Electron transport chain (Rattus norvegicus)

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MatrixComplex IVComplex IIF0 ComplexComplex IStalkF1 ComplexAssemblyComplex VATP Synthase C subunitNADH-UbiquinoneOxidoreductaseUncoupling ProteinUbiquinol-Cytochrome CReductaseIntermembraneSpaceSuccinate-UbiquinoneOxidoreductaseAdenine NucleotideTranslocatorbinds ATP Synthase betaComplex IIICytochrome COxidaseCYTBATP5ECox4i1ND5Ndufv2SdhcNdufc2COX7A2COX3ATPNdufs1Atp5dNdufb5Cox17NDUFA9Ucp3NADHATP5HH+H+SuccinateCytochrome CNdufb6Atp5c1ND4LCOX7A3O2Ndufs3ATP6Cox5aNdufb10Cox6a1Ndufc1Ndufv3Cox6c1Slc25a27COX6B1Atp5jCox15Ndufa5Ucp1Ndufb7H+Atp5oAtp5f1e-SdhbUqcrc1FADFADH2Ndufs2Uqcrc2ND1COX2COX1Cox6a2Ndufa4UqcrNdufs5Cox7a2lAtp5a1UqcrqCOX7CNdufs4H2OSco1Ndufs8LOC679739UQCRBSlc25a4H+Slc25a14NAD+Cox5bNdufa3RGD1560896Ndufa2Atpif1ATP8Atp5g1Ndufb2Ndufv1ND3Atp5be-Ndufa12ND6Atp5g3Ndufa1Ndufb9Ndufa8ND4Cox7bSlc25a5UbiquinoneAtp5iAtp5j2UCRCNdufa7NDUFB4Ndufa10l1H+Atp5le-TCA CycleNdufs7Ndufb8Cox11Ndufab1Surf1Uqcrfs1UQCRHSdhdH+Ndufb3Atp5g2SdhaUcp2NDUFB1Atp5sND2COX7A1Ndufa6H+Cox8a


Description

An electron transport chain(ETC) couples a chemical reaction between an electron donor (such as NADH) and an electron acceptor (such as O2) to the transfer of H+ ions across a membrane, through a set of mediating biochemical reactions. These H+ ions are used to produce adenosine triphosphate (ATP), the main energy intermediate in living organisms, as they move back across the membrane.

In mitochondria, it is the conversion of oxygen to water, NADH to NAD+ and succinate to fumarate that drives the transfer of H+ ions.

Source: Wikipedia (wikipedia:Electron_transport_chain)

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP111(r20917) with a 74% conversion rate.

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Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
128031view17:04, 21 January 2024EweitzRefine orthologs, remove those missing in rat; all WikiPathways content is CC0
128030view16:52, 21 January 2024EweitzAdjust label positions to mitigate occlusion
128029view16:50, 21 January 2024EweitzRefine layout, standardize case
116956view10:07, 16 May 2021EweitzModified title
113947view06:14, 11 December 2020EgonwAnother clickable pathway
109405view17:43, 16 March 2020L DupuisFixed interaction
107001view13:45, 17 September 2019MaintBotHMDB identifier normalization
95793view14:40, 19 January 2018MkutmonHomology conversion update
79221view13:42, 15 March 2015EgonwReplaced the HMDB H2 identifier with H+ from ChEBI.
71772view20:30, 17 October 2013MaintBotAutomated update of data sources
71294view16:57, 17 October 2013MaintBotAutomated update of data sources
69341view18:51, 8 July 2013MaintBotUpdated to 2013 gpml schema
68397view07:38, 5 July 2013EgonwRemoved HMDB as data source where no identifier was given.
67193view10:19, 26 June 2013Christine ChichesterOntology Term : 'electron transport chain pathway' added !
62844view05:03, 3 May 2013MaintBotUpdated UniProt data source
41653view02:34, 2 March 2011MaintBotRemoved redundant pathway information and comments
38664view14:02, 23 September 2010FerryJagersLinked TCA Cycle
35241view19:46, 11 February 2010AlexanderPicoModified description
34051view19:02, 9 December 2009MaintBotAutomatic update of empty xrefs
32473view17:31, 15 August 2009MaintBotFixed text labels
32162view14:05, 14 August 2009MaintBotFixed group labels
31481view21:24, 13 August 2009MaintBotFixed text labels
30948view00:42, 30 July 2009MaintBotConverted from Homo sapiens
20801view11:29, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Electron Transport Chain]] moved to [[Pathway:WP59]]: Moved to stable identifier
8012view13:46, 7 January 2008MaintBot[[Pathway:Rat:Electron Transport Chain]] moved to [[Pathway:Rattus norvegicus:Electron Transport Chain]]: Renaming species
7629view16:05, 18 December 2007MaintBotfixed category names
7342view12:42, 4 November 2007MaintBotAdded categories to GPML
19423view22:20, 22 May 2007M.Ramirezgpml file for [[Rat:Electron_Transport_Chain]]
6534view22:20, 22 May 2007Kdahlquistgpml file for [[Rat:Electron_Transport_Chain]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATP5EGeneProduct245958 (Entrez Gene)
ATP5HGeneProduct641434 (Entrez Gene)
ATP6GeneProduct26197 (Entrez Gene)
ATP8GeneProduct26196 (Entrez Gene)
ATPMetaboliteC00002 (Kegg Compound)
Atp5a1GeneProduct65262 (Entrez Gene)
Atp5bGeneProduct171374 (Entrez Gene)
Atp5c1GeneProduct116550 (Entrez Gene)
Atp5dGeneProduct245965 (Entrez Gene)
Atp5f1GeneProduct171375 (Entrez Gene)
Atp5g1GeneProduct29754 (Entrez Gene)
Atp5g2GeneProduct171082 (Entrez Gene)
Atp5g3GeneProduct114630 (Entrez Gene)
Atp5iGeneProduct140608 (Entrez Gene)
Atp5j2GeneProduct690441 (Entrez Gene)
Atp5jGeneProduct94271 (Entrez Gene)
Atp5lGeneProduct300677 (Entrez Gene)
Atp5oGeneProduct192241 (Entrez Gene)
Atp5sGeneProduct362749 (Entrez Gene)
Atpif1GeneProduct25392 (Entrez Gene)
COX1GeneProduct26195 (Entrez Gene)
COX2GeneProduct26198 (Entrez Gene)
COX3GeneProduct26204 (Entrez Gene)
COX6B1GeneProduct502592 (Entrez Gene)
COX7A1GeneProduct
COX7A2GeneProduct29507 (Entrez Gene)
COX7A3GeneProduct
COX7CGeneProduct100188937 (Entrez Gene)
CYTBGeneProduct26192 (Entrez Gene)
Cox11GeneProduct690300 (Entrez Gene)
Cox15GeneProduct309391 (Entrez Gene)
Cox17GeneProduct89786 (Entrez Gene)
Cox4i1GeneProduct29445 (Entrez Gene)
Cox5aGeneProduct252934 (Entrez Gene)
Cox5bGeneProduct94194 (Entrez Gene)
Cox6a1GeneProduct25282 (Entrez Gene)
Cox6a2GeneProduct25278 (Entrez Gene)
Cox6c1GeneProduct286962 (Entrez Gene)
Cox7a2lGeneProduct298762 (Entrez Gene)
Cox7bGeneProduct303393 (Entrez Gene)
Cox8aGeneProduct171335 (Entrez Gene)
Cytochrome CMetaboliteC00524 (Kegg Compound)
FADMetaboliteC00016 (Kegg Compound)
FADH2MetaboliteC01352 (Kegg Compound)
H+MetaboliteHMDB01362 (HMDB)
H2OMetaboliteHMDB02111 (HMDB)
LOC679739GeneProduct679739 (Entrez Gene)
NAD+MetaboliteC00003 (Kegg Compound)
NADHMetaboliteC00004 (Kegg Compound)
ND1GeneProduct26193 (Entrez Gene)
ND2GeneProduct26194 (Entrez Gene)
ND3GeneProduct26199 (Entrez Gene)
ND4GeneProduct26201 (Entrez Gene)
ND4LGeneProduct26200 (Entrez Gene)
ND5GeneProduct26202 (Entrez Gene)
ND6GeneProduct26203 (Entrez Gene)
NDUFA9GeneProduct362440 (Entrez Gene)
NDUFB1GeneProduct
NDUFB4GeneProduct288088 (Entrez Gene)
Ndufa10l1GeneProduct316632 (Entrez Gene)
Ndufa12GeneProduct299739 (Entrez Gene)
Ndufa1GeneProduct363441 (Entrez Gene)
Ndufa2GeneProduct291660 (Entrez Gene)
Ndufa3GeneProduct691001 (Entrez Gene)
Ndufa4GeneProduct681024 (Entrez Gene)
Ndufa5GeneProduct25488 (Entrez Gene)
Ndufa6GeneProduct315167 (Entrez Gene)
Ndufa7GeneProduct299643 (Entrez Gene)
Ndufa8GeneProduct296658 (Entrez Gene)
Ndufab1GeneProduct293453 (Entrez Gene)
Ndufb10GeneProduct681418 (Entrez Gene)
Ndufb2GeneProduct362344 (Entrez Gene)
Ndufb3GeneProduct301427 (Entrez Gene)
Ndufb5GeneProduct294964 (Entrez Gene)
Ndufb6GeneProduct297990 (Entrez Gene)
Ndufb7GeneProduct361385 (Entrez Gene)
Ndufb8GeneProduct293991 (Entrez Gene)
Ndufb9GeneProduct299954 (Entrez Gene)
Ndufc1GeneProduct689938 (Entrez Gene)
Ndufc2GeneProduct293130 (Entrez Gene)
Ndufs1GeneProduct301458 (Entrez Gene)
Ndufs2GeneProduct289218 (Entrez Gene)
Ndufs3GeneProduct295923 (Entrez Gene)
Ndufs4GeneProduct499529 (Entrez Gene)
Ndufs5GeneProduct362588 (Entrez Gene)
Ndufs7GeneProduct362837 (Entrez Gene)
Ndufs8GeneProduct293652 (Entrez Gene)
Ndufv1GeneProduct293655 (Entrez Gene)
Ndufv2GeneProduct81728 (Entrez Gene)
Ndufv3GeneProduct64539 (Entrez Gene)
O2MetaboliteHMDB01377 (HMDB)
RGD1560896GeneProduct498885 (Entrez Gene)
Sco1GeneProduct497930 (Entrez Gene)
SdhaGeneProduct157074 (Entrez Gene)
SdhbGeneProduct298596 (Entrez Gene)
SdhcGeneProduct289217 (Entrez Gene)
SdhdGeneProduct363061 (Entrez Gene)
Slc25a14GeneProduct85263 (Entrez Gene)
Slc25a27GeneProduct85262 (Entrez Gene)
Slc25a4GeneProduct85333 (Entrez Gene)
Slc25a5GeneProduct25176 (Entrez Gene)
SuccinateMetaboliteC00042 (Kegg Compound)
Surf1GeneProduct64463 (Entrez Gene)
TCA CyclePathway
UCRCGeneProduct
UQCRBGeneProduct362897 (Entrez Gene)
UQCRHGeneProduct366448 (Entrez Gene)
UbiquinoneMetabolite
Ucp1GeneProduct24860 (Entrez Gene)
Ucp2GeneProduct54315 (Entrez Gene)
Ucp3GeneProduct25708 (Entrez Gene)
UqcrGeneProduct690848 (Entrez Gene)
Uqcrc1GeneProduct301011 (Entrez Gene)
Uqcrc2GeneProduct293448 (Entrez Gene)
Uqcrfs1GeneProduct291103 (Entrez Gene)
UqcrqGeneProduct497902 (Entrez Gene)
e-MetaboliteC05359 (Kegg Compound)

Annotated Interactions

No annotated interactions
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