IL-4 signaling pathway (Pan troglodytes)

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Molecule in the pathwayCY -> PMDNUExtracellularDesumoylationCY -> PMMethylationInhibitionCY -> PMCytoplasmDemethylationCY -> PMECPlasma membraneGOPalmitoylationReaction through unknown mechanisms/moleculesDDEndoplasmic reticulumDLigandUbiquitinationAccession Number: NetPath 16AutophosphorylationEndosomeDeubiquitinationAcetylationDActivationDephosphorylationMolecular associationPhosphorylationENProteins in a complex interactionTranslocationControlCY -> NUProteolytic cleavageMitochondrionERMTDSumoylationGolgi apparatusDPMCY -> NURecruitmentCYEnzyme complexDNucleus(Protein-protein interaction)ReceptorDeacetylationDGlycosylationPRKCDIRS1NFKB1PRKCIJAK2AKT1NFKB1SPI1PIK3R1PTPN6ATF2IL2RGPIK3R2IL4JAK2RASA1MAPK3STAT6MAPK1SRCPRKCIMAPK14PRKD3TYK2PTPN11PRKCZPIK3CDJAK1MAPK11IL4NCF1PTK2IL13RA1SOCS5SOCS1FYNMAPK14ADRBK2Gene SymbolPIK3CADOK2STAMIL4RBCL2L1EP300STAT6BADPRKCZPLCG1STAT1ETS1LCKSOCS3SOS1INPP5DCBLJAK3STAT5ACREBBPHMGA1HIST2H3CJAK1IL4RSTAT6RPS6KB1ELK1STAT6FESSHC1IRS2CXCR4GRB2PRKD3STAT6RELAPRKCDPAWR


Description

No description

Comments

GenMAPP notes 
NetPath 16 - IL-4 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP395(r28126) with a 74% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
117990view11:23, 23 May 2021EweitzModified title
86932view13:05, 15 July 2016MkutmonOntology Term : 'interleukin-4 signaling pathway' added !
69300view18:42, 8 July 2013MaintBotUpdated to 2013 gpml schema
41610view02:02, 2 March 2011MaintBotRemoved redundant pathway information and comments
34339view22:18, 9 December 2009MaintBotAutomatic update of empty xrefs
31609view22:13, 13 August 2009MaintBotFixed text labels
30506view21:44, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADRBK2GeneProduct
AKT1GeneProduct740898 (Entrez Gene)
ATF2GeneProduct
BADGeneProduct
BCL2L1GeneProduct458156 (Entrez Gene)
CBLGeneProduct451690 (Entrez Gene)
CREBBPGeneProduct467891 (Entrez Gene)
CXCR4GeneProduct450130 (Entrez Gene)
DOK2GeneProduct464036 (Entrez Gene)
ELK1GeneProduct
EP300GeneProduct458862 (Entrez Gene)
ETS1GeneProduct
FESGeneProduct453654 (Entrez Gene)
FYNGeneProduct462944 (Entrez Gene)
GRB2GeneProduct737245 (Entrez Gene)
Gene SymbolGeneProduct
HIST2H3CGeneProduct
HMGA1GeneProduct746594 (Entrez Gene)
IL13RA1GeneProduct735671 (Entrez Gene)
IL2RGGeneProduct465692 (Entrez Gene)
IL4GeneProduct449565 (Entrez Gene)
IL4RGeneProduct454005 (Entrez Gene)
INPP5DGeneProduct470683 (Entrez Gene)
IRS1GeneProduct459985 (Entrez Gene)
IRS2GeneProduct452657 (Entrez Gene)
JAK1GeneProduct743373 (Entrez Gene)
JAK2GeneProduct464979 (Entrez Gene)
JAK3GeneProduct455848 (Entrez Gene)
LCKGeneProduct
MAPK11GeneProduct
MAPK14GeneProduct450161 (Entrez Gene)
MAPK1GeneProduct458680 (Entrez Gene)
MAPK3GeneProduct454037 (Entrez Gene)
NCF1GeneProduct743307 (Entrez Gene)
NFKB1GeneProduct461406 (Entrez Gene)
PAWRGeneProduct452094 (Entrez Gene)
PIK3CAGeneProduct460858 (Entrez Gene)
PIK3CDGeneProduct457922 (Entrez Gene)
PIK3R1GeneProduct461836 (Entrez Gene)
PIK3R2GeneProduct455855 (Entrez Gene)
PLCG1GeneProduct458253 (Entrez Gene)
PRKCDGeneProduct
PRKCIGeneProduct450143 (Entrez Gene)
PRKCZGeneProduct743533 (Entrez Gene)
PRKD3GeneProduct459158 (Entrez Gene)
PTK2GeneProduct464422 (Entrez Gene)
PTPN11GeneProduct748225 (Entrez Gene)
PTPN6GeneProduct748032 (Entrez Gene)
RASA1GeneProduct461762 (Entrez Gene)
RELAGeneProduct466665 (Entrez Gene)
RPS6KB1GeneProduct468426 (Entrez Gene)
SHC1GeneProduct457351 (Entrez Gene)
SOCS1GeneProduct737070 (Entrez Gene)
SOCS3GeneProduct454921 (Entrez Gene)
SOCS5GeneProduct459209 (Entrez Gene)
SOS1GeneProduct459171 (Entrez Gene)
SPI1GeneProduct
SRCGeneProduct458229 (Entrez Gene)
STAMGeneProduct466269 (Entrez Gene)
STAT1GeneProduct459834 (Entrez Gene)
STAT5AGeneProduct454681 (Entrez Gene)
STAT6GeneProduct452005 (Entrez Gene)
TYK2GeneProduct455703 (Entrez Gene)

Annotated Interactions

No annotated interactions
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