EBV LMP1 signaling (Danio rerio)

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1, 4PUTES1PS36-PPPS32-PS32-PS36-PTES2UPUrelarelap50I-Kappa-Bmap3k3map3k7map3k7CCL20chukLOC100002946irak1SFC complexrelachuktraf6JNKhsp90a.2I-Kappa-BPDLIM7ikbkgtraddp100p50TNFp50mapk1ikbkbIFNBrelarelatraf1relaCCL5p50/p52p52NIK2, 3


Description

based on science-slides...

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP262(r29609) with a 58% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, Ninomiya-Tsuji J; ''TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.''; J Biol Chem, 2006 PubMed Europe PMC Scholia
  2. Lee JS, Lee JY, Son JW, Oh JH, Shin DM, Yuk JM, Song CH, Paik TH, Jo EK; ''Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis.''; Scand J Immunol, 2008 PubMed Europe PMC Scholia
  3. Battaglia F, Delfino S, Merello E, Puppo M, Piva R, Varesio L, Bosco MC; ''Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB.''; J Leukoc Biol, 2008 PubMed Europe PMC Scholia
  4. Song YJ, Jen KY, Soni V, Kieff E, Cahir-McFarland E; ''IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation.''; Proc Natl Acad Sci U S A, 2006 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
87909view12:58, 25 July 2016SusanOntology Term : 'signaling pathway' added !
68652view05:07, 6 July 2013MaintBotUpdated to 2013 gpml schema
58789view22:45, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40821view22:17, 1 March 2011MaintBotRemoved redundant pathway information and comments
31919view12:52, 14 August 2009MaintBotFixed group labels
31038view01:17, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CCL20GeneProduct
CCL5GeneProduct
I-Kappa-BGeneProduct
IFNBGeneProduct
JNKGeneProduct
LOC100002946GeneProductENSDARG00000056824 (Ensembl Zebrafish)
NIKGeneProduct
PDLIM7GeneProductENSDARG00000030638 (Ensembl Zebrafish)
SFC complexGeneProduct
TNFGeneProduct
chukGeneProduct393287 (Entrez Gene)
chukGeneProductENSDARG00000011662 (Ensembl Zebrafish)
hsp90a.2GeneProduct565155 (Entrez Gene)
ikbkbGeneProductENSDARG00000079123 (Ensembl Zebrafish)
ikbkgGeneProductENSDARG00000017037 (Ensembl Zebrafish)
irak1GeneProductENSDARG00000025949 (Ensembl Zebrafish)
map3k3GeneProductENSDARG00000060348 (Ensembl Zebrafish)
map3k7GeneProductENSDARG00000020469 (Ensembl Zebrafish)
mapk1GeneProductENSDARG00000027552 (Ensembl Zebrafish)
p100GeneProduct
p50GeneProduct
p50/p52GeneProduct
p52GeneProduct
relaGeneProductENSDARG00000021907 (Ensembl Zebrafish)
traddGeneProductENSDARG00000036057 (Ensembl Zebrafish)
traf1GeneProductENSDARG00000069482 (Ensembl Zebrafish)
traf6GeneProductENSDARG00000028058 (Ensembl Zebrafish)

Annotated Interactions

No annotated interactions
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