Tryptophan metabolism (Canis familiaris)
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Indole-3-acetate
5-(3'-Carboxy-3'-oxopropenyl)-4,6-dihydroxypicolin
C00332
Indole-3-acetaldehyde
2-Formamino
benzoylacetate
Indolepyruvate
3-(2-Aminoethyl)
-1H-indol-5-ol
Anthranilate
2,3-Dihydroxyindole
3-Hydroxyanthranilate
Formyl-5-hydroxykynurenamine
8-Methoxykynurenate
3-Indoleglycolaldehyde
Benzoate degradation via hydroxylation
Indolelactate
3-Methoxyanthranilate
C00877
Glucobrassicin
5-Hydroxy-N-formylkynurenine
Indole-3-ethanol
Isophenoxazine
5-(2'-Carboxyethyl)-4,6-dihydroxypicolinate
2-Oxoadipate
2-Aminomuconate
Melatonin
4,6-Dihydroxyquinoline
Oxaloacetate
(Z)-5-Oxohex-2-enedioate
C00527
7,8-Dihydro-7,8-dihydroxykynurenate
2-Formylaminobenzaldehyde
Nicotinate and nicotinamide metabolism
Formyl-N-acetyl-5-
methoxykynurenamine
4-(2-Aminophenyl)-2,4-dioxobutanoate
Kynurenate
3-Hydroxy-
L-kynurenine
4-(2-Amino-3-hydroxyphenyl)
-2,4-dioxobutanoate
Cinnavalininate
N-Acetylindoxyl
3-Hydroxykynurenamine
2-Aminomuconate
5-Hydroxyindoleacetaldehyde
5-Hydroxy
-L-tryptophan
Indole-3-acetaldoxime
N-Methyltryptamine
2-Oxoglutarate
Glycolysis / Gluconeogenesis
6-Hydroxykynurenate
3-Methyldioxyindole
7,8-Dihydroxykynurenate
5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate
4,8-Dihydroxyquinoline
4-(2-Amino-5-hydroxyphenyl)
-2,4-dioxobutanoate
Quinolinate
5-(2'-Formylethyl)-4,6-dihydroxypicolinate
2-Amino-3-carboxymuconate
3-Methylindolepyruvate
5-Methoxyindoleacetate
5-Hydroxyindoleacetate
5-Hydroxyindolepyruvate
L-Tryptophanyl-tRNA
Anthranilate
Formylanthranilate
5-Hydroxyindoleacetylglycine
PhenylAla, Tyr and Trp biosynthesis
Xanthurenic
N-Methylserotonin
Benzoate degradation via hydroxylation
5-Hydroxykynurenamine
C01144
6-Hydroxyindolelactate
2.1.1.47
ASMT
ALDH1A1
CYP1A1
KYNU
LOC610195
ALDH2
ABP1
ALDH2
1.14.16.-
RHOXF2
L-Kynurenine
DDC
4.2.1.84
UBR5
RHOXF2
CYP1A2
2.6.1.27
1.2.1.-
GCDH
OGDH
LOC612477
ALDH1A2
RHOXF2
PRMT1
AFMID
1.13.11.17
IDO1
3.5.1.4
CYP2C18
Indole
ALDH1A1
2.6.1.27
CYP1B1
LOC486973
MAOB
1.1.1.191
AADAT
ALDH1A2
CYP3A4
ASMT
Tryptamine
IDO1
RNF25
MAOB
INMT
UBE3A
CYP2A13
1.2.3.7
HSD17B10
4.1.1.43
HADH
1.7.3.2
ALDH9A1
Acetyl-CoA
1.13.11.23
1.14.16.3
3.5.99.5
ALDH9A1
3.2.1.147
N-Acetylisatin
1.13.11.-
1.10.3.4
CYP4F12
2.1.1.49
L-Tryptophan
DDC
MAOB
4.1.99.1
ALDH3A2
MDM2
CYP2E1
3.5.1.49
MDM2
RHOXF2
ALDH3A2
3.5.1.9
PRMT1
1.14.13.9
1.3.1.18
WARS
5-Hydroxykynurenine
AOX1
RNF25
AADAT
TDO2
N-Acetylserotonin
ACMSD
1.4.3.2
AANAT
KYNU
1.13.99.3
4.1.1.-
RHOXF2
Formylkynurenine
1.14.99.2
1.13.11.10
TPH1
DDC
DHCR24
1.1.1.110
2-Aminophenol
6-Hydroxymelatonin
IDO1
1.13.12.3
CYP19
GCDH
ECHS1
1.5.1.-
HAAO
3-Indoleacetonitrile
KYNU
MAOB
UBE3A
RHOXF2
Indole-3-acetamide
3.5.5.1
ACAT1
5-Methoxytryptamine
PRMT1
RHOXF2
RHOXF2
2.6.1.27
1.1.1.190
1.2.1.32
CAT
MDM2
Description
No description
Comments
GenMAPP notes
Converted from rat to human using ortholog information. Link to original KEGG map:
http://www.genome.ad.jp/dbget-bin/show
pathway?rno00380
GenMAPP remarks
Edited by Sebastien Burel
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP465(r30270)
with a 51% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
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Bibliography
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History
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Revision
Action
Time
User
Comment
122665
view
05:37, 28 April 2022
Egonw
Made a pathway clickable
106044
view
11:56, 16 August 2019
MaintBot
HMDB identifier normalization
104909
view
19:18, 24 June 2019
Khanspers
Modified description
104908
view
19:18, 24 June 2019
Khanspers
removed genmapp comments
104822
view
12:57, 19 June 2019
Fehrhart
Modified description
85637
view
15:35, 4 June 2016
Egonw
Replaced a Wikipedia ID with a ChEBI ID.
71451
view
19:16, 17 October 2013
MaintBot
Automated update of data sources
68501
view
21:45, 5 July 2013
MaintBot
Updated to 2013 gpml schema
48151
view
18:46, 9 May 2012
MaintBot
Updating from human to fix xrefs
40652
view
21:48, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33945
view
18:18, 9 December 2009
MaintBot
Automatic update of empty xrefs
32559
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13:08, 17 August 2009
MaintBot
Fixed text labels
32240
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12:52, 15 August 2009
MaintBot
Fixed text labels
31750
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12:03, 14 August 2009
MaintBot
Fixed group labels
31257
view
19:53, 13 August 2009
MaintBot
Fixed text labels
30695
view
22:47, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
1.1.1.110
GeneProduct
1.1.1.190
GeneProduct
1.1.1.191
GeneProduct
1.10.3.4
GeneProduct
1.13.11.-
GeneProduct
1.13.11.10
GeneProduct
1.13.11.17
GeneProduct
1.13.11.23
GeneProduct
1.13.12.3
GeneProduct
1.13.99.3
GeneProduct
1.14.13.9
GeneProduct
1.14.16.-
GeneProduct
1.14.16.3
GeneProduct
1.14.99.2
GeneProduct
1.2.1.-
GeneProduct
1.2.1.32
GeneProduct
1.2.3.7
GeneProduct
1.3.1.18
GeneProduct
1.4.3.2
GeneProduct
1.5.1.-
GeneProduct
1.7.3.2
GeneProduct
2-Aminophenol
Metabolite
2-Aminophenol
2.1.1.47
GeneProduct
2.1.1.49
GeneProduct
2.6.1.27
GeneProduct
3-Indoleacetonitrile
Metabolite
3-Indoleacetonitrile
3.2.1.147
GeneProduct
3.5.1.4
GeneProduct
3.5.1.49
GeneProduct
3.5.1.9
GeneProduct
3.5.5.1
GeneProduct
3.5.99.5
GeneProduct
4.1.1.-
GeneProduct
4.1.1.43
GeneProduct
4.1.99.1
GeneProduct
4.2.1.84
GeneProduct
5-Hydroxykynurenine
Metabolite
5-Methoxytryptamine
Metabolite
6-Hydroxymelatonin
Metabolite
AADAT
GeneProduct
486059 (Entrez Gene)
AANAT
GeneProduct
483331 (Entrez Gene)
ABP1
GeneProduct
475536 (Entrez Gene)
ACAT1
GeneProduct
489421 (Entrez Gene)
ACMSD
GeneProduct
476125 (Entrez Gene)
AFMID
GeneProduct
609011 (Entrez Gene)
ALDH1A1
GeneProduct
476323 (Entrez Gene)
ALDH1A2
GeneProduct
478319 (Entrez Gene)
ALDH2
GeneProduct
610941 (Entrez Gene)
ALDH3A2
GeneProduct
479518 (Entrez Gene)
ALDH9A1
GeneProduct
AOX1
GeneProduct
ASMT
GeneProduct
Acetyl-CoA
Metabolite
Acetyl-CoA
CAT
GeneProduct
403474 (Entrez Gene)
CYP19
GeneProduct
494003 (Entrez Gene)
CYP1A1
GeneProduct
487648 (Entrez Gene)
CYP1A2
GeneProduct
494010 (Entrez Gene)
CYP1B1
GeneProduct
483038 (Entrez Gene)
CYP2A13
GeneProduct
484494 (Entrez Gene)
CYP2C18
GeneProduct
CYP2E1
GeneProduct
415128 (Entrez Gene)
CYP3A4
GeneProduct
CYP4F12
GeneProduct
DDC
GeneProduct
606852 (Entrez Gene)
DHCR24
GeneProduct
489573 (Entrez Gene)
predicted
ECHS1
GeneProduct
480828 (Entrez Gene)
Formylkynurenine
Metabolite
Formylkynurenine
GCDH
GeneProduct
476696 (Entrez Gene)
predicted
HAAO
GeneProduct
611728 (Entrez Gene)
HADH
GeneProduct
478506 (Entrez Gene)
HSD17B10
GeneProduct
480930 (Entrez Gene)
IDO1
GeneProduct
475574 (Entrez Gene)
INMT
GeneProduct
489397 (Entrez Gene)
Indole-3-acetamide
Metabolite
Indole-3-acetamide
Indole
Metabolite
KYNU
GeneProduct
483907 (Entrez Gene)
L-Kynurenine
Metabolite
L-Kynurenine
L-Tryptophan
Metabolite
LOC486973
GeneProduct
486973 (Entrez Gene)
LOC610195
GeneProduct
610195 (Entrez Gene)
LOC612477
GeneProduct
612477 (Entrez Gene)
MAOB
GeneProduct
403451 (Entrez Gene)
MDM2
GeneProduct
403693 (Entrez Gene)
N-Acetylisatin
Metabolite
N-Acetylisatin
N-Acetylserotonin
Metabolite
N-Acetylserotonin
OGDH
GeneProduct
475499 (Entrez Gene)
PRMT1
GeneProduct
476411 (Entrez Gene)
RHOXF2
GeneProduct
611154 (Entrez Gene)
RNF25
GeneProduct
478912 (Entrez Gene)
TDO2
GeneProduct
475476 (Entrez Gene)
TPH1
GeneProduct
Tryptamine
Metabolite
UBE3A
GeneProduct
479010 (Entrez Gene)
UBR5
GeneProduct
475055 (Entrez Gene)
WARS
GeneProduct
480435 (Entrez Gene)
Annotated Interactions
No annotated interactions
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No annotated interactions