G1 to S cell cycle control (Pan troglodytes)

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pRbpG1 CyclinDependant CyclasesTTTCC/GCGCorigin recognition complexCell cycle DNA replication genesphosphorylation of proteinsinvolved in G1/S transitionG1/S transition CyclinDependent KinasesppG1/S Cell Cycledp1euCheckpointG1/S transition PhaseDegradationcakinactiveCyclin EsDNA polymeraseseG2 Phase-M phaseuG1 PhasebbppE2fDNA replicationuCyclin DsTFDP1CDK7CCNA1RB1E2F2CCND1CCNE1CCNB1CDK6E2F5RPA3ORC4LTFDP1ORC6LCyclinDMCM2RB1MYCMCM7RBL1ORC5LMNAT1CCND2CDK4CREB1TFDP2RHOXF2ATMCyclinDWEE1CDKN1ACDKN2BCDKN2ACdkRPA1CCND3PRIM1MCM5CREB3CDC25ACDK6E2F3CCNG2POLE2MYT1TP53CDKN1CCCNE1E2F6MCM6CCNHPCNACDKN2CCDKN1BCdkE2F4CDK4MDM2CREB3L3ORC1LPOLECDKN2DCCNE1RPA2E2fPOLA2CCNE2PRIM2ACREB3L1CREB3L4ORC2LE2F1CDK7RB1MCM3CDKATF6BE2fMCM4GADD45AORC3LCDKCDK2CDC45LTP53RHOXF2


Description

No description

Comments

GenMAPP notes 
Adapted from http://www.genomeknowledge.org/, and Maeda et al. Journal of Invest Dermatol. 2002. 119:22-26.
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP45(r20771) with a 81% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Maeda T, Hanna AN, Sim AB, Chua PP, Chong MT, Tron VA; ''GADD45 regulates G2/M arrest, DNA repair, and cell death in keratinocytes following ultraviolet exposure.''; J Invest Dermatol, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
95751view13:54, 19 January 2018MkutmonHomology conversion update
69254view18:36, 8 July 2013MaintBotUpdated to 2013 gpml schema
67272view10:29, 26 June 2013Christine ChichesterOntology Term : 'G1/S DNA damage checkpoint pathway' added !
48163view20:20, 9 May 2012MaintBotUpdating from human to fix xrefs
41561view01:59, 2 March 2011MaintBotRemoved redundant pathway information and comments
35832view22:17, 17 February 2010KhanspersAdded lit ref
35831view22:16, 17 February 2010KhanspersModified description
34291view22:01, 9 December 2009MaintBotAutomatic update of empty xrefs
33608view09:59, 1 December 2009MaintBotRemoved group label
31622view22:19, 13 August 2009MaintBotFixed text labels
30528view21:52, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATF6BGeneProduct745411 (Entrez Gene)
ATMGeneProduct451530 (Entrez Gene)
CCNA1GeneProduct467260 (Entrez Gene)
CCNB1GeneProduct461835 (Entrez Gene)
CCND1GeneProduct
CCND2GeneProduct747123 (Entrez Gene)
CCND3GeneProduct462689 (Entrez Gene)
CCNE1GeneProduct455914 (Entrez Gene)
CCNE2GeneProduct464292 (Entrez Gene)
CCNG2GeneProduct461229 (Entrez Gene)
CCNHGeneProduct739351 (Entrez Gene)
CDC25AGeneProduct460341 (Entrez Gene)
CDC45LGeneProduct458651 (Entrez Gene)
CDKGeneProduct
CDK2GeneProduct467032 (Entrez Gene)
CDK4GeneProduct452025 (Entrez Gene)
CDK6GeneProduct746968 (Entrez Gene)
CDK7GeneProduct462378 (Entrez Gene)
CDKN1AGeneProduct747442 (Entrez Gene)
CDKN1BGeneProduct466947 (Entrez Gene)
CDKN1CGeneProduct
CDKN2AGeneProduct465021 (Entrez Gene)
CDKN2BGeneProduct
CDKN2CGeneProduct469319 (Entrez Gene)
CDKN2DGeneProduct745942 (Entrez Gene)
CREB1GeneProduct459901 (Entrez Gene)
CREB3GeneProduct
CREB3L1GeneProduct451704 (Entrez Gene)
CREB3L3GeneProduct468672 (Entrez Gene)
CREB3L4GeneProduct457341 (Entrez Gene)
CdkGeneProduct
CyclinDGeneProduct
E2F1GeneProduct
E2F2GeneProduct469153 (Entrez Gene)
E2F3GeneProduct
E2F4GeneProduct454158 (Entrez Gene)
E2F5GeneProduct747256 (Entrez Gene)
E2F6GeneProduct470148 (Entrez Gene)
E2fGeneProduct
GADD45AGeneProduct456929 (Entrez Gene)
MCM2GeneProduct460668 (Entrez Gene)
MCM3GeneProduct462763 (Entrez Gene)
MCM4GeneProduct472757 (Entrez Gene)
MCM5GeneProduct458790 (Entrez Gene)
MCM6GeneProduct741695 (Entrez Gene)
MCM7GeneProduct472460 (Entrez Gene)
MDM2GeneProduct742141 (Entrez Gene)
MNAT1GeneProduct452954 (Entrez Gene)
MYCGeneProduct464393 (Entrez Gene)
MYT1GeneProduct
ORC1LGeneProduct456857 (Entrez Gene)
ORC2LGeneProduct459868 (Entrez Gene)
ORC3LGeneProduct462876 (Entrez Gene)
ORC4LGeneProduct459647 (Entrez Gene)
ORC5LGeneProduct463636 (Entrez Gene)
ORC6LGeneProduct465140 (Entrez Gene)
PCNAGeneProduct458081 (Entrez Gene)
POLA2GeneProduct451318 (Entrez Gene)
POLE2GeneProduct452888 (Entrez Gene)
POLEGeneProduct467165 (Entrez Gene)
PRIM1GeneProduct746924 (Entrez Gene)
PRIM2AGeneProduct
RB1GeneProduct452715 (Entrez Gene)
RBL1GeneProduct735916 (Entrez Gene)
RHOXF2GeneProduct473763 (Entrez Gene)
RPA1GeneProduct454414 (Entrez Gene)
RPA2GeneProduct456680 (Entrez Gene)
RPA3GeneProduct472290 (Entrez Gene)
TFDP1GeneProduct465967 (Entrez Gene)
TFDP2GeneProduct460743 (Entrez Gene)
TP53GeneProduct455214 (Entrez Gene)
WEE1GeneProduct466440 (Entrez Gene)

Annotated Interactions

No annotated interactions
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