Valine, leucine and isoleucine degradation (Caenorhabditis elegans)

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Valine, leucine and isoleucine biosynthesispccb-1acdh-8tag-173L-Isoleucineech-3Acetoacetic acidech-5T08B2.7K09H11.1S-3-Methyl-2-oxopentanoic acid2-Methylacetoacetyl-CoALipoamide-EB0272.3ech-2bcat-1T08B2.7bcat-1Dihydrolipoamide-Etag-173ech-7ech-2acdh-3ech-7Succinyl-CoAacdh-7ZK669.4L-Valineech-9ech-6ZK669.4TransketolaseAcetyl-CoAacdh-10ech-1Transketolaseacdh-8(S)-3-Hydroxyisobutyryl-CoAS-(2-Methylbutanoyl)-dihydrolipoamide-EK09H11.1Y44A6D.5S-2-Methylbutanoyl-CoAF53A2.72-Methyl-1-hydroxybutyl-ThPPacdh-3F54C8.1Acetoacetyl-CoAard-1Propionyl-CoATiglyl-CoAech-5Y44A6D.5TransketolaseLLC1.3TransketolaseLipoamide-E3-Aminoisobutanoic acidS-(2-Methylpropionyl)-dihydrolipoamide-Egta-1ech-6B0303.3Methylmalonic acidtag-173a-Ketoisovaleric acidech-1hacd-1(S)-3-Hydroxyisobutyric acidacdh-7Thiamine pyrophosphateMethacrylyl-CoAS-Methylmalonic acid semialdehydeS-Methylmalonyl-CoAtag-173Thiamine pyrophosphatepcca-12-Methyl-3-hydroxybutyryl-CoADihydrolipoamide-ELLC1.3ech-8acdh-10R-Methylmalonyl-CoA2-Methyl-1-hydroxypropyl-ThPPech-3Isobutyryl-CoA


Description

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History

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CompareRevisionActionTimeUserComment
34744view22:49, 13 January 2010KhanspersDeleted pathway: duplicate
33726view15:41, 8 December 2009Pieter Giesbertzfixed datapoints from KEGG
33725view15:29, 8 December 2009Pieter GiesbertzPeriodical save, work in progress
33724view15:19, 8 December 2009Pieter GiesbertzPeriodical save, work in progress
33723view15:09, 8 December 2009Pieter GiesbertzPeriodical save, work in progress
33722view14:59, 8 December 2009Pieter Giesbertzmanually improving KEGG pathway
33719view13:39, 8 December 2009Pieter Giesbertzmanually improving KEGG pathway
33718view12:48, 8 December 2009Pieter GiesbertzNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
(S)-3-Hydroxyisobutyric acidMetaboliteHMDB00023 (HMDB)
(S)-3-Hydroxyisobutyryl-CoAMetaboliteHMDB01052 (HMDB)
2-Methyl-1-hydroxybutyl-ThPPMetaboliteHMDB12310 (HMDB)
2-Methyl-1-hydroxypropyl-ThPPMetaboliteHMDB06866 (HMDB)
2-Methyl-3-hydroxybutyryl-CoAMetaboliteHMDB01356 (HMDB)
2-Methylacetoacetyl-CoAMetaboliteHMDB01157 (HMDB)
3-Aminoisobutanoic acidMetaboliteHMDB03911 (HMDB)
Acetoacetic acidMetaboliteAcetoacetic acid (Wikipedia)
Acetoacetyl-CoAMetaboliteHMDB01484 (HMDB)
Acetyl-CoAMetaboliteHMDB01206 (HMDB)
B0272.3GeneProductB0272.3 (Ensembl C. elegans)
B0303.3GeneProductB0303.3 (Ensembl C. elegans)
Dihydrolipoamide-EMetaboliteHMDB06879 (HMDB)
F53A2.7GeneProductF53A2.7 (Ensembl C. elegans)
F54C8.1GeneProduct186222 (Entrez Gene)
Isobutyryl-CoAMetaboliteHMDB01243 (HMDB)
K09H11.1GeneProduct178962 (Entrez Gene)
L-IsoleucineMetaboliteHMDB00172 (HMDB)
L-ValineMetaboliteHMDB00883 (HMDB)
LLC1.3GeneProductLLC1.3 (Ensembl C. elegans)
Lipoamide-EMetaboliteHMDB06877 (HMDB)
Methacrylyl-CoAMetaboliteHMDB01011 (HMDB)
Methylmalonic acidMetaboliteHMDB00202 (HMDB)
Propionyl-CoAMetaboliteHMDB01275 (HMDB)
R-Methylmalonyl-CoAMetaboliteHMDB02255 (HMDB)
S-(2-Methylbutanoyl)-dihydrolipoamide-EMetaboliteHMDB06869 (HMDB)
S-(2-Methylpropionyl)-dihydrolipoamide-EMetaboliteHMDB06868 (HMDB)
S-2-Methylbutanoyl-CoAMetabolite47205293 (PubChem)
S-3-Methyl-2-oxopentanoic acidMetabolite3940 (PubChem)
S-Methylmalonic acid semialdehydeMetaboliteHMDB02217 (HMDB)
S-Methylmalonyl-CoAMetaboliteHMDB02310 (HMDB)
Succinyl-CoAMetaboliteHMDB01022 (HMDB)
T08B2.7GeneProductT08B2.7 (Ensembl C. elegans)
Thiamine pyrophosphateMetaboliteHMDB01372 (HMDB)
Tiglyl-CoAMetaboliteHMDB02054 (HMDB)
TransketolaseGeneProductY39E4A.3 (WormBase) Original kegg element: gene;12;cel:F27D4.5 cel:Y39E4A.3
Y44A6D.5GeneProduct180361 (Entrez Gene)
ZK669.4GeneProduct174279 (Entrez Gene)
a-Ketoisovaleric acidMetaboliteHMDB00019 (HMDB)
acdh-10GeneProductT08G2.3 (WormBase) Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5
acdh-3GeneProductK06A5.6 (WormBase) Original kegg element: gene;41;cel:K06A5.6
acdh-7GeneProductT25G12.5 (WormBase) Original kegg element: gene;58;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5
acdh-8GeneProductK05F1.3 (WormBase)
ard-1GeneProductF01G4.2 (WormBase)
bcat-1GeneProductK02A4.1 (WormBase) Original kegg element: gene;37;cel:K02A4.1 cel:Y44A6D.5
ech-1GeneProductC29F3.1 (WormBase)
ech-2GeneProductF38H4.8 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-3GeneProductF43H9.1 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-5GeneProductF56B3.5 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-6GeneProductT05G5.6 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-7GeneProductY105E8A.4 (WormBase) Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4
ech-8GeneProductF01G10.2 (WormBase)
ech-9GeneProductF01G10.3 (WormBase)
gta-1GeneProductK04D7.3 (WormBase)
hacd-1GeneProductR09B5.6 (WormBase)
pcca-1GeneProductF27D9.5 (WormBase)
pccb-1GeneProductF52E4.1 (WormBase)
tag-173GeneProductF27D4.5 (WormBase) Original kegg element: gene;43;cel:F27D4.5 cel:Y39E4A.3

Annotated Interactions

No annotated interactions

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