From WikiPathways
ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Name: New Pathway
Description
No description
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Quality Tags
Review changes for Featured Revision 126776 of this pathway was tagged to be featured on the front page of WikiPathways by Egon Willighagen .
Review changes for Approved Revision 126776 of this pathway was approved for data analysis by Egon Willighagen .
Annotate nodes Comment: 4 out of 31 DataNodes have a missing external reference. Check DataNode table at the bottom of the page.
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Ontology Terms
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Bibliography
Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung MC; ''HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation.''; Nat Cell Biol, 2001 PubMed Europe PMC Scholia Osada H, Takahashi T; ''Genetic alterations of multiple tumor suppressors and oncogenes in the carcinogenesis and progression of lung cancer.''; Oncogene, 2002 PubMed Europe PMC Scholia Staller P, Peukert K, Kiermaier A, Seoane J, Lukas J, Karsunky H, Möröy T, Bartek J, Massagué J, Hänel F, Eilers M; ''Repression of p15INK4b expression by Myc through association with Miz-1.''; Nat Cell Biol, 2001 PubMed Europe PMC Scholia Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, Roussel MF; ''Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization.''; Genes Dev, 1998 PubMed Europe PMC Scholia
History
External references
DataNodes
Name Type Database reference Comment Akt1 GeneProduct ENSRNOG00000028629 (Ensembl Rat) CyclinD GeneProduct ERK GeneProduct Egfr GeneProduct ENSRNOG00000004332 (Ensembl Rat) Erbb2 GeneProduct ENSRNOG00000006450 (Ensembl Rat) MEK GeneProduct MYC GeneProduct PI3K GeneProduct Raf1 GeneProduct ENSRNOG00000010153 (Ensembl Rat) Rasl11b GeneProduct ENSRNOG00000002097 (Ensembl Rat) SMAD4_RAT GeneProduct ENSRNOG00000015634 (Ensembl Rat) Smad2 GeneProduct ENSRNOG00000018140 (Ensembl Rat) TGF-beta R1/2 GeneProduct ENSRNOG00000002418 (Ensembl Rat) Tgfb1 GeneProduct ENSRNOG00000020652 (Ensembl Rat) p15INK4B GeneProduct p16INK4A GeneProduct
Annotated Interactions
No annotated interactions