Complement and coagulation cascades (Bos taurus)

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Antibody/antigencomplexCell lysisClotFibrinolytic systemCoagulation CascadeMuscle contraction,Chemotaxis,Phagocyte recruitmentInflammation, etc.Extrinsic pathwayDegredationMediatorsC4b/2aC3ConvertaseKinin kallikrein systemC3aVascular injuryCell adhesion,migration,profileration, etcComplement CascadeZymosan,insulin, etc.C3b/BbC3b/4b, C3b, C3dClassical PathwayC4aCell adhesion,migration,profileration, etcmembrane attack complexCollagen,basement membrane,activated platelets, etc.C5aLectin PathwayThrombinfibrin degredationproductsAlternative PathwayC3bCross-linkedfibrin polymerPlatelet, monocyte,lymphocyte,endothelial cells,smooth muscle cellsactivation, etcC6PLGF8KLKB1CFHPLAUF10Daf1C3AR1MASP2FGB109821CFIA2MPLAURF2SERPING1CD59AC5AR1F2RPLATTFPIMASP1ADNPROS1F13BBradykininF7C8GVWFC3C4PROCKNG1F9SERPINE1CR1SERPINA1F3C4BPLOC616002SERPIND1BDKRB1F5HcMBL1C1RCRRYSERPINF2SERPINA5C1SC1QCC1QAC9Daf2CPB2C1QBC2Fibrin monomerTHBDcd21SERPINC1F12H2-BFC7


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/dbget-bin/get pathway?org name=mmu&mapno=04610
GenMAPP remarks 
Adapted from KEGG (see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP558(r22582) with a 61% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
134194view18:23, 16 July 2024EgonwRemoved template comments
117491view11:02, 21 May 2021EweitzModified title
95800view14:46, 19 January 2018MkutmonHomology conversion update
80847view15:28, 30 June 2015Mkutmonhomology conversion
79847view07:34, 19 April 2015EgonwReplaced "Ensemble Cow" with "Ensembl".
79148view06:14, 5 March 2015KhanspersUpdated conversion from Hs
71400view19:00, 17 October 2013MaintBotAutomated update of data sources
63325view21:07, 9 May 2013MaintBotUpdated to 2013 gpml schema
40506view19:28, 1 March 2011MaintBotRemoved redundant pathway information and comments
38704view19:27, 23 September 2010AlexanderPico
33749view23:58, 8 December 2009MaintBotAutomatic update of empty xrefs
32517view12:54, 17 August 2009MaintBotFixed text labels
32203view12:39, 15 August 2009MaintBotFixed text labels
31688view11:46, 14 August 2009MaintBotFixed group labels
31215view19:38, 13 August 2009MaintBotFixed text labels
30625view22:24, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A2MGeneProduct513856 (Entrez Gene)
ADNGeneProduct
BDKRB1GeneProduct532119 (Entrez Gene)
BradykininMetabolite
C1QAGeneProduct534961 (Entrez Gene)
C1QBGeneProduct617435 (Entrez Gene)
C1QCGeneProduct509968 (Entrez Gene)
C1RGeneProduct511581 (Entrez Gene)
C1SGeneProduct767827 (Entrez Gene)
C2GeneProduct515440 (Entrez Gene)
C3GeneProduct280677 (Entrez Gene)
C3AR1GeneProduct540702 (Entrez Gene)
C4GeneProduct
C4BPGeneProduct
C5AR1GeneProduct493645 (Entrez Gene)
C6GeneProduct507749 (Entrez Gene)
C7GeneProduct507339 (Entrez Gene) MGI:88235 LL:109828
C8GGeneProduct517356 (Entrez Gene)
C9GeneProduct526766 (Entrez Gene)
CD59AGeneProduct
CFHGeneProduct280816 (Entrez Gene)
CFIGeneProduct513197 (Entrez Gene)
CPB2GeneProduct508222 (Entrez Gene)
CR1GeneProduct
CRRYGeneProduct
Daf1GeneProduct
Daf2GeneProduct
F10GeneProduct790178 (Entrez Gene)
F12GeneProduct785029 (Entrez Gene)
F13BGeneProduct511483 (Entrez Gene)
F2GeneProduct280685 (Entrez Gene)
F2RGeneProduct526585 (Entrez Gene)
F3GeneProduct784008 (Entrez Gene)
F5GeneProduct280687 (Entrez Gene)
F7GeneProduct617960 (Entrez Gene)
F8GeneProduct100271720 (Entrez Gene)
F9GeneProduct280688 (Entrez Gene)
FGBGeneProduct510522 (Entrez Gene)
Fibrin monomerMetabolite
H2-BFGeneProduct
HcGeneProduct
KLKB1GeneProduct533547 (Entrez Gene)
KNG1GeneProduct280833 (Entrez Gene)
LOC616002GeneProduct616002 (Entrez Gene)
MASP1GeneProduct522347 (Entrez Gene)
MASP2GeneProduct505819 (Entrez Gene)
MBL1GeneProduct
PLATGeneProduct281407 (Entrez Gene)
PLAUGeneProduct281408 (Entrez Gene)
PLAURGeneProduct281983 (Entrez Gene)
PLGGeneProduct280897 (Entrez Gene)
PROCGeneProduct281428 (Entrez Gene)
PROS1GeneProduct282006 (Entrez Gene)
SERPINA1GeneProduct280699 (Entrez Gene)
SERPINA5GeneProduct338050 (Entrez Gene)
SERPINC1GeneProduct540261 (Entrez Gene)
SERPIND1GeneProduct100125764 (Entrez Gene)
SERPINE1GeneProduct281375 (Entrez Gene)
SERPINF2GeneProduct282522 (Entrez Gene)
SERPING1GeneProduct281035 (Entrez Gene)
TFPIGeneProduct508763 (Entrez Gene)
THBDGeneProduct281529 (Entrez Gene)
VWFGeneProduct280958 (Entrez Gene)
cd21GeneProduct407126 (Entrez Gene)
109821GeneProduct

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1056"
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