ACE Inhibitor Pathway (Sus scrofa)

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The renin-angiotensin-aldosterone system (RAAS) is central to the control of blood pressure and the target of several types of anti-hypertensive drugs. This pathway depicts a simplified representation of the pharmacodynamics (PD) of RAAS-acting drugs including candidate genes for the pharmacogenomics (PGx) of ACE inhibitors, angiotensin receptor blockers (ARBs), renin inhibitor aliskiren and aldosterone receptor antagonists. Source: PharmGKB (http://www.pharmgkb.org/do/serve?objId=PA2023&objCls=Pathway)

GenMAPP remarks 

Adapted from PharmGKB

HomologyConvert 

This pathway was inferred from Homo sapiens pathway WP554(r34805) with a 0% conversion rate.