HG_Playground (Homo sapiens)

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Revision as of 14:43, 10 March 2010 by Piet (Talk | contribs)
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1Cell DivisionTranslocation to nucleusApoptosisGrowth ArrestCell cycle arrestMotilityMAPK3E2F1CLUPRB1NF1MYCNCDK2PIK3CAPTNPKD1TP53CCND1AKT2PPTPRDNRASPPTENPHOX2BXRCC6IRS9EZH2FOXO3600 GenesPmirMAP3K150 GenesPIK3R1PRKCZCDKN1CDLL3ALKBCL2PTPN11NOTCH3MSX1E2F5TP53INP1BAX


Description

Reflects the current status of research in the Human Genetics Department of the AMC in Amsterdam.

This is confidential. The pathway organizes results from wet lab experiments in the IMR32 neuroblastoma cell line.

Readouts are from Affymetrix array, western blot

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Bibliography


History

CompareRevisionActionTimeUserComment
36587view11:40, 6 April 2010PietDeleted pathway: Temporary subselection
36221view14:43, 10 March 2010PietChanged title; this is a playgroundpathway
36220view14:41, 10 March 2010PietNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
50 GenesGeneProduct50 Genes regulated; to be listed here
600 GenesGeneProductList genes here
AKT2GeneProduct208 (Entrez Gene)
ALKGeneProduct427 (Entrez Gene)
BAXGeneProduct581 (Entrez Gene)
BCL2GeneProduct596 (Entrez Gene)
CCND1GeneProduct595 (Entrez Gene)
CDK2GeneProduct1017 (Entrez Gene)
CDKN1CGeneProduct1786 (Entrez Gene) 38 Genes additionally regulated
CLUGeneProduct1191 (Entrez Gene)
DLL3GeneProduct10683 (Entrez Gene)
E2F1GeneProduct1869 (Entrez Gene)
E2F5GeneProduct1875 (Entrez Gene)
EZH2GeneProduct2146 (Entrez Gene)
FOXO3GeneProduct2309 (Entrez Gene)
IRS9GeneProduct?? IRS9 not found in Entrez Gene or Protein
MAP3K1GeneProduct4214 (Entrez Gene) MEK
MAPK3GeneProduct5595 (Entrez Gene) ERK
MSX1GeneProduct4487 (Entrez Gene)
MYCNGeneProduct4613 (Entrez Gene)
NF1GeneProduct4763 (Entrez Gene)
NOTCH3GeneProduct4854 (Entrez Gene)
NRASGeneProduct4893 (Entrez Gene) And other RAS proteins?
PMetabolitePhosphorylation on residue Ser46
PHOX2BGeneProduct8929 (Entrez Gene)
PIK3CAGeneProduct5290 (Entrez Gene) Alias p110
PIK3R1GeneProduct5295 (Entrez Gene) Alias p85a
PKD1GeneProduct5310 (Entrez Gene)
PRKCZGeneProduct5590 (Entrez Gene)
PTENGeneProduct5728 (Entrez Gene)
PTNGeneProduct5764 (Entrez Gene)
PTPN11GeneProduct5781 (Entrez Gene)
PTPRDGeneProduct5789 (Entrez Gene)
RB1GeneProduct5925 (Entrez Gene)
TP53GeneProduct7157 (Entrez Gene)
TP53INP1GeneProduct94241 (Entrez Gene)
  • 38 Additional regulated genes: to be listed here
  • Type your comment here
XRCC6GeneProduct2547 (Entrez Gene)
mirRna

Annotated Interactions

No annotated interactions

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