 (Entrez Gene)
MAP4K1GeneProduct
MAP4K2GeneProduct451301 (Entrez Gene)
MAP4K3GeneProduct459173 (Entrez Gene)
MAP4K4GeneProduct459459 (Entrez Gene)
MAP4K5GeneProduct467451 (Entrez Gene)
MAPK10GeneProduct461358 (Entrez Gene)
MAPK11GeneProduct
MAPK12GeneProduct
MAPK13GeneProduct462644 (Entrez Gene)
MAPK14GeneProduct450161 (Entrez Gene)
MAPK1GeneProduct458680 (Entrez Gene)
MAPK3GeneProduct454037 (Entrez Gene)
MAPK4GeneProduct
MAPK6GeneProduct453439 (Entrez Gene)
MAPK7GeneProduct
MAPK8GeneProduct450445 (Entrez Gene)
MAPK9GeneProduct462336 (Entrez Gene)
MINK1GeneProduct454455 (Entrez Gene)
MYO1CGeneProduct750403 (Entrez Gene)
PDPK1GeneProduct
PFKLGeneProduct458602 (Entrez Gene)
PFKMGeneProduct451863 (Entrez Gene)
PIK3C2AGeneProduct451052 (Entrez Gene)
PIK3C2GGeneProduct
PIK3C3GeneProduct455385 (Entrez Gene)
PIK3CAGeneProduct460858 (Entrez Gene)
PIK3CBGeneProduct
PIK3CDGeneProduct457922 (Entrez Gene)
PIK3CGGeneProduct463649 (Entrez Gene)
PIK3R1GeneProduct461836 (Entrez Gene)
PIK3R2GeneProduct455855 (Entrez Gene)
PIK3R3GeneProduct
PIK3R4GeneProduct460692 (Entrez Gene)
PPP1R3AGeneProduct463666 (Entrez Gene)
PRKAA1GeneProduct
PRKAA2GeneProduct741802 (Entrez Gene)
PRKCAGeneProduct
PRKCB1GeneProduct
PRKCDGeneProduct
PRKCHGeneProduct746068 (Entrez Gene)
PRKCIGeneProduct450143 (Entrez Gene)
PRKCQGeneProduct450288 (Entrez Gene)
PRKCZGeneProduct743533 (Entrez Gene)
PSCD3GeneProduct
PTENGeneProduct466142 (Entrez Gene)
PTPN11GeneProduct
PTPN1GeneProduct469970 (Entrez Gene)
PTPRFGeneProduct456828 (Entrez Gene)
RAB4AGeneProduct
RAC1GeneProduct
RAC2GeneProduct742575 (Entrez Gene)
RAF1GeneProduct460182 (Entrez Gene)
RAPGEF1GeneProduct464812 (Entrez Gene)
RHEBGeneProduct463880 (Entrez Gene)
RHOJGeneProduct452960 (Entrez Gene)
RHOQGeneProduct740809 (Entrez Gene)
RHOXF2GeneProduct473763 (Entrez Gene)
RPS6KA1GeneProduct
RPS6KA2GeneProduct
RPS6KA3GeneProduct
RPS6KA4GeneProduct451715 (Entrez Gene)
RPS6KA5GeneProduct739162 (Entrez Gene)
RPS6KA6GeneProduct
RPS6KB1GeneProduct468426 (Entrez Gene)
RPS6KB2GeneProduct746903 (Entrez Gene)
RRADGeneProduct741038 (Entrez Gene)
SGKGeneProduct
SGK2GeneProduct740699 (Entrez Gene)
SGK3GeneProduct464217 (Entrez Gene)
SH2B2GeneProduct741557 (Entrez Gene)
SHC1GeneProduct457351 (Entrez Gene)
SHC2GeneProduct
SHC3GeneProduct450176 (Entrez Gene)
SLC2A1GeneProduct
SLC2A4GeneProduct468443 (Entrez Gene)
SNAP23GeneProduct453365 (Entrez Gene)
SNAP25GeneProduct458096 (Entrez Gene)
SNX26GeneProduct
SOCS1GeneProduct737070 (Entrez Gene)
SOCS3GeneProduct454921 (Entrez Gene)
SORBS1GeneProduct450628 (Entrez Gene)
SOS1GeneProduct459171 (Entrez Gene)
SOS2GeneProduct
SRFGeneProduct462709 (Entrez Gene)
STX4AGeneProduct
STXBP1GeneProduct
STXBP2GeneProduct741963 (Entrez Gene)
STXBP3GeneProduct737947 (Entrez Gene)
STXBP4GeneProduct468411 (Entrez Gene)
TBC1D4GeneProduct467286 (Entrez Gene)
TRIB3GeneProduct
TSC1GeneProduct464818 (Entrez Gene)
TSC2GeneProduct468086 (Entrez Gene)
VAMP2GeneProduct747237 (Entrez Gene)
XBP1GeneProduct458735 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP847"
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