Oxidative stress response (Pan troglodytes)

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TF activationImmediate-earlygene inductionStress-regulated MAP kinaseInduction ofantioxidant genesInhibition of oxidasesRepression of ROS-producing systemsActivationTF inhibitionReactive Oxygen SpeciesAdaptive responseRepressionUGT1A6SOD2MGST1JUNBLOC468068SOD1MAPK10NFKB1TXN2SP1FOSCATMAPK14MAOAGPX3GSRXDHTXNRD2SOD3NQO1HMOX1GCLCMT1XGPX1LOC453744GSTT2NFIXNrf2TXNRD1


Description

No description

Comments

GenMAPP notes 
Adapted from Biochem J 1999 Sep 15;342 Pt 3:481-96 Morel Y, Barouki R. Repression of gene expression by oxidative stress. Biochem J 1999 Sep 15;342 Pt 3:481-96
GenMAPP remarks 
Adapted from rat by GenMAPP.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP408(r21540) with a 79% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
117037view14:11, 16 May 2021EweitzModified title
88285view14:42, 1 August 2016FehrhartOntology Term : 'oxidative stress response pathway' added !
71669view19:40, 17 October 2013MaintBotAutomated update of data sources
69251view18:36, 8 July 2013MaintBotUpdated to 2013 gpml schema
41558view01:59, 2 March 2011MaintBotRemoved redundant pathway information and comments
34289view22:01, 9 December 2009MaintBotAutomatic update of empty xrefs
33584view09:50, 1 December 2009MaintBotRemoved group label
31607view22:12, 13 August 2009MaintBotFixed text labels
30501view21:42, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CATGeneProduct451116 (Entrez Gene)
FOSGeneProduct453047 (Entrez Gene)
GCLCGeneProduct742732 (Entrez Gene)
GPX1GeneProduct461015 (Entrez Gene)
GPX3GeneProduct471703 (Entrez Gene)
GSRGeneProduct464099 (Entrez Gene)
GSTT2GeneProduct458962 (Entrez Gene)
HMOX1GeneProduct470195 (Entrez Gene)
JUNBGeneProduct468739 (Entrez Gene)
LOC453744GeneProduct453744 (Entrez Gene)
LOC468068GeneProduct468068 (Entrez Gene) Probe set ID: u18729
MAOAGeneProduct740491 (Entrez Gene)
MAPK10GeneProduct461358 (Entrez Gene)
MAPK14GeneProduct450161 (Entrez Gene)
MGST1GeneProduct473380 (Entrez Gene)
MT1XGeneProduct736020 (Entrez Gene)
NFIXGeneProduct
NFKB1GeneProduct461406 (Entrez Gene)
NQO1GeneProduct468012 (Entrez Gene)
Nrf2GeneProduct
SOD1GeneProduct449637 (Entrez Gene)
SOD2GeneProduct449634 (Entrez Gene)
SOD3GeneProduct461143 (Entrez Gene)
SP1GeneProduct451939 (Entrez Gene)
TXN2GeneProduct
TXNRD1GeneProduct467112 (Entrez Gene)
TXNRD2GeneProduct458654 (Entrez Gene)
UGT1A6GeneProduct739942 (Entrez Gene)
XDHGeneProduct470347 (Entrez Gene)

Annotated Interactions

No annotated interactions
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