Intracellular trafficking of CFTR (Rattus norvegicus)

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Recycling PathwayvesikelActinVesikelrecycling endosomGTPsabiliesing complex desolvesbudding ofActinrecycling endosomPlasmamembran (apical)Lysosomlate endosomearly endosomEndocytic PathwayTGNActinvesikelCFTRCFTRCFTRCFTRCFTRMyosin-VICFTRNHERF1CFTRTc10CFTRCl -Rab7CFTREzrinEzrinCFTRCFTRCFTRCFTRCFTRCFTRCALCFTRRab9Myosin-VIEzrinRab7SYN6CALNHERF1CFTREzrinNHERF1CFTRCFTRNHERF1CFTRCFTRRab11aCFTRRab5aCFTRCALRab11aCFTRCftr31, 4, 652


Description

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Quality Tags

Ontology Terms

 

Bibliography

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  1. Wennerberg K, Rossman KL, Der CJ; ''The Ras superfamily at a glance.''; J Cell Sci, 2005 PubMed Europe PMC Scholia
  2. Charest A, Lane K, McMahon K, Housman DE; ''Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
  3. Cheng J, Cebotaru V, Cebotaru L, Guggino WB; ''Syntaxin 6 and CAL mediate the degradation of the cystic fibrosis transmembrane conductance regulator.''; Mol Biol Cell, 2010 PubMed Europe PMC Scholia
  4. Swiatecka-Urban A, Duhaime M, Coutermarsh B, Karlson KH, Collawn J, Milewski M, Cutting GR, Guggino WB, Langford G, Stanton BA; ''PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
  5. Picciano JA, Ameen N, Grant BD, Bradbury NA; ''Rme-1 regulates the recycling of the cystic fibrosis transmembrane conductance regulator.''; Am J Physiol Cell Physiol, 2003 PubMed Europe PMC Scholia
  6. Gentzsch M, Chang XB, Cui L, Wu Y, Ozols VV, Choudhury A, Pagano RE, Riordan JR; ''Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator.''; Mol Biol Cell, 2004 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
126275view04:26, 20 April 2023EgonwLicense is CCZero
97314view13:42, 9 May 2018Fehrhartfixed connections
82986view00:31, 17 November 2015Mkutmonadded title and authors to references
82976view23:45, 16 November 2015Mkutmonfixed outdated identifiers
79336view12:07, 21 March 2015EgonwThe "Myosin-VI" identifier is from Entrez Gene.
79335view12:04, 21 March 2015EgonwModified description
78471view10:27, 7 January 2015MaintBotadded missing graphIds
72090view21:27, 24 October 2013Mkutmonadded datasource for "CAL"
71827view19:31, 18 October 2013MaintBotUpdated UniProt/TrEMBL data source
67768view12:56, 26 June 2013DdiglesOntology Term : 'protein transport pathway' added !
58955view18:26, 21 February 2013MaintBotUpdated Ensembl data source
41706view02:37, 2 March 2011MaintBotRemoved redundant pathway information and comments
36247view01:01, 12 March 2010KhanspersModified categories
36148view14:33, 3 March 2010Tom85Modified description
36147view14:25, 3 March 2010Tom85New pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CALGeneProduct362650
CALProtein362650 (Entrez Gene)
CFTRProteinAAA73561.1 (Other)
CftrProteinENSRNOG00000008284 (Ensembl Rat)
Cl -Metabolite
EzrinProteinNP_062230.1 (Ensembl Rat)
EzrinProteinNP_062230.1 (Uniprot/TrEMBL)
Myosin-VIProtein315840 (Other)
NHERF1ProteinQ9JJ19 (Uniprot/TrEMBL)
Rab11aGeneProductENSRNOG00000011302 (Ensembl Rat)
Rab5aProteinENSRNOG00000012180 (Ensembl Rat)
Rab7GeneProductENSRNOG00000012247 (Ensembl Rat)
Rab9ProteinENSRNOG00000030443 (Ensembl Rat)
SYN6GeneProduct
Tc10GeneProduct85428 (Entrez Gene)

Annotated Interactions

No annotated interactions

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