G13 Signaling Pathway (Homo sapiens)

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1Actin ReorganizationCell-Cell AdhesionMembrane RufflingCytokinesisContraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber ContractionActivated Rho AStress FiberDisappearanceAnti-ApoptoticDisassembly of Actin13GActin PolymerizationActin PolymerizationFilopodia FormationPAK3MAP3K4RAC1CDC42LIMK1TNK2RHPN2ROCK1PFN1ARHGEF1IQGAP1CFL2WASMYBPHMAPK10WASLIQGAP2MYL1ARHGDIGPKN1GNA13PIK3R2CITDIAPH1PIP5K2APIK3CARPS6KB1RTKNSH3MD2p140 Sra-1CALM1RHOAPPP1CBARHGDIBCFL1ROCK2PIK3CBPIK3CD


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

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Bibliography


History

CompareRevisionActionTimeUserComment
38168view03:14, 22 August 2010AlexanderPicoDeleted pathway: duplicate 1597
38160view13:51, 19 August 2010LiangdpNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGDIBGeneProduct397 (Entrez Gene)
ARHGDIGGeneProduct398 (Entrez Gene)
ARHGEF1GeneProduct9138 (Entrez Gene)
CALM1GeneProduct801 (Entrez Gene)
CDC42GeneProduct998 (Entrez Gene)
CFL1GeneProduct1072 (Entrez Gene)
CFL2GeneProduct1073 (Entrez Gene)
CITGeneProduct11113 (Entrez Gene)
DIAPH1GeneProduct1729 (Entrez Gene)
GNA13GeneProduct10672 (Entrez Gene)
IQGAP1GeneProduct8826 (Entrez Gene)
IQGAP2GeneProduct10788 (Entrez Gene)
LIMK1GeneProduct3984 (Entrez Gene)
MAP3K4GeneProduct4216 (Entrez Gene)
MAPK10GeneProduct5602 (Entrez Gene)
MYBPHGeneProduct4608 (Entrez Gene)
MYL1GeneProduct4632 (Entrez Gene)
PAK3GeneProduct5063 (Entrez Gene)
PFN1GeneProduct5216 (Entrez Gene)
PIK3CAGeneProduct5290 (Entrez Gene)
PIK3CBGeneProduct5291 (Entrez Gene)
PIK3CDGeneProduct5293 (Entrez Gene) P42338
PIK3R2GeneProduct5296 (Entrez Gene)
PIP5K2AGeneProduct5305 (Entrez Gene)
PKN1GeneProduct5585 (Entrez Gene)
PPP1CBGeneProduct5500 (Entrez Gene)
RAC1GeneProduct5879 (Entrez Gene)
RHOAGeneProduct387 (Entrez Gene)
RHPN2GeneProduct85415 (Entrez Gene)
ROCK1GeneProduct6093 (Entrez Gene) S69211
ROCK2GeneProduct9475 (Entrez Gene) BAA31594
RPS6KB1GeneProduct6198 (Entrez Gene) A41687
RTKNGeneProduct6242 (Entrez Gene)
SH3MD2GeneProduct57630 (Entrez Gene) Posh
TNK2GeneProduct10188 (Entrez Gene) S33596
WASGeneProduct7454 (Entrez Gene)
WASLGeneProduct8976 (Entrez Gene)
p140 Sra-1GeneProduct

Annotated Interactions

No annotated interactions

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