Alanine and aspartate metabolism (Homo sapiens)
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1, 2
Protein
Citrate cycle (TCA cycle)
Fatty acid metabolism
L-Alanyl-tRNA
6.3.2.11
6.3.5.6
b-Alanine
2.6.1.18
Reductive carboxylate
cycle (CO2 fixation)
3.5.1.1
Arginine and Proline metabolism
Selenoamino acid metabolism
GOT2
6.3.1.1
L-Alanine
L-aspartate
ASPA
L-Argininosuccinate
tRNA(Asp)
Adenylosuccinate
Malonate semialdehyde
6.1.1.22
ASS
N-Carbamoyl-L-aspartate
N-Acetyl-L-aspartate
1.4.3.16
2-Oxoglutarate
Oxaloacetate
3.5.1.38
Carnosine
GOT1
4.3.2.2
Acetyl-CoA
tRNA (Asn)
5.1.1.13
DARS
Histidine metabolism
3.4.13.3
Lysine biosynthesis
Glycine, serine and threonine metabolism
D-Ala metabolism
4.1.1.11
6.1.1.7
Pantothenate and CoA biosynthesis
AGXT
6.3.4.4
1.2.1.18
DARS
2.3.1.7
D-aspartate
4.3.1.1
Malate
4.1.1.12
2-Oxosuccinamate
Urea cycel and metabolism of amino groups
D-Alanine
beta-Alanine metabolism
L-Asparagine
O-Acetylcarnitine
2.6.1.14
Reductive carboxylate cycle (CO2 fixation)
Cyanoamino acid metabolism
2.1.3.2
L-Asparagine acid
Pyrimidine metabolism
1.4.3.2
Fumarate
PC
Citric acid
1.4.3.1
1.4.3.15
GPT
Nicotinate and nicotinamide metabolism
Glycolysis & gluconeogenesis
L-Asparagine acid
3.5.1.7
tRNA (Asn)
Pyruvate
6.3.5.4
ASL
2.6.1.12
GAD2
ABAT
Nicotinate and nicotinamide metabolism
3.5.1.3
Succinate
GAD1
5.1.1.1
L-Aspartic acid
Description
No description
Comments
GenMAPP notes
Converted from rat to human using ortholog information. Link to original KEGG map:
http://www.genome.ad.jp/dbget-bin/show
pathway?rno00252
GenMAPP remarks
Edited by Sebastien Burel.
Try the New WikiPathways
View approved pathways at
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Wu G; ''Intestinal mucosal amino acid catabolism.''; J Nutr, 1998
PubMed
Europe PMC
Scholia
Curien G, Bastien O, Robert-Genthon M, Cornish-Bowden A, Cárdenas ML, Dumas R; ''Understanding the regulation of aspartate metabolism using a model based on measured kinetic parameters.''; Mol Syst Biol, 2009
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
126966
view
21:54, 8 July 2023
Egonw
Another clickable pathway
126957
view
15:29, 7 July 2023
Ddigles
Changed ID of b-Alanine (pointed to Adrenaline), made pathway clickable.
126214
view
13:50, 16 April 2023
Egonw
License is CCZero
114258
view
13:50, 2 January 2021
Egonw
Three more pathways clickable
107574
view
05:05, 23 October 2019
Khanspers
Modified description
107573
view
05:01, 23 October 2019
Khanspers
Modified description
107115
view
14:19, 17 September 2019
MaintBot
ChEBI identifier normalization
106171
view
12:06, 16 August 2019
MaintBot
HMDB identifier normalization
105875
view
04:49, 16 August 2019
Khanspers
Modified description
105436
view
04:36, 8 August 2019
Khanspers
Modified description
105119
view
22:00, 8 July 2019
Khanspers
Modified description
102414
view
09:50, 23 December 2018
Egonw
Replaced a deleted CAS number with the active one.
94196
view
14:39, 25 August 2017
Mkutmon
added missing metabolite identifier
92993
view
18:20, 21 July 2017
Khanspers
fixed unconnected
92992
view
18:17, 21 July 2017
Khanspers
Modified description
92991
view
18:17, 21 July 2017
Khanspers
removed GenMAPP notes
92892
view
18:57, 14 July 2017
Egonw
Added a missing metabolite ID.
92891
view
18:51, 14 July 2017
Egonw
Replace a CAS number for a totally different compound with the ChEBI ID for L-alanine.
92890
view
18:51, 14 July 2017
Egonw
Added a missing metabolite ID.
91240
view
20:15, 21 January 2017
AlexanderPico
Quick edit to datanode annotation or property
89638
view
06:26, 22 September 2016
Egonw
Connected a line (the 2nd was too hard).
74147
view
11:26, 1 April 2014
Egonw
Replaced an InChI with a more traditional identifier.
71277
view
22:57, 16 October 2013
MaintBot
Updated UniProt/TrEMBL data source
67036
view
09:57, 26 June 2013
Christine Chichester
Ontology Term : 'alanine, aspartate and glutamate metabolic pathway' added !
63140
view
19:17, 8 May 2013
MaintBot
Updating GPML version
54702
view
13:23, 7 December 2012
Andra
RDF Tidy
53476
view
23:01, 7 November 2012
Andra
45055
view
19:43, 6 October 2011
AlexanderPico
added db refs for metabolites
45039
view
18:57, 6 October 2011
AlexanderPico
added EC number refs
44946
view
12:32, 6 October 2011
MartijnVanIersel
Ontology Term : 'amino acid metabolic pathway' added !
41117
view
23:37, 1 March 2011
MaintBot
Removed redundant pathway information and comments
38938
view
22:12, 24 September 2010
Khanspers
overhaul of metabolites, pathway links and connectors
38933
view
21:50, 24 September 2010
Khanspers
Periodical save, work in progress
38931
view
21:40, 24 September 2010
Khanspers
Periodical save, work in progress
38925
view
21:30, 24 September 2010
Khanspers
Periodical save, work in progress
38922
view
21:19, 24 September 2010
Khanspers
Periodical save, work in progress
38921
view
21:09, 24 September 2010
Khanspers
38826
view
10:24, 24 September 2010
MartijnVanIersel
linked pathway
38640
view
11:36, 23 September 2010
MartijnVanIersel
pathway link
35516
view
13:51, 12 February 2010
Michiel
Added ref
35424
view
10:53, 12 February 2010
Andra
Added reference
34472
view
18:34, 10 December 2009
MaintBot
Automatic update of empty xrefs
32205
view
12:40, 15 August 2009
MaintBot
Fixed text labels
31692
view
11:47, 14 August 2009
MaintBot
Fixed group labels
20905
view
11:30, 14 November 2008
MaintBot
[[Pathway:Homo sapiens:Alanine and aspartate metabolism KEGG]] moved to [[Pathway:WP106]]: Moved to stable identifier
14689
view
19:24, 23 May 2008
Khanspers
Periodical save, work in progress
14686
view
19:14, 23 May 2008
Khanspers
Periodical save, work in progress
14684
view
19:02, 23 May 2008
Khanspers
connectors
14682
view
18:57, 23 May 2008
Khanspers
connectors
14679
view
18:47, 23 May 2008
Khanspers
Periodical save, work in progress
External references
DataNodes
View all...
Name
Type
Database reference
Comment
1.2.1.18
GeneProduct
1.2.1.18 (EC Number)
1.4.3.1
GeneProduct
1.4.3.1 (EC Number)
1.4.3.15
GeneProduct
1.4.3.15 (EC Number)
1.4.3.16
GeneProduct
1.4.3.16 (EC Number)
1.4.3.2
GeneProduct
1.4.3.2 (EC Number)
2-Oxoglutarate
Metabolite
C00026 (Kegg Compound)
2-Oxosuccinamate
Metabolite
2.1.3.2
GeneProduct
2.1.3.2 (EC Number)
2.3.1.7
GeneProduct
2.3.1.7 (EC Number)
2.6.1.12
GeneProduct
2.6.1.12 (EC Number)
2.6.1.14
GeneProduct
2.6.1.14 (EC Number)
2.6.1.18
GeneProduct
2.6.1.18 (EC Number)
3.4.13.3
GeneProduct
3.4.13.3 (EC Number)
3.5.1.1
GeneProduct
3.5.1.1 (EC Number)
3.5.1.3
GeneProduct
3.5.1.3 (EC Number)
3.5.1.38
GeneProduct
3.5.1.38 (EC Number)
3.5.1.7
GeneProduct
3.5.1.7 (EC Number)
4.1.1.11
GeneProduct
4.1.1.11 (EC Number)
4.1.1.12
GeneProduct
4.1.1.12 (EC Number)
4.3.1.1
GeneProduct
4.3.1.1 (EC Number)
4.3.2.2
GeneProduct
4.3.2.2 (EC Number)
5.1.1.13
GeneProduct
5.1.1.13 (EC Number)
5.1.1.1
GeneProduct
5.1.1.1 (EC Number)
6.1.1.22
GeneProduct
6.1.1.22 (EC Number)
6.1.1.7
GeneProduct
6.1.1.7 (EC Number)
6.3.1.1
GeneProduct
6.3.1.1 (EC Number)
6.3.2.11
GeneProduct
6.3.2.11 (EC Number)
6.3.4.4
GeneProduct
6.3.4.4 (EC Number)
6.3.5.4
GeneProduct
6.3.5.4 (EC Number)
6.3.5.6
GeneProduct
6.3.5.6 (EC Number)
ABAT
GeneProduct
18 (Entrez Gene)
AGXT
GeneProduct
189 (Entrez Gene)
ASL
GeneProduct
435 (Entrez Gene)
ASPA
GeneProduct
443 (Entrez Gene)
ASS
GeneProduct
445 (Entrez Gene)
Acetyl-CoA
Metabolite
72-89-9 (CAS)
Acetyl-CoA
Adenylosuccinate
Metabolite
Arginine and Proline metabolism
Pathway
Carnosine
Metabolite
305-84-0 (CAS)
Carnosine
Citric acid
Metabolite
HMDB00094 (HMDB)
Cyanoamino acid metabolism
Pathway
D-Ala metabolism
Pathway
D-Alanine
Metabolite
338-69-2 (CAS)
D-Alanine
D-aspartate
Metabolite
C00402 (Kegg Compound)
DARS
GeneProduct
1615 (Entrez Gene)
Fatty acid metabolism
Pathway
WP143 (WikiPathways)
Fumarate
Metabolite
C00122 (Kegg Compound)
GAD1
GeneProduct
2571 (Entrez Gene)
GAD2
GeneProduct
2572 (Entrez Gene)
GOT1
GeneProduct
2805 (Entrez Gene)
GOT2
GeneProduct
2806 (Entrez Gene)
GPT
GeneProduct
2875 (Entrez Gene)
Glycine, serine and threonine metabolism
Pathway
Glycolysis & gluconeogenesis
Pathway
WP534 (WikiPathways)
Histidine metabolism
Pathway
L-Alanine
Metabolite
6912-68-1 (CAS)
L-Argininosuccinate
Metabolite
L-Asparagine acid
Metabolite
70-47-3 (CAS)
L-Asparagine
Metabolite
70-47-3 (CAS)
L-Asparagine
L-Aspartic acid
Metabolite
C00049 (Kegg Compound)
L-aspartate
Metabolite
C00049 (Kegg Compound)
Lysine biosynthesis
Pathway
Malate
Metabolite
617-48-1 (CAS)
(S)-Malate
Malonate semialdehyde
Metabolite
33190 (ChEBI)
N-Acetyl-L-aspartate
Metabolite
N-Carbamoyl-L-aspartate
Metabolite
15859 (ChEBI)
Nicotinate and nicotinamide metabolism
Pathway
O-Acetylcarnitine
Metabolite
3040-38-8 (CAS)
Oxaloacetate
Metabolite
C00036 (Kegg Compound)
PC
GeneProduct
5091 (Entrez Gene)
Pantothenate and CoA biosynthesis
Pathway
Pyrimidine metabolism
Pathway
Pyruvate
Metabolite
32816 (ChEBI)
Reductive carboxylate cycle (CO2 fixation)
Pathway
Reductive carboxylate cycle (CO2 fixation)
Pathway
Selenoamino acid metabolism
Pathway
Succinate
Metabolite
C00042 (Kegg Compound)
Urea cycel and metabolism of amino groups
Pathway
WP497
b-Alanine
Metabolite
6912-68-1 (CAS)
beta-alanine
beta-Alanine metabolism
Pathway
tRNA (Asn)
GeneProduct
tRNA(Asp)
GeneProduct
Annotated Interactions
No annotated interactions
Views
Pathway
Discussion
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View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions