Genetic alterations of lung cancer (Rattus norvegicus)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung MC; ''HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation.''; Nat Cell Biol, 2001 PubMed Europe PMC Scholia
2. Osada H, Takahashi T; ''Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.''; Oncogene, 2002 PubMed Europe PMC Scholia
3. Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M; ''Repression of p15INK4b expression by Myc through association with Miz-1.''; Nat Cell Biol, 2001 PubMed Europe PMC Scholia
4. Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, Roussel MF; ''Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization.''; Genes Dev, 1998 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	126776	view	05:44, 22 June 2023	Egonw	Black boxes
	126775	view	05:42, 22 June 2023	Egonw	Removed the fill colors
	126774	view	05:39, 22 June 2023	Egonw	Modified description
	126413	view	20:14, 26 April 2023	Egonw	License is CCZero
	110692	view	13:49, 28 May 2020	Egonw	Added missing @Type annotation
	108361	view	14:51, 12 December 2019	Marvin M2	Connected lines
	108260	view	14:46, 3 December 2019	L Dupuis	Converted interactions in legend to graphical lines
	108109	view	10:18, 29 November 2019	Fehrhart	Ontology Term : 'lung cancer' added !
	108108	view	10:18, 29 November 2019	Fehrhart	Ontology Term : 'cancer pathway' added !
	85190	view	15:44, 23 April 2016	Egonw	Replaced a mim-conversion with Arrow.
	82984	view	00:10, 17 November 2015	Mkutmon	fixed special symbols in reference
	82983	view	00:07, 17 November 2015	Mkutmon	fixed outdatded identifiers
	81935	view	00:01, 6 September 2015	AlexanderPico	Quick edit to datanode annotation or property
	81934	view	00:00, 6 September 2015	AlexanderPico	Quick edit to datanode annotation or property
	81933	view	23:58, 5 September 2015	AlexanderPico	Quick edit to datanode annotation or property
	81932	view	23:57, 5 September 2015	AlexanderPico	Quick edit to datanode annotation or property
	81931	view	23:55, 5 September 2015	AlexanderPico	Quick edit to datanode annotation or property
	81662	view	16:09, 22 August 2015	MaintBot	Fixed weird characters in autors names.
	81285	view	10:22, 14 August 2015	Jmelius	update data nodes labels
	78466	view	10:27, 7 January 2015	MaintBot	added missing graphIds
	71839	view	19:44, 18 October 2013	MaintBot	removed data source from nodes without identifier
	70124	view	19:27, 12 July 2013	MaintBot	updated to 2013 schema
	70123	view	19:27, 12 July 2013	MaintBot	Modified title
	67281	view	10:31, 26 June 2013	Christine Chichester	Ontology Term : 'lung cancer pathway' added !
	58960	view	18:32, 21 February 2013	MaintBot	Updated Ensembl data source
	44969	view	14:01, 6 October 2011	Mkutmon	connected some lines
	42200	view	21:02, 7 March 2011	Khanspers	Modified categories
	42199	view	21:01, 7 March 2011	Khanspers	Fixed unconnected lines
	41729	view	02:39, 2 March 2011	MaintBot	Removed redundant pathway information and comments
	40393	view	14:38, 23 February 2011	Gustav	Modified description
	40392	view	14:37, 23 February 2011	Gustav
	40389	view	14:33, 23 February 2011	Gustav	Periodical save, work in progress
	40386	view	14:22, 23 February 2011	Gustav	Periodical save, work in progress
	40377	view	13:46, 23 February 2011	Gustav
	40372	view	13:42, 23 February 2011	Gustav	Modified description
	40360	view	13:22, 23 February 2011	Gustav
	40359	view	13:19, 23 February 2011	Gustav	Modified description
	40357	view	13:16, 23 February 2011	Gustav
	40356	view	13:15, 23 February 2011	Gustav	Periodical save, work in progress
	40352	view	13:04, 23 February 2011	Gustav	Periodical save, work in progress
	40348	view	12:54, 23 February 2011	Gustav	Periodical save, work in progress
	40341	view	12:34, 23 February 2011	Gustav	Periodical save, work in progress
	40336	view	12:23, 23 February 2011	Gustav	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
Akt1	GeneProduct	ENSRNOG00000028629 (Ensembl Rat)
ERK	GeneProduct
Egfr	GeneProduct	ENSRNOG00000004332 (Ensembl Rat)
Erbb2	GeneProduct	ENSRNOG00000006450 (Ensembl Rat)
MEK	GeneProduct
MYC	GeneProduct
PI3K	GeneProduct
Raf1	GeneProduct	ENSRNOG00000010153 (Ensembl Rat)
Rasl11b	GeneProduct	ENSRNOG00000002097 (Ensembl Rat)

Annotated Interactions

No annotated interactions