Regulation of actin cytoskeleton (Pan troglodytes)

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RTKLamellipodiaFocal adhesionassemblyActomyosinassembly contractionChemotactic factorGPCRstress fiberActin polymerization-pPI3KChemotatic factorGFGPCRRASStabilizationof actinRASGrowth Factor (GF)Focal adhesion pathwayActin polymerizationstress fiberMAPK Signalingpathway+pFocal adhesion pathwayRTKAdherens junction pathwayFilipodiaActin polymerizationPI3KFocal complexassembly?Gene ExpressionPDGFRBPIP4K2CMAPK4ACTBARHGEF6BCAR1RHOXF2FGFR2PIP5KL1ABI2ACTG1PIP4K2AAcetylcholineFGF9FGF14PDGFBRASSF7FGF6ENAHFGF11PIP5K1BCSKGIT1VCLPIK3R1PAK7FGF2ACTBPIP4K2ABAIAP2MYL3GNG12BDKRB1PDGFAPIK3C2GPIP4K2BGRLF1FGF13FGF16ROCK1FGF3FGF7CFL1RHOXF2SSH1APCMYL1CD14PIK3CGARHGEF4PPP1R12AITGA1NRASF2RARHGEF1RHOAWASF1CHRM1MOSLPSBRAFPAK1FGF23PAK2RHOXF2MSNCHRM4BradykininPIK3CARAF1MRASApc2DOCK1FGF4BDKRB2KRASACTG1PIP5K1APIP2CHRM3CHRM2NCKAP1RAC1WASF2FGF8RHOXF2TMSB4XPIK3R2FGF21PDGFRAFN1FGF18MAP2K1FGF17ARPC5PAK3ACTBSOS1RDXROCK2LIMK1RAC3FGF22F2CDC42SOS2PIK3R5FGF12PIK3R3RRAS2SSH3PIK3C2APIK3C3MYLKFGFR3FGD1RRASMAPK6FGF20MAPK3EGFRCYFIP2ARHGEF6RAC1P4BAIAP2PIP3PIK3CBIQGAP1VIL1RHOXF2GNA13WASPAK4GNA12LOC442775ACTG1EGFMAP2K2PAK6RAC2PIP5K1CRHOXF2VCLSLC9A1CHRM5PIP2MAPK1VIL2FGF10CFL2PTK2GSNFGFR1ACTN1PIK3R4VAV1FGF5FGFR4PFN1MYH10FGF1PXNPik3c2bPIK3CDCRKSSH2ARHGEF7PFN1ARPC5


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
GenMAPP remarks 
Adapted from KEGG (right-click to see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r20783) with a 74% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
128551view04:35, 12 February 2024EweitzModified title
114262view13:59, 2 January 2021EgonwThree more pathways clickable
72131view07:57, 25 October 2013Mkutmonadded datasource to pathway datanodes
71673view19:41, 17 October 2013MaintBotAutomated update of data sources
69266view18:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
48143view18:34, 9 May 2012MaintBotUpdating from human to fix xrefs
41574view02:00, 2 March 2011MaintBotRemoved redundant pathway information and comments
34302view22:05, 9 December 2009MaintBotAutomatic update of empty xrefs
33594view09:54, 1 December 2009MaintBotRemoved group label
31614view22:15, 13 August 2009MaintBotFixed text labels
30513view21:46, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI2GeneProduct459892 (Entrez Gene)
ACTBGeneProduct450133 (Entrez Gene)
ACTG1GeneProduct746570 (Entrez Gene)
ACTN1GeneProduct452993 (Entrez Gene)
APCGeneProduct461999 (Entrez Gene)
ARHGEF1GeneProduct
ARHGEF4GeneProduct470538 (Entrez Gene)
ARHGEF6GeneProduct473803 (Entrez Gene)
ARHGEF7GeneProduct452673 (Entrez Gene)
ARPC5GeneProduct457574 (Entrez Gene)
AcetylcholineMetabolite
Apc2GeneProduct
BAIAP2GeneProduct454951 (Entrez Gene)
BCAR1GeneProduct454246 (Entrez Gene)
BDKRB1GeneProduct
BDKRB2GeneProduct467547 (Entrez Gene)
BRAFGeneProduct463781 (Entrez Gene)
BradykininMetabolite
CD14GeneProduct462118 (Entrez Gene)
CDC42GeneProduct456609 (Entrez Gene)
CFL1GeneProduct745772 (Entrez Gene)
CFL2GeneProduct452853 (Entrez Gene)
CHRM1GeneProduct451272 (Entrez Gene)
CHRM2GeneProduct463758 (Entrez Gene)
CHRM3GeneProduct469725 (Entrez Gene)
CHRM4GeneProduct466504 (Entrez Gene)
CHRM5GeneProduct503515 (Entrez Gene)
CRKGeneProduct747142 (Entrez Gene)
CSKGeneProduct453745 (Entrez Gene)
CYFIP2GeneProduct462221 (Entrez Gene)
DOCK1GeneProduct739420 (Entrez Gene)
EGFGeneProduct461435 (Entrez Gene)
EGFRGeneProduct463415 (Entrez Gene)
ENAHGeneProduct
F2GeneProduct451158 (Entrez Gene)
F2RGeneProduct471510 (Entrez Gene)
FGD1GeneProduct
FGF10GeneProduct471553 (Entrez Gene)
FGF11GeneProduct748965 (Entrez Gene)
FGF12GeneProduct471041 (Entrez Gene)
FGF13GeneProduct465886 (Entrez Gene)
FGF1GeneProduct462158 (Entrez Gene)
FGF14GeneProduct739338 (Entrez Gene)
FGF16GeneProduct473676 (Entrez Gene)
FGF17GeneProduct472708 (Entrez Gene)
FGF18GeneProduct739611 (Entrez Gene)
FGF20GeneProduct739665 (Entrez Gene)
FGF21GeneProduct468948 (Entrez Gene)
FGF22GeneProduct468631 (Entrez Gene)
FGF23GeneProduct747164 (Entrez Gene)
FGF2GeneProduct641462 (Entrez Gene)
FGF3GeneProduct466693 (Entrez Gene)
FGF4GeneProduct747727 (Entrez Gene)
FGF5GeneProduct471190 (Entrez Gene)
FGF6GeneProduct747181 (Entrez Gene)
FGF7GeneProduct744975 (Entrez Gene)
FGF8GeneProduct745174 (Entrez Gene)
FGF9GeneProduct744731 (Entrez Gene)
FGFR1GeneProduct464122 (Entrez Gene)
FGFR2GeneProduct466220 (Entrez Gene)
FGFR3GeneProduct461067 (Entrez Gene)
FGFR4GeneProduct462301 (Entrez Gene)
FN1GeneProduct459926 (Entrez Gene)
GIT1GeneProduct454549 (Entrez Gene)
GNA12GeneProduct463234 (Entrez Gene)
GNA13GeneProduct454827 (Entrez Gene)
GNG12GeneProduct
GRLF1GeneProduct
GSNGeneProduct464706 (Entrez Gene)
IQGAP1GeneProduct467762 (Entrez Gene)
ITGA1GeneProduct461880 (Entrez Gene)
KRASGeneProduct473387 (Entrez Gene)
LIMK1GeneProduct463466 (Entrez Gene)
LOC442775GeneProduct
LPSMetaboliteC00338 (Kegg Compound)
MAP2K1GeneProduct450188 (Entrez Gene)
MAP2K2GeneProduct456390 (Entrez Gene)
MAPK1GeneProduct458680 (Entrez Gene)
MAPK3GeneProduct454037 (Entrez Gene)
MAPK4GeneProduct
MAPK6GeneProduct453439 (Entrez Gene)
MOSGeneProduct472772 (Entrez Gene)
MRASGeneProduct
MSNGeneProduct747081 (Entrez Gene)
MYH10GeneProduct455090 (Entrez Gene)
MYL1GeneProduct459915 (Entrez Gene)
MYL3GeneProduct
MYLKGeneProduct460640 (Entrez Gene)
NCKAP1GeneProduct459801 (Entrez Gene)
NRASGeneProduct742713 (Entrez Gene)
PAK1GeneProduct451439 (Entrez Gene)
PAK2GeneProduct460965 (Entrez Gene)
PAK3GeneProduct450118 (Entrez Gene)
PAK4GeneProduct
PAK6GeneProduct
PAK7GeneProduct469876 (Entrez Gene)
PDGFAGeneProduct
PDGFBGeneProduct458844 (Entrez Gene)
PDGFRAGeneProduct461318 (Entrez Gene)
PDGFRBGeneProduct462188 (Entrez Gene)
PFN1GeneProduct
PIK3C2AGeneProduct451052 (Entrez Gene)
PIK3C2GGeneProduct465321 (Entrez Gene)
PIK3C3GeneProduct455385 (Entrez Gene)
PIK3CAGeneProduct460858 (Entrez Gene)
PIK3CBGeneProduct471079 (Entrez Gene)
PIK3CDGeneProduct457922 (Entrez Gene)
PIK3CGGeneProduct463649 (Entrez Gene)
PIK3R1GeneProduct461836 (Entrez Gene)
PIK3R2GeneProduct455855 (Entrez Gene)
PIK3R3GeneProduct456565 (Entrez Gene)
PIK3R4GeneProduct460692 (Entrez Gene)
PIK3R5GeneProduct455085 (Entrez Gene)
PIP2MetaboliteC04637 (Kegg Compound)
PIP3MetaboliteC05981 (Kegg Compound)
PIP4K2AGeneProduct742458 (Entrez Gene)
PIP4K2BGeneProduct746830 (Entrez Gene)
PIP4K2CGeneProduct467044 (Entrez Gene)
PIP5K1AGeneProduct457288 (Entrez Gene)
PIP5K1BGeneProduct464513 (Entrez Gene)
PIP5K1CGeneProduct455590 (Entrez Gene)
PIP5KL1GeneProduct464758 (Entrez Gene)
PPP1R12AGeneProduct452095 (Entrez Gene)
PTK2GeneProduct464422 (Entrez Gene)
PXNGeneProduct452303 (Entrez Gene)
Pik3c2bGeneProduct457657 (Entrez Gene)
RAC1GeneProduct
RAC1P4GeneProduct
RAC2GeneProduct742575 (Entrez Gene)
RAC3GeneProduct
RAF1GeneProduct460182 (Entrez Gene)
RASSF7GeneProduct466303 (Entrez Gene)
RDXGeneProduct466776 (Entrez Gene)
RHOAGeneProduct461014 (Entrez Gene)
RHOXF2GeneProduct473763 (Entrez Gene)
ROCK1GeneProduct455326 (Entrez Gene)
ROCK2GeneProduct470307 (Entrez Gene)
RRAS2GeneProduct451038 (Entrez Gene)
RRASGeneProduct468955 (Entrez Gene)
SLC9A1GeneProduct456669 (Entrez Gene)
SOS1GeneProduct459171 (Entrez Gene)
SOS2GeneProduct452897 (Entrez Gene)
SSH1GeneProduct467124 (Entrez Gene)
SSH2GeneProduct454551 (Entrez Gene)
SSH3GeneProduct
TMSB4XGeneProduct
VAV1GeneProduct455647 (Entrez Gene)
VCLGeneProduct450531 (Entrez Gene)
VIL1GeneProduct470646 (Entrez Gene)
VIL2GeneProduct
WASGeneProduct
WASF1GeneProduct462935 (Entrez Gene)
WASF2GeneProduct456675 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP944"
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