Folate-alcohol and cancer pathway hypotheses (Homo sapiens)
From WikiPathways
Description
No description
Quality Tags
Ontology Terms
Bibliography
- Hwang PH, Lian L, Zavras AI; ''Alcohol intake and folate antagonism via CYP2E1 and ALDH1: effects on oral carcinogenesis.''; Med Hypotheses, 2012 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
5,10-Methylene-THF | Metabolite | HMDB01533 (HMDB) | |
5-Methyl THF | Metabolite | ||
ADH | GeneProduct | ||
ALDH1A1 | GeneProduct | 216 (Entrez Gene) | |
ALDH1L1 | GeneProduct | 10840 (Entrez Gene) | |
Acetate | Metabolite | ||
CBS | GeneProduct | 875 (Entrez Gene) | |
CYP2E1 | GeneProduct | 1571 (Entrez Gene) | |
Cystathionine | Metabolite | HMDB00099 (HMDB) | |
Cysteine | Metabolite | HMDB00574 (HMDB) | |
Ethanol | Metabolite | HMDB00108 (HMDB) | |
Folate | Metabolite | ||
Homocysteine | Metabolite | HMDB00742 (HMDB) | |
MTHFR | GeneProduct | 4524 (Entrez Gene) | |
Methionine | Metabolite | HMDB00696 (HMDB) | |
SAH | GeneProduct | ||
SAM | GeneProduct | ||
THF | GeneProduct | ||
↑ALDH1A1 | GeneProduct | 216 (Entrez Gene) | |
↑ALDH1L1 | GeneProduct | 10840 (Entrez Gene) | |
↑Acetaldehyde | Metabolite | HMDB00990 (HMDB) | |
↑C/EBPB | GeneProduct | 1051 | |
↑CREB | GeneProduct |
Annotated Interactions
No annotated interactions