G13 signaling pathway (Pan troglodytes)
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Cytokinesis
Stress Fiber
Disappearance
Anti-Apoptotic
Disassembly of Actin
Actin Reorganization
Cell-Cell Adhesion

G
13
Actin Polymerization
Filopodia Formation

Actin 
Polymerization
Membrane
Ruffling
Activated Rho A
Contraction & Actin-Myosin
Interaction, Focal Adhesion
Stress Fiber Contraction
PIK3CA
ROCK2
p140 Sra-1
PAK3
DIAPH1
LIMK1
WAS
PPP1CB
ARHGDIB
CIT
PFN1
PIK3CB
PIK3CD
MYL1
TNK2
CALM1
MAP3K4
WASL
RHPN2
ROCK1
IQGAP2
CFL2
PKN1
MAPK10
PIP4K2A
RPS6KB1
ARHGDIG
PIK3R2
IQGAP1
MYBPH
GNA13
RTKN
CFL1
SH3RF1
ARHGEF1
RAC1
CDC42
RHOA
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP524(r21780)
with a 73% conversion rate.
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
117394
view
10:34, 21 May 2021
Eweitz
Modified title
95756
view
14:07, 19 January 2018
Mkutmon
Homology conversion update
72020
view
12:40, 24 October 2013
Mkutmon
fixed unconnected lines
71676
view
19:41, 17 October 2013
MaintBot
Automated update of data sources
69269
view
18:38, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67279
view
10:30, 26 June 2013
Christine Chichester
Ontology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
62741
view
03:34, 2 May 2013
MaintBot
Updated UniProt data source
41577
view
02:00, 2 March 2011
MaintBot
Removed redundant pathway information and comments
35419
view
10:42, 12 February 2010
Thomas
Modified description
35418
view
10:39, 12 February 2010
Thomas
removed braces, fixed labels, added literature
34305
view
22:06, 9 December 2009
MaintBot
Automatic update of empty xrefs
33595
view
09:55, 1 December 2009
MaintBot
Removed group label
32477
view
17:40, 15 August 2009
MaintBot
Fixed text labels
31615
view
22:16, 13 August 2009
MaintBot
Fixed text labels
30514
view
21:47, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ARHGDIB
GeneProduct
742002 (Entrez Gene)
ARHGDIG
GeneProduct
749799 (Entrez Gene)
ARHGEF1
GeneProduct
CALM1
GeneProduct
CDC42
GeneProduct
456609 (Entrez Gene)
CFL1
GeneProduct
745772 (Entrez Gene)
CFL2
GeneProduct
452853 (Entrez Gene)
CIT
GeneProduct
452298 (Entrez Gene)
DIAPH1
GeneProduct
GNA13
GeneProduct
454827 (Entrez Gene)
IQGAP1
GeneProduct
467762 (Entrez Gene)
IQGAP2
GeneProduct
461801 (Entrez Gene)
LIMK1
GeneProduct
463466 (Entrez Gene)
MAP3K4
GeneProduct
MAPK10
GeneProduct
461358 (Entrez Gene)
MYBPH
GeneProduct
457639 (Entrez Gene)
MYL1
GeneProduct
459915 (Entrez Gene)
PAK3
GeneProduct
450118 (Entrez Gene)
PFN1
GeneProduct
PIK3CA
GeneProduct
460858 (Entrez Gene)
PIK3CB
GeneProduct
PIK3CD
GeneProduct
457922 (Entrez Gene)
P42338
PIK3R2
GeneProduct
455855 (Entrez Gene)
PIP4K2A
GeneProduct
742458 (Entrez Gene)
PKN1
GeneProduct
455785 (Entrez Gene)
PPP1CB
GeneProduct
459118 (Entrez Gene)
RAC1
GeneProduct
RHOA
GeneProduct
461014 (Entrez Gene)
RHPN2
GeneProduct
742833 (Entrez Gene)
ROCK1
GeneProduct
455326 (Entrez Gene)
S69211
ROCK2
GeneProduct
470307 (Entrez Gene)
BAA31594
RPS6KB1
GeneProduct
468426 (Entrez Gene)
A41687
RTKN
GeneProduct
459334 (Entrez Gene)
SH3RF1
GeneProduct
461598 (Entrez Gene)
Posh
TNK2
GeneProduct
S33596
WAS
GeneProduct
WASL
GeneProduct
463688 (Entrez Gene)
p140 Sra-1
GeneProduct
Annotated Interactions
No annotated interactions
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Discussion
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View approved pathways at the new wikipathways.org.Quality Tags
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No annotated interactions