Cytokines and inflammatory response (Bos taurus)
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Inflammatory Response
B Cell
Fibroblasts
Macrophage
Th
Hematopoietic Stem Cell
Th
Endothelial Cells
antigen
Hematopoiesis
B Cell
Th
B Cell
T-helper
NK cell
Plasma Cell
MHC II
Eos
Tc
Eos
Tc
Mast Cell
Neutrophil
B Cell
Lymphocyte Activated
Killer Cells (LAK)
Eos
T-helper
antibodies
TCR
Hypothalamus
(fever)
Clonal expansion of T cells
Tc
CXCL2
IL1B
PDGFA
IL12
IL4
IL4
IL3
IL1A
IL15
IL3
CSF1
IL13
IFNG
IL4
IL15
IL1A
IL2
IL12B
TNF
IL10
TNF
IL1B
CSF3
IL6
IL1A
IL4
IL12B
TNF
IL10
IL6
TGFB1
IFNB1
IL7
TGFB1
IFNG
IL1B
TRB
CXCL1
IL2
IL10
IL6
IL4
IL2
IL10
CD4
TNF
IL6
BOLA-DRA
TRA
TNF
TNF
IL5
CSF2
IL1A
IFNG
IFN1@
IL2
HLA-DRB1
IL15
IL1B
IL6
IL3
IFN1@
IL5
IL11
TGFB1
IL2
TNF
IL1A
IL2
IL1B
IL13
CSF2
IL3
IL2
Description
See BioCarta version:
http://www.biocarta.com/pathfiles/h_inflamPathway.asp
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP530(r21794)
with a 74% conversion rate.
Try the New WikiPathways
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Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
Kataoka T; ''Chemical biology of inflammatory cytokine signaling.''; J Antibiot (Tokyo), 2009
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
117494
view
11:03, 21 May 2021
Eweitz
Modified title
111165
view
09:28, 21 July 2020
Egonw
Made another pathway clickable
86911
view
08:03, 14 July 2016
Mkutmon
Ontology Term : 'inflammatory response pathway' added !
86910
view
08:03, 14 July 2016
Mkutmon
Ontology Term : 'PW:0000029' removed !
80658
view
15:21, 30 June 2015
Mkutmon
homology conversion
70163
view
00:27, 13 July 2013
AlexanderPico
Modified title
67132
view
10:10, 26 June 2013
Christine Chichester
Ontology Term : 'inflammatory response pathway' added !
63344
view
22:21, 9 May 2013
MaintBot
Updated to 2013 gpml schema
40518
view
19:29, 1 March 2011
MaintBot
Removed redundant pathway information and comments
38656
view
12:56, 23 September 2010
FerryJagers
fixed database @ linked pathway
38649
view
12:37, 23 September 2010
FerryJagers
Linked pathway
38648
view
12:34, 23 September 2010
FerryJagers
Linked Inflammatory Response Pathway
35251
view
19:57, 11 February 2010
Thomas
added literature
33761
view
00:03, 9 December 2009
MaintBot
Automatic update of empty xrefs
33638
view
10:06, 1 December 2009
MaintBot
Removed group label
31643
view
22:27, 13 August 2009
MaintBot
Fixed text labels
30566
view
22:04, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
BOLA-DRA
GeneProduct
506214 (Entrez Gene)
CD4
GeneProduct
407098 (Entrez Gene)
CSF1
GeneProduct
281094 (Entrez Gene)
CSF2
GeneProduct
281095 (Entrez Gene)
CSF3
GeneProduct
281096 (Entrez Gene)
CXCL1
GeneProduct
CXCL2
GeneProduct
613667 (Entrez Gene)
HLA-DRB1
GeneProduct
IFN1@
GeneProduct
281236 (Entrez Gene)
IFNB1
GeneProduct
281845 (Entrez Gene)
IFNG
GeneProduct
281237 (Entrez Gene)
IL10
GeneProduct
281246 (Entrez Gene)
IL11
GeneProduct
IL12
GeneProduct
IL12B
GeneProduct
281857 (Entrez Gene)
IL13
GeneProduct
281247 (Entrez Gene)
IL15
GeneProduct
281248 (Entrez Gene)
IL1A
GeneProduct
281250 (Entrez Gene)
IL1B
GeneProduct
281251 (Entrez Gene)
IL2
GeneProduct
280822 (Entrez Gene)
IL3
GeneProduct
280823 (Entrez Gene)
IL4
GeneProduct
280824 (Entrez Gene)
IL5
GeneProduct
280825 (Entrez Gene)
IL6
GeneProduct
280826 (Entrez Gene)
IL7
GeneProduct
280827 (Entrez Gene)
PDGFA
GeneProduct
505908 (Entrez Gene)
TGFB1
GeneProduct
282089 (Entrez Gene)
TNF
GeneProduct
280943 (Entrez Gene)
TRA
GeneProduct
TRB
GeneProduct
Annotated Interactions
No annotated interactions
Views
Pathway
Discussion
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions