Complement and coagulation cascades (Mus musculus)

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DegradationThrombinPlatelet, monocyte,lymphocyte,endothelial cells,smooth muscle cells,activation, etc.C3aC3bInflammation, etc.membrane attack complexClotCell adhesion,migration,proliferation, etc.fibrin degradationproductsC3b/4b, C3b, C3dVascular injuryMediatorsPhagocyte recruitmentC5aCross-linkedLectin PathwayCell adhesion,migration,proliferation, etc.Coagulation CascadeFibrinolytic systemAlternative PathwayKinin kallikrein systemC4b/2aC4aC3b/Bbfibrin polymerChemotaxis,Muscle contraction,C3ConvertaseCollagen,basement membrane,activated platelets etc.Antibody/antigencomplexFibrinmonomerComplement CascadeClassical PathwayExtrinsic pathwayZymosaninsulin etc.Cell lysisPros1Cr1HcF2rBdkrb1F12C2PlgCfiMasp2Kng1ThbdC4Daf1C7C1sPlauC1qgF11F10Serpina1McpSerpina5C3C9Masp1BradykininF5VwfDaf2Serpinf2AdnC1qbSerpine1C1qaC6Proc1700013L23RikKlkb1C5r1Cpb2F3PlaurF8H2-BfSerping1Cr2F7TfpiSerpind1CfhC1rFgbPlatF13bCrryF2C4bpC3ar1Serpinc1A2mCd59aMbl1F9


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/dbget-bin/get pathway?org name=mmu&mapno=04610
GenMAPP remarks 
Adapted from KEGG (see notes)

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
122582view10:00, 18 April 2022EweitzModified title
114008view14:51, 17 December 2020Fehrhartconnected lines
109409view18:14, 16 March 2020L DupuisFixed interactions
106896view13:37, 17 September 2019MaintBotHMDB identifier normalization
104990view04:21, 28 June 2019Khanspersremoved KEGG comments
71733view20:17, 17 October 2013MaintBotAutomated update of data sources
69115view18:13, 8 July 2013MaintBotUpdated to 2013 gpml schema
67784view15:12, 26 June 2013DdiglesOntology Term : 'complement system pathway' added !
67124view10:09, 26 June 2013Christine ChichesterOntology Term : 'coagulation cascade pathway' added !
41301view00:23, 2 March 2011MaintBotRemoved redundant pathway information and comments
38703view19:27, 23 September 2010AlexanderPico
33690view22:22, 3 December 2009KhanspersAdded connectors
33689view22:17, 3 December 2009KhanspersPeriodical save, work in progress
33688view22:06, 3 December 2009KhanspersPeriodical save, work in progress
33687view21:56, 3 December 2009KhanspersPeriodical save, work in progress
22601view13:45, 14 November 2008ThomasChanged pathway title (was duplicate of WP200)
21624view11:32, 14 November 2008MaintBot[[Pathway:Mus musculus:Complement and Coagulation Cascades KEGG]] moved to [[Pathway:WP449]]: Moved to stable identifier
7974view13:46, 7 January 2008MaintBot[[Pathway:Mouse:Complement and Coagulation Cascades KEGG]] moved to [[Pathway:Mus musculus:Complement and Coagulation Cascades KEGG]]: Renaming species
7611view16:04, 18 December 2007MaintBotfixed category names
7468view12:42, 4 November 2007MaintBotAdded categories to GPML
6428view22:18, 22 May 2007169.230.77.174gpml file for [[Mouse:Complement_and_Coagulation_Cascades_KEGG]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1700013L23RikGeneProduct69379 (Entrez Gene)
A2mGeneProduct232345 (Entrez Gene)
AdnGeneProduct11537 (Entrez Gene)
Bdkrb1GeneProduct12061 (Entrez Gene)
BradykininMetaboliteHMDB04246 (HMDB)
C1qaGeneProduct12259 (Entrez Gene)
C1qbGeneProduct12260 (Entrez Gene)
C1qgGeneProduct12262 (Entrez Gene)
C1rGeneProduct50909 (Entrez Gene)
C1sGeneProduct50908 (Entrez Gene)
C2GeneProduct12263 (Entrez Gene)
C3GeneProduct12266 (Entrez Gene)
C3ar1GeneProduct12267 (Entrez Gene)
C4GeneProduct12268 (Entrez Gene)
C4bpGeneProduct12269 (Entrez Gene)
C5r1GeneProduct12273 (Entrez Gene)
C6GeneProduct12274 (Entrez Gene)
C7GeneProduct109828 (Entrez Gene) MGI:88235 LL:109828
C9GeneProduct12279 (Entrez Gene)
Cd59aGeneProduct12509 (Entrez Gene)
CfhGeneProduct12628 (Entrez Gene)
CfiGeneProduct12630 (Entrez Gene)
Cpb2GeneProduct56373 (Entrez Gene)
Cr1GeneProduct
Cr2GeneProduct12902 (Entrez Gene)
CrryGeneProduct12946 (Entrez Gene)
Daf1GeneProduct13136 (Entrez Gene)
Daf2GeneProduct13137 (Entrez Gene)
F10GeneProduct14058 (Entrez Gene)
F11GeneProduct109821 (Entrez Gene)
F12GeneProduct58992 (Entrez Gene)
F13bGeneProduct14060 (Entrez Gene)
F2GeneProduct14061 (Entrez Gene)
F2rGeneProduct14062 (Entrez Gene)
F3GeneProduct14066 (Entrez Gene)
F5GeneProduct14067 (Entrez Gene)
F7GeneProduct14068 (Entrez Gene)
F8GeneProduct14069 (Entrez Gene)
F9GeneProduct14071 (Entrez Gene)
FgbGeneProduct110135 (Entrez Gene)
H2-BfGeneProduct14962 (Entrez Gene)
HcGeneProduct15139 (Entrez Gene)
Klkb1GeneProduct16621 (Entrez Gene)
Kng1GeneProduct16644 (Entrez Gene)
Masp1GeneProduct17174 (Entrez Gene)
Masp2GeneProduct17175 (Entrez Gene)
Mbl1GeneProduct17194 (Entrez Gene)
McpGeneProduct17221 (Entrez Gene)
PlatGeneProduct18791 (Entrez Gene)
PlauGeneProduct18792 (Entrez Gene)
PlaurGeneProduct18793 (Entrez Gene)
PlgGeneProduct18815 (Entrez Gene)
ProcGeneProduct19123 (Entrez Gene)
Pros1GeneProduct19128 (Entrez Gene)
Serpina1GeneProduct20699 (Entrez Gene)
Serpina5GeneProduct268591 (Entrez Gene)
Serpinc1GeneProduct11905 (Entrez Gene)
Serpind1GeneProduct15160 (Entrez Gene)
Serpine1GeneProduct18787 (Entrez Gene)
Serpinf2GeneProduct18816 (Entrez Gene)
Serping1GeneProduct12258 (Entrez Gene)
TfpiGeneProduct21788 (Entrez Gene)
ThbdGeneProduct21824 (Entrez Gene)
VwfGeneProduct22371 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP449"
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