EBV LMP1 signaling (Anopheles gambiae)

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1, 4S36-PPUUPPUTES2S32-PTES1PS36-PPS32-PIKK-alphaCCL20TRADDIKK-gammaTRAF1TNFI-Kappa-BAgaP_AGAP006958TAB1TUBEREL2REL1REL1I-Kappa-BJNKIKK-betaREL2MAP3K3LMP1IKK-alphaIFNBSFC complexIL8REL1REL2REL1TRAF6MAP3K7p38REL1CCL5REL2NIKREL2REL1REL22, 3


Description

based on science-slides...

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP262(r29609) with a 52% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Song YJ, Jen KY, Soni V, Kieff E, Cahir-McFarland E; ''IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation.''; Proc Natl Acad Sci U S A, 2006 PubMed Europe PMC Scholia
  2. Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, Ninomiya-Tsuji J; ''TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.''; J Biol Chem, 2006 PubMed Europe PMC Scholia
  3. Battaglia F, Delfino S, Merello E, Puppo M, Piva R, Varesio L, Bosco MC; ''Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB.''; J Leukoc Biol, 2008 PubMed Europe PMC Scholia
  4. Lee JS, Lee JY, Son JW, Oh JH, Shin DM, Yuk JM, Song CH, Paik TH, Jo EK; ''Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis.''; Scand J Immunol, 2008 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
134198view18:30, 16 July 2024EgonwRemoved template comments
67169view10:15, 26 June 2013Christine ChichesterOntology Term : 'Epstein-Barr virus infection pathway' added !
63233view23:20, 8 May 2013AnweshaOpened to convert to GPML 2013
58805view22:59, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40471view18:47, 1 March 2011MaintBotRemoved redundant pathway information and comments
31831view12:26, 14 August 2009MaintBotFixed group labels
30793view23:40, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AgaP_AGAP006958GeneProduct1270128 (Entrez Gene)
CCL20GeneProduct
CCL5GeneProduct
I-Kappa-BGeneProduct
IFNBGeneProduct
IKK-alphaGeneProduct
IKK-alphaGeneProductAGAP009166 (Ensembl Mosquito_Ag )
IKK-betaGeneProductAGAP009166 (Ensembl Mosquito_Ag )
IKK-gammaGeneProductAGAP005933 (Ensembl Mosquito_Ag )
IL8GeneProduct
JNKGeneProduct
LMP1GeneProduct
MAP3K3GeneProduct
MAP3K7GeneProduct
NIKGeneProduct
REL1GeneProductAGAP009515 (Ensembl Mosquito_Ag )
REL2GeneProductAGAP006747 (Ensembl Mosquito_Ag )
SFC complexGeneProduct
TAB1GeneProduct
TNFGeneProduct
TRADDGeneProduct
TRAF1GeneProduct
TRAF6GeneProductAGAP003004 (Ensembl Mosquito_Ag )
TUBEGeneProductAGAP003062 (Ensembl Mosquito_Ag )
p38GeneProductAGAP009207 (Ensembl Mosquito_Ag )

Annotated Interactions

No annotated interactions
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