Angiogenesis overview (Homo sapiens)
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MT1-MMP
Dok-R
VEGF
TK
Ca2+
GF
PHD
FAK
Cdc42
Shb
Tie2
MEKK
Nox4
ROS
eloC
P110
transcription of angiogenesis-related genes
Proteosome
DAG
P85-PI3K
MT-MMP
FGF
Pak
Integrins
Grb2
Pla2
Thrombin
Ras
NO
Elk1
PLC-gamma
Raf
Ras GAP
Ca2+ - release
SEK
PLD
BAD
FGFR1
VEGFR2
IP2
APC
MMP12
Breakdown of extracellular
tissue like collagen
MEK
Crk
OH
Protein
MEK
ATF2
Nck
Shc
Migration
DAG
TIMP2
IP3
IQGAP
eNOS
Angiogenesis
VHL
Src
hypoxia
MMPs
Survival
p38 MAPK
PKC
urokinase-plasminogen activator
PDKs
PIP2
Migration
Raf
1/2 ERK MAPK
STAT5
JNK
Permeability
Ras
Sos
Grb2
PKC
Bmx
FRS-2
Shp2
MMP2
FAK
Crk
Proliferation
NADPH oxidase 2
ERK 1/2 MAPK
Dia1
Ras
MKK3/6
PI3K
STAT3
PLC-gamma
Akt / PKB
Survival
Ang1
SHP-2
AKT
Grb14
PIP2
PIP3
TIMP4
Tor
Paxillin
HIF2-alpha
p38 MAPK
HIF2-alpha
HIF2-alpha
OH
pUb
eloB
Grb2
Sos
Grb7
Description
No description
Comments
GF
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Quality Tags
Ontology Terms
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Bibliography
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History
View all...
Compare
Revision
Action
Time
User
Comment
126081
view
09:00, 1 April 2023
Egonw
Removed unclear "GF" comment
126080
view
08:50, 1 April 2023
Egonw
Added a few datanode types (guessed a few, because no IDs were given)
110975
view
14:21, 25 June 2020
L Dupuis
Connected lines
106214
view
12:11, 16 August 2019
MaintBot
HMDB identifier normalization
85555
view
08:32, 29 May 2016
Egonw
Replaced a mim-conversion with Arrow.
71385
view
18:41, 17 October 2013
MaintBot
Automated update of data sources
71268
view
21:58, 16 October 2013
MaintBot
Automated update of data sources
69001
view
17:45, 8 July 2013
MaintBot
Updated to 2013 gpml schema
59192
view
19:07, 22 February 2013
MaintBot
Updated Ensembl and UniProt data source
58505
view
19:00, 14 February 2013
MaintBot
Modified title
44954
view
12:37, 6 October 2011
MartijnVanIersel
Ontology Term : 'growth factor signaling pathway' added !
44820
view
13:30, 5 October 2011
Susan
Modified description
44464
view
18:42, 14 September 2011
MaintBot
Modified categories
44462
view
14:33, 14 September 2011
Helix
angiogenesis overview
44393
view
10:35, 8 September 2011
Helix
angiogenesis overviuew
44392
view
10:26, 8 September 2011
Helix
Periodical save, work in progress
44389
view
10:15, 8 September 2011
Helix
Periodical save, work in progress
43912
view
12:37, 16 August 2011
Helix
angiogensisi overview
43911
view
12:29, 16 August 2011
Helix
Periodical save, work in progress
43909
view
12:19, 16 August 2011
Helix
Periodical save, work in progress
43908
view
11:54, 16 August 2011
Helix
Periodical save, work in progress
43907
view
11:43, 16 August 2011
Helix
Periodical save, work in progress
43906
view
11:31, 16 August 2011
Helix
angiogenesis overview
43905
view
11:11, 16 August 2011
Helix
Periodical save, work in progress
43902
view
11:48, 15 August 2011
Helix
angiogenesis overview
43901
view
11:46, 15 August 2011
Helix
Periodical save, work in progress
43900
view
11:36, 15 August 2011
Helix
Periodical save, work in progress
43899
view
11:26, 15 August 2011
Helix
Periodical save, work in progress
43898
view
11:15, 15 August 2011
Helix
Periodical save, work in progress
43896
view
11:04, 15 August 2011
Helix
angiogenesis overview
43605
view
09:00, 7 July 2011
Helix
angiopgenesis overview
43604
view
08:57, 7 July 2011
Helix
Periodical save, work in progress
43603
view
08:46, 7 July 2011
Helix
Periodical save, work in progress
43602
view
08:36, 7 July 2011
Helix
Periodical save, work in progress
43596
view
09:28, 6 July 2011
Helix
angiogenesis overview
43146
view
13:05, 3 June 2011
Helix
angiogenesis overview
43145
view
12:58, 3 June 2011
Helix
Periodical save, work in progress
43144
view
12:48, 3 June 2011
Helix
Periodical save, work in progress
43143
view
12:37, 3 June 2011
Helix
Periodical save, work in progress
43142
view
12:27, 3 June 2011
Helix
Periodical save, work in progress
43141
view
12:17, 3 June 2011
Helix
Periodical save, work in progress
43140
view
11:38, 3 June 2011
Helix
Periodical save, work in progress
43139
view
11:28, 3 June 2011
Helix
Periodical save, work in progress
43138
view
11:17, 3 June 2011
Helix
Periodical save, work in progress
43137
view
11:07, 3 June 2011
Helix
Periodical save, work in progress
43136
view
10:43, 3 June 2011
Helix
Periodical save, work in progress
43135
view
10:40, 3 June 2011
Helix
angiogenesis overview
43134
view
10:33, 3 June 2011
Helix
Periodical save, work in progress
43133
view
10:23, 3 June 2011
Helix
Periodical save, work in progress
43132
view
10:13, 3 June 2011
Helix
Periodical save, work in progress
External references
DataNodes
View all...
Name
Type
Database reference
Comment
1/2 ERK MAPK
Protein
AKT
Protein
APC
Protein
ATF2
Protein
Akt / PKB
Protein
Ang1
Protein
Angiogenesis
Pathway
BAD
Protein
Bmx
Protein
Breakdown of extracellular tissue like collagen
Pathway
Ca2+ - release
Pathway
Crk
Protein
DAG
Protein
Dia1
Protein
ERK 1/2 MAPK
Protein
Elk1
Protein
FAK
Protein
FGFR1
Protein
FRS-2
Protein
Grb14
Protein
Grb2
Protein
Grb7
Protein
HIF2-alpha
Protein
IP2
Protein
IP3
Protein
IQGAP
Protein
JNK
Protein
MEK
Protein
MKK3/6
Protein
MMP12
Protein
MMP2
Protein
MMPs
Protein
Migration
Pathway
NADPH oxidase 2
Protein
NO
Protein
Nck
Protein
OH
PDKs
Protein
PI3K
Protein
PIP2
Protein
PIP3
Protein
PKC
Protein
PLC-gamma
Protein
PLD
Protein
Paxillin
Protein
Permeability
Pathway
Pla2
Protein
Proliferation
Pathway
Protein
Protein
Raf
Protein
Ras
Protein
Ras GAP
Protein
SEK
Protein
SHP-2
Protein
STAT3
Protein
STAT5
Protein
Shc
Protein
Shp2
Protein
Sos
Protein
Src
Protein
Survival
Pathway
TIMP2
Protein
TIMP4
Protein
Thrombin
Protein
Tor
Protein
VEGFR2
VHL
Protein
eNOS
Protein
hypoxia
p38 MAPK
Protein
p38 MAPK
pUb
urokinase-plasminogen activator
Protein
Annotated Interactions
No annotated interactions
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Pathway
Discussion
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