TSH signaling pathway (Homo sapiens)

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CCND3CCND3MAP2K1PMAPK3PPIK3R2PKADAGIP3PIP3PIP2cAMPProtein - protein dissociationEnzyme ComplexLigandCell proliferationmRNAProteinCYNUProteinTSH Signaling PathwayReceptorProteinE2F1PAX8STAT1 GNG2SCRIBRAF1GNB1HRASEGR1TSHBTTF2KCNIP3CGATTF1JUNMYCFOSBRAFGTPPTSHRSTAT3PPDPK1PPIK3CAPIK3R1CDK2PPSRCpMAP2K3PMAP2K6AKT1PPPRKCZRPS6KB1MAPK1PPRB1PCREB1PDE4DPPGNAI1GNA13GTPGNAI2GTPGNA12GTPGTPGNAO1GTPGNAQGTPGNAI3GTPMYL12BDePRALGDSGNASGTPJAK2JAK1PPRPS6MTORPADCY2ADCY3CDK2PCDK4PRPS6KA1PPLD1PLCB1RAP1BGTPRAP1AGTPRHOACCNE1MAPK14CDKN1BPCCND3CDK4RAP1GAPPPNUCYPKANUCYSmall moleculeInduced activationInhibitionAuto catalysisTransportPositive regulation of gene expressionLeads to through unknown mechanismNegative regulation of gene expressionTranslocation UbiquitinationDeubiquitinationSumoylationInduced catalysisProtein-protein interactionAcetylationDephosphorylationLEGENDPhosphorylationDeacetylationGolgi apparatusEndosomeNucleusMitochondrionDesumoylationMethylationDemethylationPalmitoylationCytoplasmECPlasma membraneMTEndoplasmic reticulumCYPMGONUExtracellularERENProteolytic cleavageMoleculeAPEX1APEX1NUCY


Description

No description

Comments

GenMAPP notes 
NetPath_23 - TSH signaling pathway. NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org

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Bibliography


History

CompareRevisionActionTimeUserComment
44636view18:25, 22 September 2011KhanspersDeleted pathway: duplicate
44557view08:35, 20 September 2011JyotiModified description
44556view08:26, 20 September 2011JyotiNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADCY2Protein108 (Entrez Gene)
ADCY3Protein109 (Entrez Gene)
AKT1Protein207 (Entrez Gene)
APEX1Protein328 (Entrez Gene)
BRAFProtein673 (Entrez Gene)
CCND3Protein896 (Entrez Gene)
CCNE1Protein898 (Entrez Gene)
CDK2Protein1017 (Entrez Gene)
CDK4Protein1019 (Entrez Gene)
CDKN1BProtein1027 (Entrez Gene)
CGAProtein1081 (Entrez Gene)
CREB1Protein1385 (Entrez Gene)
E2F1Rna1869 (Entrez Gene)
EGR1Rna1958
FOSRna2353 (Entrez Gene)
GNA12Protein2768 (Entrez Gene)
GNA13Protein10672 (Entrez Gene)
GNAI1Protein2770 (Entrez Gene)
GNAI2Protein2771 (Entrez Gene)
GNAI3Protein2773 (Entrez Gene)
GNAO1Protein2775 (Entrez Gene)
GNAQProtein2776 (Entrez Gene)
GNASProtein2778 (Entrez Gene)
GNB1Protein2782 (Entrez Gene)
GNG2Protein54331 (Entrez Gene)
HRASProtein3265 (Entrez Gene)
JAK1Protein3716 (Entrez Gene)
JAK2Protein3717 (Entrez Gene)
JUNRna3725 (Entrez Gene)
KCNIP3Protein30818 (Entrez Gene)
MAP2K1Protein5604 (Entrez Gene)
MAP2K3Protein5606 (Entrez Gene)
MAP2K6Protein5608 (Entrez Gene)
MAPK14Protein1432 (Entrez Gene)
MAPK1Protein5594 (Entrez Gene)
MAPK3Protein5595 (Entrez Gene)
MTORProtein2475 (Entrez Gene)
MYCRna
MYL12BProtein103910 (Entrez Gene)
PAX8Rna7849 (Entrez Gene)
PDE4DProtein5144 (Entrez Gene)
PDPK1Protein5170 (Entrez Gene)
PIK3CAProtein5290 (Entrez Gene)
PIK3R1Protein5295 (Entrez Gene)
PIK3R2Protein5296 (Entrez Gene)
PLCB1Protein23236 (Entrez Gene)
PLD1Protein5337 (Entrez Gene)
PRKCZProtein5934 (Entrez Gene)
RAF1Protein5894 (Entrez Gene)
RALGDSProtein5900 (Entrez Gene)
RAP1AProtein5906 (Entrez Gene)
RAP1BProtein5908 (Entrez Gene)
RAP1GAPProtein5909 (Entrez Gene)
RB1Protein5925 (Entrez Gene)
RHOAProtein3480 (Entrez Gene)
RPS6Protein6194 (Entrez Gene)
RPS6KA1Protein6195 (Entrez Gene)
RPS6KB1Protein6198 (Entrez Gene)
SCRIBProtein23513 (Entrez Gene)
SRCProtein6714 (Entrez Gene)
STAT1 Protein6772 (Entrez Gene)
STAT3Protein6774 (Entrez Gene)
TSHBProtein7252 (Entrez Gene)
TSHRProtein7253 (Entrez Gene)
TTF1Rna7270 (Entrez Gene)
TTF2Rna8458 (Entrez Gene)

Annotated Interactions

No annotated interactions
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