HG_Shared_Pathway_CorrectIds_ (Homo sapiens)

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1CENP-A/I/MNucleusMotilityMCentrosomeCPCSG1G2?MembraneApoptosisCCNB1/2AURKBRB1RASCDKN2A (p16)PMSX1TCF4NOTCH3-ICCDKN1B (p27)CDKN1C (p57)MYCNPHOX2BTACC2PBOREALINASCL1ERKHEY1FOXO3CCNA1/2PCCNG2CDK4/6SURVIVINAKTCDK1PCDK2LIN28BBMP4CDCA3 (TOME1)TP53CDKN1A (p21)PIK3R1PIK3CACCND1CDK2CCNE1/2MEKESCO2FOXR1PFOXO3Pre-RCNF1DLL3JAG1ALKNOTCH3BMPR2PPPP


Description

Reflects the current status of research in the Human Genetics Department of the AMC in Amsterdam.

This is confidential. The pathway organizes results from wet lab experiments in the IMR32 neuroblastoma cell line.

Readouts are from Affymetrix array, western blot

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Bibliography


History

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CompareRevisionActionTimeUserComment
44548view09:56, 19 September 2011PietDeleted pathway: Obsolete
38113view13:57, 12 August 2010PietAdded ids
38112view13:53, 12 August 2010PietCreated complex
38111view13:40, 12 August 2010PietMinor font change
38110view13:34, 12 August 2010PietAdded complexes
38109view13:27, 12 August 2010PietPeriodical save, work in progress
38108view13:15, 12 August 2010PietPeriodical save, work in progress
38107view13:05, 12 August 2010PietPeriodical save, work in progress
38106view12:23, 12 August 2010PietCorrecting ids
38105view12:21, 12 August 2010PietPeriodical save, work in progress
38104view12:10, 12 August 2010PietPeriodical save, work in progress
38103view12:09, 12 August 2010Pietcorrecting ids
38102view12:00, 12 August 2010PietPeriodical save, work in progress
38101view11:48, 12 August 2010PietTemp save
38100view11:40, 12 August 2010PietCorrecting ids
38099view11:30, 12 August 2010PietPeriodical save, work in progress
38098view09:43, 12 August 2010PietPeriodical save, work in progress
38097view09:40, 12 August 2010PietRemoved colors, correcting ids
38096view09:14, 12 August 2010PietPeriodical save, work in progress
38095view09:03, 12 August 2010PietPeriodical save, work in progress
38086view15:43, 11 August 2010PietChanging receptors to appr geneids
38085view15:39, 11 August 2010PietPeriodical save, work in progress
38084view15:27, 11 August 2010PietNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AKTGeneProduct208 (Entrez Gene)
ASCL1GeneProduct429 (Entrez Gene)
AURKBGeneProduct9212 (Entrez Gene)
BMP4GeneProduct652 (Entrez Gene)
BOREALINGeneProduct55143 (Entrez Gene)
CCNA1/2GeneProduct
CCNB1/2GeneProduct
CCND1GeneProduct595 (Entrez Gene)
CCNE1/2GeneProduct
CCNG2GeneProduct901 (Entrez Gene)
CDCA3 (TOME1)GeneProduct83461 (Entrez Gene)
CDK1GeneProduct983 (Entrez Gene)
CDK2GeneProduct1017 (Entrez Gene)
CDK4/6GeneProduct
CDKN1A (p21)GeneProduct1026 (Entrez Gene)
CDKN1B (p27)GeneProduct1027 (Entrez Gene)
CDKN1C (p57)GeneProduct1786 (Entrez Gene) 38 Genes additionally regulated
CDKN2A (p16)GeneProduct1029 (Entrez Gene)
ERKGeneProduct5595 (Entrez Gene) ERK
ESCO2GeneProduct157570 (Entrez Gene)
FOXO3GeneProduct2309 (Entrez Gene)
FOXR1GeneProduct283150 (Entrez Gene)
HEY1GeneProduct23462 (Entrez Gene)
LIN28BGeneProduct389421 (Entrez Gene)
MEKGeneProduct4214 (Entrez Gene) MEK
MSX1GeneProduct4487 (Entrez Gene)
MYCNGeneProduct4613 (Entrez Gene)
NF1GeneProduct4763 (Entrez Gene)
NOTCH3-ICGeneProduct4854 (Entrez Gene)
PMetabolite
PHOX2BGeneProduct8929 (Entrez Gene)
PIK3CAGeneProduct5290 (Entrez Gene) Alias p110
PIK3R1GeneProduct5295 (Entrez Gene) Alias p85a
Pre-RCGeneProduct
RASGeneProduct4893 (Entrez Gene) And other RAS proteins?
RB1GeneProduct5925 (Entrez Gene)
SURVIVINGeneProduct332 (Entrez Gene)
TACC2GeneProduct10579 (Entrez Gene)
TCF4GeneProduct6934 (Entrez Gene)
TP53GeneProduct7157 (Entrez Gene)

Annotated Interactions

No annotated interactions

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