Complement and Coagulation Cascades (Gallus gallus)

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C4b/2aC3Convertasefibrin degredationproductsKinin kallikrein systemExtrinsic pathwayC5aDegredationCell adhesion,migration,profileration, etcClassical Pathwaymembrane attack complexMuscle contraction,Chemotaxis,Phagocyte recruitmentInflammation, etc.C3bCell adhesion,migration,profileration, etcC4aCross-linkedfibrin polymerLectin PathwayAlternative PathwayZymosan,insulin, etc.MediatorsC3b/BbC3b/4b, C3b, C3dCollagen,basement membrane,activated platelets, etc.Cell lysisFibrinolytic systemC3aThrombinClotVascular injuryComplement CascadeAntibody/antigencomplexPlatelet, monocyte,lymphocyte,endothelial cells,smooth muscle cellsactivation, etcCoagulation CascadeC9F12109821KNG1F3THBDF5C2C5AR1MBL1SERPIND1VWFMASP2SERPINA1PLGFGBC4BPMCPCR2SERPINC1PLAUF13BCD59ACFHPLATF2RF9Fibrin monomerF10HcC3PROS1SERPINF2F8PLAURH2-BFPROCF7C3AR1CRRYCPB2C7F2C6SERPING1C1SCFIBDKRB1A2MDaf2C1RC1QCMASP1Daf1TFPIC1QAC1QBC4BradykininSERPINE1CR1SERPINA5KLKB1ADNC8G


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/dbget-bin/get pathway?org name=mmu&mapno=04610
GenMAPP remarks 
Adapted from KEGG (see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP558(r22582) with a 58% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
122619view08:30, 22 April 2022DdiglesReverted to version '03:59, 23 August 2016' by Ddigles
122584view10:00, 18 April 2022EweitzModified title
89198view03:59, 23 August 2016AriuttaOntology Term : 'hemostasis pathway' added !
89197view03:59, 23 August 2016AriuttaOntology Term : 'coagulation cascade pathway' added !
89196view03:59, 23 August 2016AriuttaOntology Term : 'complement system pathway' added !
74335view13:15, 13 April 2014EgonwAdded a missing metabolite identifier.
68852view17:20, 8 July 2013MaintBotUpdated to 2013 gpml schema
40990view22:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
38705view19:28, 23 September 2010AlexanderPico
33912view18:04, 9 December 2009MaintBotAutomatic update of empty xrefs
33491view15:11, 30 November 2009MaintBotRemoved group label
31540view21:48, 13 August 2009MaintBotFixed text labels
30389view21:05, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A2MGeneProduct418251 (Entrez Gene)
ADNGeneProduct
BDKRB1GeneProduct772372 (Entrez Gene)
BradykininMetabolite
C1QAGeneProduct419504 (Entrez Gene)
C1QBGeneProduct428197 (Entrez Gene)
C1QCGeneProduct419503 (Entrez Gene)
C1RGeneProduct418295 (Entrez Gene)
C1SGeneProduct418294 (Entrez Gene)
C2GeneProduct419574 (Entrez Gene)
C3GeneProduct396370 (Entrez Gene)
C3AR1GeneProduct418198 (Entrez Gene)
C4GeneProduct426611 (Entrez Gene)
C4BPGeneProduct
C5AR1GeneProduct430484 (Entrez Gene)
C6GeneProduct431585 (Entrez Gene)
C7GeneProduct427187 (Entrez Gene) MGI:88235 LL:109828
C8GGeneProduct770691 (Entrez Gene)
C9GeneProduct
CD59AGeneProduct
CFHGeneProduct429057 (Entrez Gene)
CFIGeneProduct428773 (Entrez Gene)
CPB2GeneProduct418851 (Entrez Gene)
CR1GeneProduct
CR2GeneProduct
CRRYGeneProduct
Daf1GeneProduct
Daf2GeneProduct
F10GeneProduct395876 (Entrez Gene)
F12GeneProduct
F13BGeneProduct424355 (Entrez Gene)
F2GeneProduct395306 (Entrez Gene)
F2RGeneProduct427212 (Entrez Gene)
F3GeneProduct429084 (Entrez Gene)
F5GeneProduct374052 (Entrez Gene)
F7GeneProduct395086 (Entrez Gene)
F8GeneProduct422199 (Entrez Gene)
F9GeneProduct374258 (Entrez Gene)
FGBGeneProduct373926 (Entrez Gene)
Fibrin monomerMetabolite
H2-BFGeneProduct
HcGeneProduct
KLKB1GeneProduct
KNG1GeneProduct424957 (Entrez Gene)
MASP1GeneProduct407088 (Entrez Gene)
MASP2GeneProduct407089 (Entrez Gene)
MBL1GeneProduct
MCPGeneProduct
PLATGeneProduct426791 (Entrez Gene)
PLAUGeneProduct396424 (Entrez Gene)
PLAURGeneProduct
PLGGeneProduct421580 (Entrez Gene)
PROCGeneProduct395085 (Entrez Gene)
PROS1GeneProduct418430 (Entrez Gene)
SERPINA1GeneProduct423434 (Entrez Gene)
SERPINA5GeneProduct423435 (Entrez Gene)
SERPINC1GeneProduct424440 (Entrez Gene)
SERPIND1GeneProduct395877 (Entrez Gene)
SERPINE1GeneProduct
SERPINF2GeneProduct417561 (Entrez Gene)
SERPING1GeneProduct423132 (Entrez Gene)
TFPIGeneProduct423989 (Entrez Gene)
THBDGeneProduct428546 (Entrez Gene)
VWFGeneProduct419031 (Entrez Gene)
109821GeneProduct

Annotated Interactions

No annotated interactions
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