Complement and coagulation cascades (Bos taurus)
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C4b/2a
C3
Convertase
fibrin degredation
products
Kinin kallikrein system
Extrinsic pathway
C5a
Degredation
Cell adhesion,
migration,
profileration, etc
Classical Pathway
membrane attack complex
Muscle contraction,
Chemotaxis,
Phagocyte recruitment
Inflammation, etc.
C3b
Cell adhesion,
migration,
profileration, etc
C4a
Cross-linked
fibrin polymer
Lectin Pathway
Alternative Pathway
Zymosan,
insulin, etc.
Mediators
C3b/Bb
C3b/4b, C3b, C3d
Collagen,
basement membrane,
activated platelets, etc.
Cell lysis
Fibrinolytic system
C3a
Thrombin
Clot
Vascular injury
Complement Cascade
Antibody/antigen
complex
Platelet, monocyte,
lymphocyte,
endothelial cells,
smooth muscle cells
activation, etc
Coagulation Cascade
C9
F12
109821
KNG1
F3
THBD
F5
C2
C5AR1
MBL1
SERPIND1
VWF
MASP2
SERPINA1
PLG
FGB
C4BP
LOC616002
cd21
SERPINC1
PLAU
F13B
CD59A
CFH
PLAT
F2R
F9
Fibrin monomer
F10
Hc
C3
PROS1
SERPINF2
F8
PLAUR
H2-BF
PROC
F7
C3AR1
CRRY
CPB2
C7
F2
C6
SERPING1
C1S
CFI
BDKRB1
A2M
Daf2
C1R
C1QC
MASP1
Daf1
TFPI
C1QA
C1QB
C4
Bradykinin
SERPINE1
CR1
SERPINA5
KLKB1
ADN
C8G
Description
No description
Comments
GenMAPP notes
http://www.genome.jp/dbget-bin/get
pathway?org name=mmu&mapno=04610
GenMAPP remarks
Adapted from KEGG (see notes)
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP558(r22582)
with a 61% conversion rate.
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Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
No bibliography
History
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Compare
Revision
Action
Time
User
Comment
117491
view
11:02, 21 May 2021
Eweitz
Modified title
95800
view
14:46, 19 January 2018
Mkutmon
Homology conversion update
80847
view
15:28, 30 June 2015
Mkutmon
homology conversion
79847
view
07:34, 19 April 2015
Egonw
Replaced "Ensemble Cow" with "Ensembl".
79148
view
06:14, 5 March 2015
Khanspers
Updated conversion from Hs
71400
view
19:00, 17 October 2013
MaintBot
Automated update of data sources
63325
view
21:07, 9 May 2013
MaintBot
Updated to 2013 gpml schema
40506
view
19:28, 1 March 2011
MaintBot
Removed redundant pathway information and comments
38704
view
19:27, 23 September 2010
AlexanderPico
33749
view
23:58, 8 December 2009
MaintBot
Automatic update of empty xrefs
32517
view
12:54, 17 August 2009
MaintBot
Fixed text labels
32203
view
12:39, 15 August 2009
MaintBot
Fixed text labels
31688
view
11:46, 14 August 2009
MaintBot
Fixed group labels
31215
view
19:38, 13 August 2009
MaintBot
Fixed text labels
30625
view
22:24, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
A2M
GeneProduct
513856 (Entrez Gene)
ADN
GeneProduct
BDKRB1
GeneProduct
532119 (Entrez Gene)
Bradykinin
Metabolite
C1QA
GeneProduct
534961 (Entrez Gene)
C1QB
GeneProduct
617435 (Entrez Gene)
C1QC
GeneProduct
509968 (Entrez Gene)
C1R
GeneProduct
511581 (Entrez Gene)
C1S
GeneProduct
767827 (Entrez Gene)
C2
GeneProduct
515440 (Entrez Gene)
C3
GeneProduct
280677 (Entrez Gene)
C3AR1
GeneProduct
540702 (Entrez Gene)
C4
GeneProduct
C4BP
GeneProduct
C5AR1
GeneProduct
493645 (Entrez Gene)
C6
GeneProduct
507749 (Entrez Gene)
C7
GeneProduct
507339 (Entrez Gene)
MGI:88235 LL:109828
C8G
GeneProduct
517356 (Entrez Gene)
C9
GeneProduct
526766 (Entrez Gene)
CD59A
GeneProduct
CFH
GeneProduct
280816 (Entrez Gene)
CFI
GeneProduct
513197 (Entrez Gene)
CPB2
GeneProduct
508222 (Entrez Gene)
CR1
GeneProduct
CRRY
GeneProduct
Daf1
GeneProduct
Daf2
GeneProduct
F10
GeneProduct
790178 (Entrez Gene)
F12
GeneProduct
785029 (Entrez Gene)
F13B
GeneProduct
511483 (Entrez Gene)
F2
GeneProduct
280685 (Entrez Gene)
F2R
GeneProduct
526585 (Entrez Gene)
F3
GeneProduct
784008 (Entrez Gene)
F5
GeneProduct
280687 (Entrez Gene)
F7
GeneProduct
617960 (Entrez Gene)
F8
GeneProduct
100271720 (Entrez Gene)
F9
GeneProduct
280688 (Entrez Gene)
FGB
GeneProduct
510522 (Entrez Gene)
Fibrin monomer
Metabolite
H2-BF
GeneProduct
Hc
GeneProduct
KLKB1
GeneProduct
533547 (Entrez Gene)
KNG1
GeneProduct
280833 (Entrez Gene)
LOC616002
GeneProduct
616002 (Entrez Gene)
MASP1
GeneProduct
522347 (Entrez Gene)
MASP2
GeneProduct
505819 (Entrez Gene)
MBL1
GeneProduct
PLAT
GeneProduct
281407 (Entrez Gene)
PLAU
GeneProduct
281408 (Entrez Gene)
PLAUR
GeneProduct
281983 (Entrez Gene)
PLG
GeneProduct
280897 (Entrez Gene)
PROC
GeneProduct
281428 (Entrez Gene)
PROS1
GeneProduct
282006 (Entrez Gene)
SERPINA1
GeneProduct
280699 (Entrez Gene)
SERPINA5
GeneProduct
338050 (Entrez Gene)
SERPINC1
GeneProduct
540261 (Entrez Gene)
SERPIND1
GeneProduct
100125764 (Entrez Gene)
SERPINE1
GeneProduct
281375 (Entrez Gene)
SERPINF2
GeneProduct
282522 (Entrez Gene)
SERPING1
GeneProduct
281035 (Entrez Gene)
TFPI
GeneProduct
508763 (Entrez Gene)
THBD
GeneProduct
281529 (Entrez Gene)
VWF
GeneProduct
280958 (Entrez Gene)
cd21
GeneProduct
407126 (Entrez Gene)
109821
GeneProduct
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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