Genetic alterations of lung cancer (Rattus norvegicus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Name: New Pathway


Description

No description

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Quality Tags

Image:Featured.pngReview changes for Featured
Image:Curated.pngReview changes for Approved
Image:MissingXref.pngAnnotate nodes

Ontology Terms

Bibliography

  1. Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung MC; ''HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation.''; Nat Cell Biol, 2001 PubMed Europe PMC Scholia
  2. Osada H, Takahashi T; ''Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.''; Oncogene, 2002 PubMed Europe PMC Scholia
  3. Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M; ''Repression of p15INK4b expression by Myc through association with Miz-1.''; Nat Cell Biol, 2001 PubMed Europe PMC Scholia
  4. Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, Roussel MF; ''Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization.''; Genes Dev, 1998 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
126776
Featured
Approved
view05:44, 22 June 2023EgonwBlack boxes
126775view05:42, 22 June 2023EgonwRemoved the fill colors
126774view05:39, 22 June 2023EgonwModified description
126413view20:14, 26 April 2023EgonwLicense is CCZero
110692view13:49, 28 May 2020EgonwAdded missing @Type annotation
108361view14:51, 12 December 2019Marvin M2Connected lines
108260view14:46, 3 December 2019L DupuisConverted interactions in legend to graphical lines
108109view10:18, 29 November 2019FehrhartOntology Term : 'lung cancer' added !
108108view10:18, 29 November 2019FehrhartOntology Term : 'cancer pathway' added !
85190view15:44, 23 April 2016EgonwReplaced a mim-conversion with Arrow.
82984view00:10, 17 November 2015Mkutmonfixed special symbols in reference
82983view00:07, 17 November 2015Mkutmonfixed outdatded identifiers
81935view00:01, 6 September 2015AlexanderPicoQuick edit to datanode annotation or property
81934view00:00, 6 September 2015AlexanderPicoQuick edit to datanode annotation or property
81933view23:58, 5 September 2015AlexanderPicoQuick edit to datanode annotation or property
81932view23:57, 5 September 2015AlexanderPicoQuick edit to datanode annotation or property
81931view23:55, 5 September 2015AlexanderPicoQuick edit to datanode annotation or property
81662view16:09, 22 August 2015MaintBotFixed weird characters in autors names.
81285view10:22, 14 August 2015Jmeliusupdate data nodes labels
78466view10:27, 7 January 2015MaintBotadded missing graphIds
71839view19:44, 18 October 2013MaintBotremoved data source from nodes without identifier
70124view19:27, 12 July 2013MaintBotupdated to 2013 schema
70123view19:27, 12 July 2013MaintBotModified title
67281view10:31, 26 June 2013Christine ChichesterOntology Term : 'lung cancer pathway' added !
58960view18:32, 21 February 2013MaintBotUpdated Ensembl data source
44969view14:01, 6 October 2011Mkutmonconnected some lines
42200view21:02, 7 March 2011KhanspersModified categories
42199view21:01, 7 March 2011KhanspersFixed unconnected lines
41729view02:39, 2 March 2011MaintBotRemoved redundant pathway information and comments
40393view14:38, 23 February 2011GustavModified description
40392view14:37, 23 February 2011Gustav
40389view14:33, 23 February 2011GustavPeriodical save, work in progress
40386view14:22, 23 February 2011GustavPeriodical save, work in progress
40377view13:46, 23 February 2011Gustav
40372view13:42, 23 February 2011GustavModified description
40360view13:22, 23 February 2011Gustav
40359view13:19, 23 February 2011GustavModified description
40357view13:16, 23 February 2011Gustav
40356view13:15, 23 February 2011GustavPeriodical save, work in progress
40352view13:04, 23 February 2011GustavPeriodical save, work in progress
40348view12:54, 23 February 2011GustavPeriodical save, work in progress
40341view12:34, 23 February 2011GustavPeriodical save, work in progress
40336view12:23, 23 February 2011GustavNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
Akt1GeneProductENSRNOG00000028629 (Ensembl Rat)
CyclinDGeneProduct
ERKGeneProduct
EgfrGeneProductENSRNOG00000004332 (Ensembl Rat)
Erbb2GeneProductENSRNOG00000006450 (Ensembl Rat)
MEKGeneProduct
MYCGeneProduct
PI3KGeneProduct
Raf1GeneProductENSRNOG00000010153 (Ensembl Rat)
Rasl11bGeneProductENSRNOG00000002097 (Ensembl Rat)
SMAD4_RATGeneProductENSRNOG00000015634 (Ensembl Rat)
Smad2GeneProductENSRNOG00000018140 (Ensembl Rat)
TGF-beta R1/2GeneProductENSRNOG00000002418 (Ensembl Rat)
Tgfb1GeneProductENSRNOG00000020652 (Ensembl Rat)
p15INK4BGeneProduct
p16INK4AGeneProduct

Annotated Interactions

No annotated interactions

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