Integrated cancer pathway (Homo sapiens)

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Revision as of 23:20, 19 March 2011 by Saibrahi (Talk | contribs)
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BASC ComlexSTAT1_HUMANBARD1P53_HUMANp13KCASP9NBS1PUMAPTEN_HUMANBCL2p21Swi/SNFE2F1p14SMAD2BRCA1_HUMANCDK4CDK2MYCMSH2BRCA1CASP8BADp27BAXCASP3BACH1CHK2_HUMANBLMATM_HUMANATR_HUMANMDM2_HUMANNOXAMRE11MSH6DNA-PKOCT1Plk1AKT1_HUMANRad50CHK1_HUMANp38JAK1RbCDC25ACctlpCDC2ASK1SMAD3CDC25BMMPp15ATF1


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Wang C, Bian Z, Wei D, Zhang JG; ''miR-29b regulates migration of human breast cancer cells.''; Mol Cell Biochem, 2011 PubMed Europe PMC Scholia
  2. Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, Linsley PS, Krichevsky AM; ''MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators.''; Mol Cell Biol, 2008 PubMed Europe PMC Scholia
  3. Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T; ''MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.''; Gastroenterology, 2007 PubMed Europe PMC Scholia
  4. Zhao JJ, Lin J, Lwin T, Yang H, Guo J, Kong W, Dessureault S, Moscinski LC, Rezania D, Dalton WS, Sotomayor E, Tao J, Cheng JQ; ''microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma.''; Blood, 2010 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
126414view20:17, 26 April 2023EgonwLicense is CCZero
117762view13:24, 22 May 2021EweitzModified title
106620view20:47, 12 September 2019KhanspersModified description
105629view05:02, 10 August 2019KhanspersModified description
103003view15:02, 31 January 2019Marvin M2Updated miRNA Ensembl IDs
98351view05:22, 24 August 2018EgonwUpdated the MIR21 identifier.
96025view15:33, 15 February 2018MkutmonModified description
82939view08:51, 14 November 2015EgonwUpdated Ensembl identifiers.
82938view08:31, 14 November 2015EgonwFixed a small topy in a comment.
82936view22:43, 13 November 2015AlexanderPicoModified title
80447view06:15, 23 June 2015KhanspersAdded mir29 targeting to PTEN
80431view20:03, 22 June 2015KhanspersAdded mir21 targeting of CDC25A
80425view18:50, 22 June 2015KhanspersAdded mi21 targeting, cleaned up layout, connected lines and added some xrefs
71249view20:29, 16 October 2013MaintBotAutomated update of data sources
67398view10:56, 26 June 2013DdiglesOntology Term : 'cancer pathway' added !
63221view21:01, 8 May 2013MaintBotUpdating gpml version
59118view22:27, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
44858view09:54, 6 October 2011MartijnVanIerselOntology Term : 'cancer' added !
44469view20:30, 14 September 2011MaintBotAdded category
42356view23:30, 19 March 2011SaibrahiSpecify description
42355view23:20, 19 March 2011SaibrahiPeriodical save, work in progress
42354view22:22, 19 March 2011SaibrahiSpecify description
42262view21:45, 11 March 2011AlexanderPicoConnected BRCA1 to database
42257view14:35, 11 March 2011SaibrahiSpecify description
42256view14:31, 11 March 2011SaibrahiPeriodical save, work in progress
41986view11:44, 4 March 2011SaibrahiSpecify description
41985view11:36, 4 March 2011SaibrahiPeriodical save, work in progress
41984view11:26, 4 March 2011SaibrahiPeriodical save, work in progress
41976view02:50, 4 March 2011SaibrahiPeriodical save, work in progress
41975view02:48, 4 March 2011SaibrahiSpecify description
41076view23:20, 1 March 2011MaintBotRemoved redundant pathway information and comments
40454view17:45, 1 March 2011SaibrahiPeriodical save, work in progress
40442view20:41, 25 February 2011SaibrahiPeriodical save, work in progress
40439view15:07, 25 February 2011SaibrahiSpecify description
40438view14:57, 25 February 2011SaibrahiPeriodical save, work in progress
40437view14:55, 25 February 2011SaibrahiSpecify description
40436view14:47, 25 February 2011SaibrahiPeriodical save, work in progress
40435view14:37, 25 February 2011SaibrahiPeriodical save, work in progress
40432view14:26, 25 February 2011SaibrahiSpecify description
40430view11:26, 25 February 2011SaibrahiNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1_HUMANProteinP31749 (Uniprot/TrEMBL)
ASK1Protein
ATF1Protein
ATM_HUMANProteinQ13315 (Uniprot/TrEMBL)
ATR_HUMANProteinQ13535 (Uniprot/TrEMBL)
BACH1Protein
BADProtein
BARD1Protein
BAXProtein
BCL2Protein
BLMProtein
BRCA1Protein
BRCA1_HUMANProteinP38398 (Uniprot/TrEMBL) Phosphorylated
CASP3Protein
CASP8Protein
CASP9Protein
CDC2ProteinOncogene
CDC25AGeneProductENSG00000164045 (Ensembl Human)
CDC25BGeneProductENSG00000101224 (Ensembl Human)
CDK2Protein
CDK4Protein
CHK1_HUMANProteinO14757 (Uniprot/TrEMBL)
CHK2_HUMANProteinO96017 (Uniprot/TrEMBL) Phosphrylated
CctlpProtein
DNA-PKMetabolite
E2F1Protein
JAK1Protein
MDM2_HUMANProteinQ00987 (Uniprot/TrEMBL) Oncogene
MMPProtein
MRE11Protein
MSH2Protein
MSH6Protein
MYCProtein
NBS1Protein
NOXAProtein
OCT1Protein
P53_HUMANProteinP04637 (Uniprot/TrEMBL)
PTEN_HUMANProteinP60484 (Uniprot/TrEMBL)
PUMAProtein
Plk1Protein
Rad50Protein
RbProtein
SMAD2ProteinTumor supressor
SMAD3Protein
STAT1_HUMANProteinP42224 (Uniprot/TrEMBL)
Swi/SNFProtein
p13KProtein
p14Protein
p15Protein
p21Protein
p27Protein
p38Protein

Annotated Interactions

No annotated interactions

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