TNF-alpha and mucus production in lung epythelium (Rattus norvegicus)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Lora JM, Zhang DM, Liao SM, Burwell T, King AM, Barker PA, Singh L, Keaveney M, Morgenstern J, Gutierrez-Ramos JC, Coyle AJ, Fraser CC; ''Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism.''; J Biol Chem, 2005 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	126276	view	04:26, 20 April 2023	Egonw	License is CCZero
	87777	view	11:07, 25 July 2016	MirellaKalafati	Ontology Term : 'signaling pathway' added !
	82987	view	00:40, 17 November 2015	Mkutmon	fixed unconnected lines
	82977	view	23:47, 16 November 2015	Mkutmon	fixed outdated identifiers
	58946	view	18:07, 21 February 2013	MaintBot	Updated Ensembl data source
	41692	view	02:36, 2 March 2011	MaintBot	Removed redundant pathway information and comments
	36248	view	01:02, 12 March 2010	Khanspers	Modified categories
	36152	view	14:54, 3 March 2010	Julia139	Modified description
	36151	view	14:51, 3 March 2010	Julia139	Modified description
	36150	view	14:49, 3 March 2010	Julia139	Periodical save, work in progress
	36149	view	14:37, 3 March 2010	Julia139	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
EGFR	GeneProduct	24329 (Entrez Gene)
ERK	GeneProduct	116590 (Entrez Gene)
Grb2	GeneProduct	81504 (Entrez Gene)
IKBa	GeneProduct	ENSRNOG00000007390 (Ensembl Rat)
IKKa	GeneProduct	309361 (Entrez Gene)
IKKb	GeneProduct	84351 (Entrez Gene)
Il6	GeneProduct	24498 (Entrez Gene)
MEK	GeneProduct	170851 (Entrez Gene)
Muc2	GeneProduct	24572 (Entrez Gene)
Muc5ac	GeneProduct	682837 (Entrez Gene)
NF-kB	GeneProduct	81736 (Entrez Gene)
Nemo	GeneProduct	309295 (Entrez Gene)
Raf	GeneProduct	24703 (Entrez Gene)
Ras	GeneProduct	PF00071 (Pfam)
Ripk2	GeneProduct	362491 (Entrez Gene)
SOS	GeneProduct	313845 (Entrez Gene)
Shc	GeneProduct	85385 (Entrez Gene)
Sp1	GeneProduct	24790 (Entrez Gene)
TNFR1	GeneProduct	25625 (Entrez Gene)
Tgfa	GeneProduct	24827 (Entrez Gene)
Tlr4	GeneProduct	29260 (Entrez Gene)
Tnfa	GeneProduct	24835 (Entrez Gene)
Tradd	GeneProduct	246756 (Entrez Gene)
Traf2	GeneProduct	311786 (Entrez Gene)
p50	GeneProduct	81736 (Entrez Gene)
p65	GeneProduct	309165 (Entrez Gene)
pp90 rsk	GeneProduct	117269 (Entrez Gene)

Annotated Interactions

No annotated interactions