Complement and coagulation cascades (Pan troglodytes)

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Antibody/antigencomplexCell lysisClotFibrinolytic systemCoagulation CascadeMuscle contraction,Chemotaxis,Phagocyte recruitmentInflammation, etc.Extrinsic pathwayDegredationMediatorsC4b/2aC3ConvertaseKinin kallikrein systemC3aVascular injuryCell adhesion,migration,profileration, etcComplement CascadeZymosan,insulin, etc.C3b/BbC3b/4b, C3b, C3dClassical PathwayC4aCell adhesion,migration,profileration, etcmembrane attack complexCollagen,basement membrane,activated platelets, etc.C5aLectin PathwayThrombinfibrin degredationproductsAlternative PathwayC3bCross-linkedfibrin polymerPlatelet, monocyte,lymphocyte,endothelial cells,smooth muscle cellsactivation, etcC6PLGF8KLKB1CFHPLAUF10Daf1C3AR1MASP2FGB109821CFIA2MPLAURF2SERPING1CD59AC5AR1F2RPLATTFPIMASP1ADNPROS1F13BBradykininF7C8GVWFC3C4PROCKNG1F9SERPINE1CR1SERPINA1F3C4BPCD46SERPIND1BDKRB1F5HcMBL1C1RCRRYSERPINF2SERPINA5C1SC1QCC1QAC9Daf2CPB2C1QBC2Fibrin monomerTHBDCR2SERPINC1F12H2-BFC7


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/dbget-bin/get pathway?org name=mmu&mapno=04610
GenMAPP remarks 
Adapted from KEGG (see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP558(r22582) with a 58% conversion rate.

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Ontology Terms

 

Bibliography

  1. ''''; https://www.genome.jp/dbget-bin/www_bget?pathway+map04610,

History

View all...
CompareRevisionActionTimeUserComment
122636view17:53, 22 April 2022Khanspers
122583view10:00, 18 April 2022EweitzModified title
89201view04:00, 23 August 2016AriuttaOntology Term : 'hemostasis pathway' added !
89200view04:00, 23 August 2016AriuttaOntology Term : 'coagulation cascade pathway' added !
89199view04:00, 23 August 2016AriuttaOntology Term : 'complement system pathway' added !
71692view19:42, 17 October 2013MaintBotAutomated update of data sources
69308view18:43, 8 July 2013MaintBotUpdated to 2013 gpml schema
41618view02:02, 2 March 2011MaintBotRemoved redundant pathway information and comments
38707view19:28, 23 September 2010AlexanderPico
34346view22:20, 9 December 2009MaintBotAutomatic update of empty xrefs
33587view09:51, 1 December 2009MaintBotRemoved group label
31610view22:13, 13 August 2009MaintBotFixed text labels
30507view21:44, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A2MGeneProduct465372 (Entrez Gene)
ADNGeneProduct
BDKRB1GeneProduct
BradykininGeneProduct
C1QAGeneProduct749231 (Entrez Gene)
C1QBGeneProduct469214 (Entrez Gene)
C1QCGeneProduct456612 (Entrez Gene)
C1RGeneProduct466939 (Entrez Gene)
C1SGeneProduct451808 (Entrez Gene)
C2GeneProduct
C3GeneProduct455644 (Entrez Gene)
C3AR1GeneProduct466942 (Entrez Gene)
C4GeneProduct
C4BPGeneProduct
C5AR1GeneProduct468931 (Entrez Gene)
C6GeneProduct449612 (Entrez Gene)
C7GeneProduct738238 (Entrez Gene) MGI:88235 LL:109828
C8GGeneProduct
C9GeneProduct
CD46GeneProduct469663 (Entrez Gene)
CD59AGeneProduct
CFHGeneProduct
CFIGeneProduct
CPB2GeneProduct452582 (Entrez Gene)
CR1GeneProduct449643 (Entrez Gene)
CR2GeneProduct457690 (Entrez Gene)
CRRYGeneProduct
Daf1GeneProduct
Daf2GeneProduct
F10GeneProduct452679 (Entrez Gene)
F12GeneProduct462304 (Entrez Gene)
F13BGeneProduct735857 (Entrez Gene)
F2GeneProduct451158 (Entrez Gene)
F2RGeneProduct471510 (Entrez Gene)
F3GeneProduct457038 (Entrez Gene)
F5GeneProduct
F7GeneProduct744785 (Entrez Gene)
F8GeneProduct
F9GeneProduct465887 (Entrez Gene)
FGBGeneProduct461558 (Entrez Gene)
Fibrin monomerGeneProduct
H2-BFGeneProduct
HcGeneProduct
KLKB1GeneProduct
KNG1GeneProduct460916 (Entrez Gene)
MASP1GeneProduct
MASP2GeneProduct736039 (Entrez Gene)
MBL1GeneProduct
PLATGeneProduct472748 (Entrez Gene)
PLAUGeneProduct
PLAURGeneProduct450103 (Entrez Gene)
PLGGeneProduct463117 (Entrez Gene)
PROCGeneProduct459593 (Entrez Gene)
PROS1GeneProduct460533 (Entrez Gene)
SERPINA1GeneProduct467541 (Entrez Gene)
SERPINA5GeneProduct
SERPINC1GeneProduct457528 (Entrez Gene)
SERPIND1GeneProduct745390 (Entrez Gene)
SERPINE1GeneProduct472467 (Entrez Gene)
SERPINF2GeneProduct
SERPING1GeneProduct
TFPIGeneProduct470603 (Entrez Gene)
THBDGeneProduct469898 (Entrez Gene)
VWFGeneProduct451773 (Entrez Gene)
109821GeneProduct

Annotated Interactions

No annotated interactions
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