G13 signaling pathway (Rattus norvegicus)

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1MembraneRufflingStress FiberDisappearanceActin PolymerizationFilopodia FormationContraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber Contraction13CytokinesisGActin ReorganizationCell-Cell AdhesionActin PolymerizationActivated Rho AAnti-ApoptoticDisassembly of ActinRtknRac1MybphRock1Rock2Ppp1cbPkn1Pip4k2aDiaph1Sra1RhoaLimk1IQGAP2ArhgdibMyl1CitMapk10ArhgdigPik3r2Map3k4Pak3Cfl2Tnk2WASRhpn2PIK3CAArhgef1Cfl1CDC42CALM1Pfn1Rps6kb1Pik3cbPik3cdIqgap1Gna13Sh3rf1WASL


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP524(r21780) with a 81% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
116968view10:26, 16 May 2021EweitzModified title
95754view14:07, 19 January 2018MkutmonHomology conversion update
72030view13:02, 24 October 2013Mkutmonfixed unconnected lines
69447view19:06, 8 July 2013MaintBotUpdated to 2013 gpml schema
67277view10:30, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
41775view02:42, 2 March 2011MaintBotRemoved redundant pathway information and comments
35415view10:32, 12 February 2010Thomasfixed sra1 annotation
35414view10:30, 12 February 2010Thomasremoved braces, fixed connection
35412view10:26, 12 February 2010ThomasModified description
35410view10:26, 12 February 2010Thomasadded literature
34142view19:33, 9 December 2009MaintBotAutomatic update of empty xrefs
32453view17:23, 15 August 2009MaintBotFixed text labels
32134view13:56, 14 August 2009MaintBotFixed group labels
31471view21:19, 13 August 2009MaintBotFixed text labels
31004view01:02, 30 July 2009MaintBotConverted from Homo sapiens
21772view11:32, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:G13 Signaling Pathway]] moved to [[Pathway:WP520]]: Moved to stable identifier
8068view13:46, 7 January 2008MaintBot[[Pathway:Rat:G13 Signaling Pathway]] moved to [[Pathway:Rattus norvegicus:G13 Signaling Pathway]]: Renaming species
7656view16:07, 18 December 2007MaintBotfixed category names
7231view12:41, 4 November 2007MaintBotAdded categories to GPML
19465view22:20, 22 May 2007M.Ramirezgpml file for [[Rat:G13_Signaling_Pathway]]
6543view22:20, 22 May 2007A.Chowgpml file for [[Rat:G13_Signaling_Pathway]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ArhgdibGeneProduct362456 (Entrez Gene)
ArhgdigGeneProduct360500 (Entrez Gene)
Arhgef1GeneProduct60323 (Entrez Gene)
CALM1GeneProduct24242 (Entrez Gene)
CDC42GeneProduct64465 (Entrez Gene)
Cfl1GeneProduct29271 (Entrez Gene)
Cfl2GeneProduct366624 (Entrez Gene)
CitGeneProduct83620 (Entrez Gene)
Diaph1GeneProduct307483 (Entrez Gene)
Gna13GeneProduct303634 (Entrez Gene)
IQGAP2GeneProduct
Iqgap1GeneProduct361598 (Entrez Gene)
Limk1GeneProduct65172 (Entrez Gene)
Map3k4GeneProduct308106 (Entrez Gene)
Mapk10GeneProduct25272 (Entrez Gene)
MybphGeneProduct83708 (Entrez Gene)
Myl1GeneProduct56781 (Entrez Gene)
PIK3CAGeneProduct170911 (Entrez Gene)
Pak3GeneProduct29433 (Entrez Gene)
Pfn1GeneProduct64303 (Entrez Gene)
Pik3cbGeneProduct85243 (Entrez Gene)
Pik3cdGeneProduct366508 (Entrez Gene) P42338
Pik3r2GeneProduct29741 (Entrez Gene)
Pip4k2aGeneProduct116723 (Entrez Gene)
Pkn1GeneProduct29355 (Entrez Gene)
Ppp1cbGeneProduct25594 (Entrez Gene)
Rac1GeneProduct363875 (Entrez Gene)
RhoaGeneProduct117273 (Entrez Gene)
Rhpn2GeneProduct308516 (Entrez Gene)
Rock1GeneProduct81762 (Entrez Gene) S69211
Rock2GeneProduct25537 (Entrez Gene) BAA31594
Rps6kb1GeneProduct83840 (Entrez Gene) A41687
RtknGeneProduct297383 (Entrez Gene)
Sh3rf1GeneProduct306417 (Entrez Gene) Posh
Sra1GeneProduct252891 (Entrez Gene)
Tnk2GeneProduct303882 (Entrez Gene) S33596
WASGeneProduct317371 (Entrez Gene)
WASLGeneProduct682507 (Entrez Gene)

Annotated Interactions

No annotated interactions
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