Wnt signaling pathway (Pan troglodytes)
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Ubiquitin Tagged
B - Catenin
-Catenin
Cytoskeleton
P
26S Proteasome Degredation
B
Nucleus
Recruitment to Unknown
Phosphorylated
Ubiquitin Conjugating Enzyme
Apoptosis
Frizzled Ligands
Transcriptional Activation
FZD5
PRKD1
CTNNB1
WNT7A
FRAT1
FZD6
WNT10A
PRKCQ
DVL1
PRKCA
FZD3
WNT6
JUN
CCND3
FZD9
TCF-1/LEF
FBXW2
CCND1
WNT7B
PRKCD
DVL3
WNT16
PRKCG
RAC1
SFRP4
PPP2R5E
WNT4
CSNK1E
WNT3A
WNT5B
FZD8
WNT2B
PLAU
WNT11
PRKCH
LDLR
CCND2
PRKCE
PRKCI
PRKCB1
FZD1
AXIN1
PPP2R5C
FZD7
GSK3B
FZD10
MYC
FOSL1
MAPK9
MAPK10
WNT3
APC
PRKCZ
RHOA
WNT10B
WNT16
WNT2
WNT1
FZD2
PAFAH1B1
DVL2
WNT5A
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP428(r28695)
with a 72% conversion rate.
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Nusse R; ''Wnt signaling in disease and in development.''; Cell Res, 2005
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
117412
view
10:40, 21 May 2021
Eweitz
Modified title
71688
view
19:42, 17 October 2013
MaintBot
Automated update of data sources
69291
view
18:41, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67754
view
11:59, 26 June 2013
Ddigles
Ontology Term : 'Wnt signaling pathway' added !
41601
view
02:01, 2 March 2011
MaintBot
Removed redundant pathway information and comments
35127
view
13:38, 11 February 2010
Thomas
connected line
35119
view
13:24, 11 February 2010
Thomas
added literature
35109
view
13:16, 11 February 2010
Thomas
Modified description
34330
view
22:15, 9 December 2009
MaintBot
Automatic update of empty xrefs
33559
view
09:43, 1 December 2009
MaintBot
Removed group label
31587
view
22:04, 13 August 2009
MaintBot
Fixed text labels
30468
view
21:31, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
APC
GeneProduct
461999 (Entrez Gene)
AXIN1
GeneProduct
453789 (Entrez Gene)
CCND1
GeneProduct
747688 (Entrez Gene)
CCND2
GeneProduct
747123 (Entrez Gene)
CCND3
GeneProduct
462689 (Entrez Gene)
CSNK1E
GeneProduct
458829 (Entrez Gene)
CTNNB1
GeneProduct
450183 (Entrez Gene)
DVL1
GeneProduct
457191 (Entrez Gene)
DVL2
GeneProduct
455236 (Entrez Gene)
DVL3
GeneProduct
460882 (Entrez Gene)
FBXW2
GeneProduct
464698 (Entrez Gene)
FOSL1
GeneProduct
745919 (Entrez Gene)
FRAT1
GeneProduct
466169 (Entrez Gene)
FZD10
GeneProduct
467160 (Entrez Gene)
FZD1
GeneProduct
463524 (Entrez Gene)
FZD2
GeneProduct
FZD3
GeneProduct
472726 (Entrez Gene)
FZD5
GeneProduct
470627 (Entrez Gene)
FZD6
GeneProduct
464327 (Entrez Gene)
FZD7
GeneProduct
459881 (Entrez Gene)
FZD8
GeneProduct
466040 (Entrez Gene)
FZD9
GeneProduct
472405 (Entrez Gene)
GSK3B
GeneProduct
470896 (Entrez Gene)
MOUSE:KG38 MOUSE
JUN
GeneProduct
456893 (Entrez Gene)
LDLR
GeneProduct
455722 (Entrez Gene)
MAPK10
GeneProduct
461358 (Entrez Gene)
MAPK9
GeneProduct
462336 (Entrez Gene)
MYC
GeneProduct
464393 (Entrez Gene)
PAFAH1B1
GeneProduct
454422 (Entrez Gene)
PLAU
GeneProduct
738078 (Entrez Gene)
PPP2R5C
GeneProduct
453170 (Entrez Gene)
PPP2R5E
GeneProduct
452962 (Entrez Gene)
PRKCA
GeneProduct
454832 (Entrez Gene)
PRKCB1
GeneProduct
PRKCD
GeneProduct
PRKCE
GeneProduct
PRKCG
GeneProduct
456276 (Entrez Gene)
PRKCH
GeneProduct
746068 (Entrez Gene)
PRKCI
GeneProduct
450143 (Entrez Gene)
PRKCQ
GeneProduct
450288 (Entrez Gene)
PRKCZ
GeneProduct
743533 (Entrez Gene)
PRKD1
GeneProduct
452834 (Entrez Gene)
RAC1
GeneProduct
RHOA
GeneProduct
461014 (Entrez Gene)
SFRP4
GeneProduct
463356 (Entrez Gene)
TCF-1/LEF
GeneProduct
WNT10A
GeneProduct
459952 (Entrez Gene)
WNT10B
GeneProduct
451870 (Entrez Gene)
WNT11
GeneProduct
451431 (Entrez Gene)
WNT16
GeneProduct
737375 (Entrez Gene)
WNT1
GeneProduct
742674 (Entrez Gene)
WNT2
GeneProduct
463673 (Entrez Gene)
WNT2B
GeneProduct
457103 (Entrez Gene)
WNT3
GeneProduct
468297 (Entrez Gene)
WNT3A
GeneProduct
469698 (Entrez Gene)
WNT4
GeneProduct
469212 (Entrez Gene)
WNT5A
GeneProduct
WNT5B
GeneProduct
467191 (Entrez Gene)
WNT6
GeneProduct
WNT7A
GeneProduct
WNT7B
GeneProduct
Annotated Interactions
No annotated interactions
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Discussion
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions