Ebstein-Barr virus LMP1 signaling (Sus scrofa)

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2, 4S32-PPPUUPPS32-PS36-PTES2TES1S36-PPUIKK-betaTNFIRAK1CHUKMAP3K14CCL5NFKB1MAPK1TRADDMAP3K3TRAF1SFC complexRELAp52NFKB1I-Kappa-BHSP90RELATRAF6p100CCL20IL8IFNB1I-Kappa-BRELAIKBKGMAP3K7LMP1RELANFKB1NFKB1JNKIKK-alphaRELAMAP3K7RELA1, 3


Description

based on science-slides...

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP262(r34653) with a 61% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Uemura N, Kajino T, Sanjo H, Sato S, Akira S, Matsumoto K, Ninomiya-Tsuji J; ''TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.''; J Biol Chem, 2006 PubMed Europe PMC Scholia
  2. Battaglia F, Delfino S, Merello E, Puppo M, Piva R, Varesio L, Bosco MC; ''Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB.''; J Leukoc Biol, 2008 PubMed Europe PMC Scholia
  3. Lee JS, Lee JY, Son JW, Oh JH, Shin DM, Yuk JM, Song CH, Paik TH, Jo EK; ''Expression and regulation of the CC-chemokine ligand 20 during human tuberculosis.''; Scand J Immunol, 2008 PubMed Europe PMC Scholia
  4. Song YJ, Jen KY, Soni V, Kieff E, Cahir-McFarland E; ''IL-1 receptor-associated kinase 1 is critical for latent membrane protein 1-induced p65/RelA serine 536 phosphorylation and NF-kappaB activation.''; Proc Natl Acad Sci U S A, 2006 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118088view10:46, 24 May 2021EweitzModified title
87912view12:58, 25 July 2016SusanOntology Term : 'signaling pathway' added !
68424view18:51, 5 July 2013MaintBotUpdated to 2013 gpml schema
58995view20:00, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
41923view05:03, 2 March 2011MaintBotRemoved redundant pathway information and comments
37709view19:27, 28 June 2010MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CCL20GeneProductENSSSCG00000016254 (Ensembl Pig)
CCL5GeneProductENSSSCG00000017705 (Ensembl Pig)
CHUKGeneProductENSSSCG00000010548 (Ensembl Pig)
HSP90GeneProduct
I-Kappa-BGeneProduct
IFNB1GeneProductENSSSCG00000005163 (Ensembl Pig)
IKBKGGeneProductENSSSCG00000012825 (Ensembl Pig)
IKK-alphaGeneProduct
IKK-betaGeneProduct
IL8GeneProductENSSSCG00000008953 (Ensembl Pig)
IRAK1GeneProduct
JNKGeneProduct
LMP1GeneProduct
MAP3K14GeneProductENSSSCG00000017330 (Ensembl Pig)
MAP3K3GeneProductENSSSCG00000017292 (Ensembl Pig)
MAP3K7GeneProductENSSSCG00000004334 (Ensembl Pig)
MAPK1GeneProductENSSSCG00000010081 (Ensembl Pig)
NFKB1GeneProductENSSSCG00000009168 (Ensembl Pig)
RELAGeneProductENSSSCG00000012981 (Ensembl Pig)
SFC complexGeneProduct
TNFGeneProduct
TRADDGeneProduct
TRAF1GeneProductENSSSCG00000005511 (Ensembl Pig)
TRAF6GeneProduct
p100GeneProduct
p52GeneProduct

Annotated Interactions

No annotated interactions
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