G13 Signaling Pathway (Homo sapiens)

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1Stress FiberDisappearanceAnti-ApoptoticContraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber ContractionActin PolymerizationCytokinesisDisassembly of ActinActin PolymerizationFilopodia FormationGActivated Rho A13Membrane RufflingActin ReorganizationCell-Cell AdhesionMYL1PAK3MAP3K4WASLCDC42LIMK1ARHGDIGROCK2PIP5K2ARHOAIQGAP2CFL1p140 Sra-1PPP1CBPKN1WASRPS6KB1CITCALM1MYBPHARHGEF1GNA13DIAPH1IQGAP1PFN1MAPK10PIK3CBROCK1RHPN2PIK3CATNK2PIK3R2ARHGDIBRAC1RTKNSH3MD2PIK3CDCFL2


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

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Bibliography


History

CompareRevisionActionTimeUserComment
38181view18:24, 23 August 2010KhanspersDeleted pathway: Duplicate
38159view13:48, 19 August 2010LiangdpNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGDIBGeneProduct397 (Entrez Gene)
ARHGDIGGeneProduct398 (Entrez Gene)
ARHGEF1GeneProduct9138 (Entrez Gene)
CALM1GeneProduct801 (Entrez Gene)
CDC42GeneProduct998 (Entrez Gene)
CFL1GeneProduct1072 (Entrez Gene)
CFL2GeneProduct1073 (Entrez Gene)
CITGeneProduct11113 (Entrez Gene)
DIAPH1GeneProduct1729 (Entrez Gene)
GNA13GeneProduct10672 (Entrez Gene)
IQGAP1GeneProduct8826 (Entrez Gene)
IQGAP2GeneProduct10788 (Entrez Gene)
LIMK1GeneProduct3984 (Entrez Gene)
MAP3K4GeneProduct4216 (Entrez Gene)
MAPK10GeneProduct5602 (Entrez Gene)
MYBPHGeneProduct4608 (Entrez Gene)
MYL1GeneProduct4632 (Entrez Gene)
PAK3GeneProduct5063 (Entrez Gene)
PFN1GeneProduct5216 (Entrez Gene)
PIK3CAGeneProduct5290 (Entrez Gene)
PIK3CBGeneProduct5291 (Entrez Gene)
PIK3CDGeneProduct5293 (Entrez Gene) P42338
PIK3R2GeneProduct5296 (Entrez Gene)
PIP5K2AGeneProduct5305 (Entrez Gene)
PKN1GeneProduct5585 (Entrez Gene)
PPP1CBGeneProduct5500 (Entrez Gene)
RAC1GeneProduct5879 (Entrez Gene)
RHOAGeneProduct387 (Entrez Gene)
RHPN2GeneProduct85415 (Entrez Gene)
ROCK1GeneProduct6093 (Entrez Gene) S69211
ROCK2GeneProduct9475 (Entrez Gene) BAA31594
RPS6KB1GeneProduct6198 (Entrez Gene) A41687
RTKNGeneProduct6242 (Entrez Gene)
SH3MD2GeneProduct57630 (Entrez Gene) Posh
TNK2GeneProduct10188 (Entrez Gene) S33596
WASGeneProduct7454 (Entrez Gene)
WASLGeneProduct8976 (Entrez Gene)
p140 Sra-1GeneProduct

Annotated Interactions

No annotated interactions

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