Biogenic amine synthesis (Canis familiaris)

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1Synthesis pathways for biogenic aminesfollow solid arrows through enzymatic steps,while degradation steps follow dashed arrows.AcetylserotoninCHATSerotoninMAOAMelatoninHistamineGAD2PhenylalanineCOMTTyrosineEpinephrineHistidineDDCHDCASMTGAD1TryptophanTPH1MAOADBHL-DOPA5-hydroxy-tryptophanNorepinephrineGlutamateCholineDDCAcetylcholineTHACHEAANATPAHPNMTDopamineGABADDC


Description

Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source: http://www.whatislife.com/reader2/Metabolism/pathway/Neurotransmitter.html

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP550(r21838) with a 50% conversion rate.

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Ontology Terms

 

Bibliography

  1. Purves, Dale, Augustine, George J., Fitzpatrick, David, Katz, Lawrence C., LaMantia, Anthony-Samuel, McNamara, James O., Williams, S. Mark.; ''Neuroscience''; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=neurosci&part=A405, 2001

History

View all...
CompareRevisionActionTimeUserComment
117439view10:51, 21 May 2021EweitzModified title
106042view11:56, 16 August 2019MaintBotHMDB identifier normalization
89462view13:13, 15 September 2016Mkutmonremove space in ontology term id
71493view19:19, 17 October 2013MaintBotAutomated update of data sources
68606view23:31, 5 July 2013MaintBotUpdated to 2013 gpml schema
67083view10:04, 26 June 2013Christine ChichesterOntology Term : 'biogenic amine biosynthetic pathway' added !
40766view21:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
35159view14:37, 11 February 2010ThomasModified description
35158view14:37, 11 February 2010Thomasadded literature
34035view18:50, 9 December 2009MaintBotAutomatic update of empty xrefs
32554view13:07, 17 August 2009MaintBotFixed text labels
32236view12:51, 15 August 2009MaintBotFixed text labels
31744view12:01, 14 August 2009MaintBotFixed group labels
31252view19:52, 13 August 2009MaintBotFixed text labels
30687view22:45, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
5-hydroxy-tryptophanMetabolite
AANATGeneProduct483331 (Entrez Gene)
ACHEGeneProduct489828 (Entrez Gene)
ASMTGeneProduct
AcetylcholineMetabolite
AcetylserotoninMetabolite
CHATGeneProduct486775 (Entrez Gene)
COMTGeneProduct445450 (Entrez Gene)
CholineMetabolite
DBHGeneProduct448806 (Entrez Gene)
DDCGeneProduct606852 (Entrez Gene)
DopamineMetabolite
EpinephrineMetaboliteHMDB00068 (HMDB)
GABAMetaboliteHMDB00112 (HMDB)
GAD1GeneProduct478794 (Entrez Gene)
GAD2GeneProduct487107 (Entrez Gene)
GlutamateMetabolite
HDCGeneProduct487551 (Entrez Gene)
HistamineMetabolite
HistidineMetabolite
L-DOPAMetabolite
MAOAGeneProduct403450 (Entrez Gene)
MelatoninMetaboliteHMDB01389 (HMDB)
NorepinephrineMetabolite
PAHGeneProduct475446 (Entrez Gene)
PNMTGeneProduct491023 (Entrez Gene)
PhenylalanineMetabolite
SerotoninMetabolite
THGeneProduct403444 (Entrez Gene)
TPH1GeneProduct
TryptophanMetabolite
TyrosineMetabolite

Annotated Interactions

No annotated interactions
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