Insulin signaling (Gallus gallus)

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1Insulin Receptor SubstratesTranslation RegulationTranscriptional Regulators & Immediate Early GenesMEK/MAP Kinasesp70 S6 KinasesVesicular TraffickingPI 3-KinaseMetabolic RegulationModulators of Insulin Actionp90 Rsk KinasesGlucose TransportTor SignalingRas-MAPK SignalingPDK/Akt SignalingPRKCDTBC1D4PIK3R4RPS6KA4SOCS1MAPK10MAP4K4PRKCBIRS1SHC1RCJMB04_34i9FRAP1EIF4ERPS6KA1AKT1EIF4EBP1MAPK11KIF5BIRS2SNX26RPS6KB2MAP3K2MAP4K5STXBP3STXBP4CBLGRB10GSK3BPTPRFRHOQMAP3K4GYS2PRKAA1CAP1EHD2ARF6MAPK13MAP3K10RCJMB04_36h7PIK3R2MAPK8RPS6KA3PIK3CDPPP1R3AMAPK12MAP4K3SGK2IKBKBJUNXBP1IRS4PDPK1SNAP25SGK1PRKAA2SRFCRKSOS2MAPK9SOS1PIK3C2GSTXBP2TSC1RAF1STXBP1MAPK3GRB14GRB2FOXO1ACBLBSLC2A4MAP2K7SLC2A1MAP3K5MYO1CRRADPRKCHMAP3K8SHC3MAPK1MAP3K6MAPK4FOSRAC1MAP4K2PIK3CBMAPK8CBLCLIPEMAPK14RCJMB04_4j14ENPP1RCJMB04_8f10MAP2K1EGR1KIF3APFKLTSC2VAMP2PIK3C3RCJMB04_5a10MAP3K14GYG1ELK1PTPN1PIK3R3FOXO3MAP2K4PRKCZMAP3K11SH2B2MAP3K1SNAP23RPS6KA2MAP2K6PIK3CARCJMB04_5i17MAP3K7GAB1RPS6KA5RAC2MAP3K12TRIB3AKT2MAP2K2GYS1PTENSORBS1SGK3PSCD3TPTERAPGEF1INSRPIK3C2AINPP4AARF1STX4APIK3R1PFKMMINK1HRASGSK3AMAP3K13INPPL1MAP4K1RCJMB04_16p24PTPN11RHEBMAP3K9FLOT1MAP3K3PRKCQSHC2RHOJRAB4AIGF1REHD1MAPK7SOCS3RPS6KA6PIK3CG


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP481(r28132) with a 72% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Quon MJ, Campfield LA; ''A mathematical model and computer simulation study of insulin sensitive glucose transporter regulation.''; J Theor Biol, 1991 PubMed Europe PMC Scholia
  2. Bevan P; ''Insulin signalling.''; J Cell Sci, 2001 PubMed Europe PMC Scholia
  3. Saltiel AR, Kahn CR; ''Insulin signalling and the regulation of glucose and lipid metabolism.''; Nature, 2001 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
116788view09:57, 14 May 2021EweitzModified title
95775view14:28, 19 January 2018MkutmonHomology conversion update
74226view15:18, 8 April 2014EgonwRemoved a data source where no ID was given.
68843view17:19, 8 July 2013MaintBotUpdated to 2013 gpml schema
67396view10:55, 26 June 2013DdiglesOntology Term : 'insulin signaling pathway' added !
47787view16:22, 6 April 2012Khanspersupdated xref
40981view22:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
33905view18:01, 9 December 2009MaintBotAutomatic update of empty xrefs
33433view14:55, 30 November 2009MaintBotRemoved group label
31487view21:28, 13 August 2009MaintBotFixed text labels
30312view20:40, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct395928 (Entrez Gene)
AKT2GeneProduct373973 (Entrez Gene)
ARF1GeneProduct420398 (Entrez Gene)
ARF6GeneProduct428927 (Entrez Gene)
CAP1GeneProduct419680 (Entrez Gene)
CBLGeneProduct374038 (Entrez Gene)
CBLBGeneProduct418406 (Entrez Gene)
CBLCGeneProduct
CRKGeneProduct417553 (Entrez Gene)
EGR1GeneProduct373931 (Entrez Gene)
EHD1GeneProduct
EHD2GeneProduct
EIF4EGeneProduct422703 (Entrez Gene)
EIF4EBP1GeneProduct426773 (Entrez Gene)
ELK1GeneProduct
ENPP1GeneProduct426929 (Entrez Gene)
FLOT1GeneProduct
FOSGeneProduct396512 (Entrez Gene)
FOXO1AGeneProduct374231 (Entrez Gene)
FOXO3GeneProduct421769 (Entrez Gene)
FRAP1GeneProduct419455 (Entrez Gene)
GAB1GeneProduct422456 (Entrez Gene)
GRB10GeneProduct420948 (Entrez Gene)
GRB14GeneProduct424183 (Entrez Gene)
GRB2GeneProduct386572 (Entrez Gene)
GSK3AGeneProduct
GSK3BGeneProduct418335 (Entrez Gene)
GYG1GeneProduct425050 (Entrez Gene)
GYS1GeneProduct378934 (Entrez Gene)
GYS2GeneProduct418201 (Entrez Gene)
HRASGeneProduct396229 (Entrez Gene)
IGF1RGeneProduct395889 (Entrez Gene)
IKBKBGeneProduct426792 (Entrez Gene)
INPP4AGeneProduct418690 (Entrez Gene)
INPPL1GeneProduct428692 (Entrez Gene)
INSRGeneProduct420133 (Entrez Gene)
IRS1GeneProduct429126 (Entrez Gene)
IRS2GeneProduct428017 (Entrez Gene)
IRS4GeneProduct
JUNGeneProduct424673 (Entrez Gene)
KIF3AGeneProduct416332 (Entrez Gene)
KIF5BGeneProduct420472 (Entrez Gene)
LIPEGeneProduct
MAP2K1GeneProduct415549 (Entrez Gene)
MAP2K2GeneProduct396349 (Entrez Gene)
MAP2K4GeneProduct417312 (Entrez Gene)
MAP2K6GeneProduct
MAP2K7GeneProduct
MAP3K10GeneProduct
MAP3K11GeneProduct
MAP3K12GeneProduct
MAP3K13GeneProduct424876 (Entrez Gene)
MAP3K1GeneProduct427144 (Entrez Gene)
MAP3K14GeneProduct419964 (Entrez Gene)
MAP3K2GeneProduct424225 (Entrez Gene)
MAP3K3GeneProduct419954 (Entrez Gene)
MAP3K4GeneProduct421579 (Entrez Gene)
MAP3K5GeneProduct421688 (Entrez Gene)
MAP3K6GeneProduct
MAP3K7GeneProduct421808 (Entrez Gene)
MAP3K8GeneProduct420479 (Entrez Gene)
MAP3K9GeneProduct776822 (Entrez Gene)
MAP4K1GeneProduct
MAP4K2GeneProduct
MAP4K3GeneProduct425965 (Entrez Gene)
MAP4K4GeneProduct418714 (Entrez Gene)
MAP4K5GeneProduct423576 (Entrez Gene)
MAPK10GeneProduct422592 (Entrez Gene)
MAPK11GeneProduct417739 (Entrez Gene)
MAPK12GeneProduct769763 (Entrez Gene)
MAPK1GeneProduct373953 (Entrez Gene)
MAPK13GeneProduct771145 (Entrez Gene)
MAPK14GeneProduct421183 (Entrez Gene)
MAPK3GeneProduct
MAPK4GeneProduct
MAPK7GeneProduct
MAPK8GeneProduct423778 (Entrez Gene)
MAPK9GeneProduct395983 (Entrez Gene)
MINK1GeneProduct
MYO1CGeneProduct417555 (Entrez Gene)
PDPK1GeneProduct416588 (Entrez Gene)
PFKLGeneProduct769850 (Entrez Gene)
PFKMGeneProduct374064 (Entrez Gene)
PIK3C2AGeneProduct423070 (Entrez Gene)
PIK3C2GGeneProduct418181 (Entrez Gene)
PIK3C3GeneProduct
PIK3CAGeneProduct424971 (Entrez Gene)
PIK3CBGeneProduct424826 (Entrez Gene)
PIK3CDGeneProduct419444 (Entrez Gene)
PIK3CGGeneProduct417706 (Entrez Gene)
PIK3R1GeneProduct427171 (Entrez Gene)
PIK3R2GeneProduct771142 (Entrez Gene)
PIK3R3GeneProduct429096 (Entrez Gene)
PIK3R4GeneProduct428449 (Entrez Gene)
PPP1R3AGeneProduct427858 (Entrez Gene)
PRKAA1GeneProduct427185 (Entrez Gene)
PRKAA2GeneProduct429110 (Entrez Gene)
PRKCBGeneProduct416567 (Entrez Gene)
PRKCDGeneProduct415905 (Entrez Gene)
PRKCHGeneProduct423518 (Entrez Gene)
PRKCQGeneProduct
PRKCZGeneProduct419399 (Entrez Gene)
PSCD3GeneProduct416626 (Entrez Gene)
PTENGeneProduct423675 (Entrez Gene)
PTPN11GeneProduct395815 (Entrez Gene)
PTPN1GeneProduct395688 (Entrez Gene)
PTPRFGeneProduct424568 (Entrez Gene)
RAB4AGeneProduct421532 (Entrez Gene)
RAC1GeneProduct395871 (Entrez Gene)
RAC2GeneProduct418044 (Entrez Gene)
RAF1GeneProduct396245 (Entrez Gene)
RAPGEF1GeneProduct417173 (Entrez Gene)
RCJMB04_16p24GeneProduct424991 (Entrez Gene)
RCJMB04_34i9GeneProduct417579 (Entrez Gene)
RCJMB04_36h7GeneProduct415557 (Entrez Gene)
RCJMB04_4j14GeneProduct417637 (Entrez Gene)
RCJMB04_5a10GeneProduct417430 (Entrez Gene)
RCJMB04_5i17GeneProduct415419 (Entrez Gene)
RCJMB04_8f10GeneProduct416496 (Entrez Gene)
RHEBGeneProduct420434 (Entrez Gene)
RHOJGeneProduct423513 (Entrez Gene)
RHOQGeneProduct395114 (Entrez Gene)
RPS6KA1GeneProduct386579 (Entrez Gene)
RPS6KA2GeneProduct421570 (Entrez Gene)
RPS6KA3GeneProduct418605 (Entrez Gene)
RPS6KA4GeneProduct
RPS6KA5GeneProduct423408 (Entrez Gene)
RPS6KA6GeneProduct422273 (Entrez Gene)
RPS6KB2GeneProduct
RRADGeneProduct415790 (Entrez Gene)
SGK1GeneProduct395133 (Entrez Gene)
SGK2GeneProduct419166 (Entrez Gene)
SGK3GeneProduct420167 (Entrez Gene)
SH2B2GeneProduct771172 (Entrez Gene)
SHC1GeneProduct395934 (Entrez Gene)
SHC2GeneProduct770341 (Entrez Gene)
SHC3GeneProduct431265 (Entrez Gene)
SLC2A1GeneProduct396130 (Entrez Gene)
SLC2A4GeneProduct
SNAP23GeneProduct423235 (Entrez Gene)
SNAP25GeneProduct396444 (Entrez Gene)
SNX26GeneProduct
SOCS1GeneProduct416630 (Entrez Gene)
SOCS3GeneProduct395299 (Entrez Gene)
SORBS1GeneProduct423749 (Entrez Gene)
SOS1GeneProduct425964 (Entrez Gene)
SOS2GeneProduct423572 (Entrez Gene)
SRFGeneProduct396103 (Entrez Gene)
STX4AGeneProduct
STXBP1GeneProduct404293 (Entrez Gene)
STXBP2GeneProduct
STXBP3GeneProduct424341 (Entrez Gene)
STXBP4GeneProduct417393 (Entrez Gene)
TBC1D4GeneProduct428062 (Entrez Gene)
TPTEGeneProduct418885 (Entrez Gene)
TRIB3GeneProduct
TSC1GeneProduct417166 (Entrez Gene)
TSC2GeneProduct416552 (Entrez Gene)
VAMP2GeneProduct424827 (Entrez Gene)
XBP1GeneProduct416918 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP743"
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