metapathway biotransformation (Mus musculus)

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MethyltransferasesNucleophilesGlutathione reductaseCytochrome P450ReductionHydrolysisAldo-keto reductasesGlutathione conjugationMethylationAmino acid acyl transferasesGlucuronosyltransferasesOxidationGlutathione synthetaseSulfotransferasesN-acetyltransferasesElectrophilesSulfationEpoxide hydrolasesGlutathione transferasesGlucuronidationGlutathione peroxidasesAcetylationFlavin monooxygenasesAmino acid conjugationCYP21A2Cyp3a44Ugt2b1BaatChst10Glutathione transferaseCyp1a1Cyp8b1AKR1C3Hs6st2Chst5CYP2A7Hs3st3a1UGT2B15Substrate-SO3HCyp2c69Hs3st2GSTA2Naa40Cyp4v3SULT1A4Gpx4Naa20UGT1A1Cyp26a1Gm9994Cyp3a44Substrate-AaCyp24a1INMTUGT1A4Mgst3Sult1c2Gstt2Cyp1b1GLYATL2Cyp11a1Ndst4Aldo-keto reductaseEphx1Substrate-O-R2810007J24RikChst2Naa30Nat14Cyp1a2Substrate-SGCyp7b1UGT1A3Substrate-SHGpx3Ephx2Substrate-CH3Chst7AKR7A2Akr1b3Chst14GSTA1Hs3st4Cyp2d12Flavin monooxygenaseGstm7Kcnab1Substrate-GlCYP4F2Ugt2b1GsrAkr1b7GSTA3AKR1C1Ugt2a3Ugt2b1Sult1b1CYP4Z1UGT1A5Hs6st1Kcnab2SULT1C4CYP27C1Cyp4x1GstcdComtAkr1a4CYP11B1AKR7A3GLYATL1Nat3Cyp4f39Cyp3a44Chst13Fmo4AKR1C2NnmtHs3st1UGT1A9GSTM5Hs6st3CYP11B2Nat3Naa50Gstt2Akr1d1GSTA4Kcnab3Fmo2Gstz1Cyp2c69Cyp26b1Cyp2w1Sult1e1Ugt1a6bCyp39a1UGT2A2Chst8Nat9Gsto2GPX5Hs3st3a1CYP2A6Gsto1GlucuronosyltransferaseCyp2j8Cyp2u1CYP4F11N-acetyltransferaseGPX1UGT2A1Substrate-OHSulfotransferaseSult2b1CYP4F3Fmo5Chst5Gstm4Ugt2b1Cyp26c1AKR1C4SULT1A3NAT6Cyp17a1HS3ST5HnmtNdst1Cyp19a1Hs2st1UGT1A7GssGal3st1Chst3CYP4F8Fmo3Nat10Gstm5MethyltransferaseUGT1A6Chst11Gstt1Xenobiotic substrateGpx2Sult4a1Cyp27a1Cyp27b1Cml2Cyp2s1TpmtGal3st4CYP2A13SULT1A1Cyp3a44Cyp2c69Cyp2b13SULT1C2Substrate=OCyp20a1CYP450GSTM1Cyp2e1CU041227.1UGT1A10Gal3st3Sult6b1Cyp7a1Mgst2Gstk1GlyatNdst3Chst4CYP4F12Nat8lAmino acid acyltransferaseChst9Cyp2c55Ndst2Cyp2f2Substrate-AcGSTA5Chst1Cyp2r1Fmo1Cyp4b1SULT1A2Chst12Hs3st6Ugt2b1Cyp46a1Gstp2Cyp51Mgst1Substrate-NH2


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP702(r44905) with a 70% conversion rate.

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Bibliography


History

CompareRevisionActionTimeUserComment
47767view05:23, 6 April 2012KhanspersDeleted pathway: duplicate
45980view21:00, 1 December 2011MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2810007J24RikGeneProductENSMUSG00000030378 (Ensembl Mouse)
AKR1C1GeneProduct
AKR1C2GeneProduct
AKR1C3GeneProduct
AKR1C4GeneProduct
AKR7A2GeneProduct
AKR7A3GeneProduct
Akr1a4GeneProductENSMUSG00000028692 (Ensembl Mouse)
Akr1b3GeneProductENSMUSG00000001642 (Ensembl Mouse)
Akr1b7GeneProductENSMUSG00000052131 (Ensembl Mouse)
Akr1d1GeneProductENSMUSG00000038641 (Ensembl Mouse)
Aldo-keto reductaseGeneProduct
Amino acid acyltransferaseGeneProduct
BaatGeneProductENSMUSG00000039653 (Ensembl Mouse)
CU041227.1GeneProductENSMUSG00000079135 (Ensembl Mouse)
CYP11B1GeneProduct
CYP11B2GeneProduct
CYP21A2GeneProduct
CYP27C1GeneProduct
CYP2A13GeneProduct
CYP2A6GeneProduct
CYP2A7GeneProduct
CYP450GeneProduct
CYP4F11GeneProduct
CYP4F12GeneProduct
CYP4F2GeneProduct
CYP4F3GeneProduct
CYP4F8GeneProduct
CYP4Z1GeneProduct
Chst10GeneProductENSMUSG00000026080 (Ensembl Mouse)
Chst11GeneProductENSMUSG00000034612 (Ensembl Mouse)
Chst12GeneProductENSMUSG00000036599 (Ensembl Mouse)
Chst13GeneProductENSMUSG00000056643 (Ensembl Mouse)
Chst14GeneProduct72136 (Entrez Gene)
Chst1GeneProductENSMUSG00000027221 (Ensembl Mouse)
Chst2GeneProductENSMUSG00000033350 (Ensembl Mouse)
Chst3GeneProductENSMUSG00000057337 (Ensembl Mouse)
Chst4GeneProductENSMUSG00000035930 (Ensembl Mouse)
Chst5GeneProductENSMUSG00000031952 (Ensembl Mouse)
Chst7GeneProductENSMUSG00000037347 (Ensembl Mouse)
Chst8GeneProductENSMUSG00000060402 (Ensembl Mouse)
Chst9GeneProduct71367 (Entrez Gene)
Cml2GeneProductENSMUSG00000033634 (Ensembl Mouse)
ComtGeneProductENSMUSG00000000326 (Ensembl Mouse)
Cyp11a1GeneProductENSMUSG00000032323 (Ensembl Mouse)
Cyp17a1GeneProductENSMUSG00000003555 (Ensembl Mouse)
Cyp19a1GeneProductENSMUSG00000032274 (Ensembl Mouse)
Cyp1a1GeneProductENSMUSG00000032315 (Ensembl Mouse)
Cyp1a2GeneProductENSMUSG00000032310 (Ensembl Mouse)
Cyp1b1GeneProductENSMUSG00000024087 (Ensembl Mouse)
Cyp20a1GeneProductENSMUSG00000049439 (Ensembl Mouse)
Cyp24a1GeneProductENSMUSG00000038567 (Ensembl Mouse)
Cyp26a1GeneProductENSMUSG00000024987 (Ensembl Mouse)
Cyp26b1GeneProductENSMUSG00000063415 (Ensembl Mouse)
Cyp26c1GeneProductENSMUSG00000062432 (Ensembl Mouse)
Cyp27a1GeneProductENSMUSG00000026170 (Ensembl Mouse)
Cyp27b1GeneProductENSMUSG00000006724 (Ensembl Mouse)
Cyp2b13GeneProductENSMUSG00000040583 (Ensembl Mouse)
Cyp2c55GeneProductENSMUSG00000025002 (Ensembl Mouse)
Cyp2c69GeneProductENSMUSG00000092008 (Ensembl Mouse)
Cyp2d12GeneProductENSMUSG00000057138 (Ensembl Mouse)
Cyp2e1GeneProductENSMUSG00000025479 (Ensembl Mouse)
Cyp2f2GeneProductENSMUSG00000052974 (Ensembl Mouse)
Cyp2j8GeneProductENSMUSG00000082932 (Ensembl Mouse)
Cyp2r1GeneProductENSMUSG00000030670 (Ensembl Mouse)
Cyp2s1GeneProductENSMUSG00000040703 (Ensembl Mouse)
Cyp2u1GeneProductENSMUSG00000027983 (Ensembl Mouse)
Cyp2w1GeneProductENSMUSG00000029541 (Ensembl Mouse)
Cyp39a1GeneProductENSMUSG00000023963 (Ensembl Mouse)
Cyp3a44GeneProductENSMUSG00000054417 (Ensembl Mouse)
Cyp46a1GeneProductENSMUSG00000021259 (Ensembl Mouse)
Cyp4b1GeneProductENSMUSG00000028713 (Ensembl Mouse)
Cyp4f39GeneProductENSMUSG00000061126 (Ensembl Mouse)
Cyp4v3GeneProductENSMUSG00000079057 (Ensembl Mouse)
Cyp4x1GeneProductENSMUSG00000047155 (Ensembl Mouse)
Cyp51GeneProductENSMUSG00000001467 (Ensembl Mouse)
Cyp7a1GeneProductENSMUSG00000028240 (Ensembl Mouse)
Cyp7b1GeneProductENSMUSG00000039519 (Ensembl Mouse)
Cyp8b1GeneProductENSMUSG00000050445 (Ensembl Mouse)
Ephx1GeneProductENSMUSG00000038776 (Ensembl Mouse)
Ephx2GeneProductENSMUSG00000022040 (Ensembl Mouse)
Flavin monooxygenaseGeneProduct
Fmo1GeneProductENSMUSG00000040181 (Ensembl Mouse)
Fmo2GeneProductENSMUSG00000040170 (Ensembl Mouse)
Fmo3GeneProductENSMUSG00000026691 (Ensembl Mouse)
Fmo4GeneProductENSMUSG00000026692 (Ensembl Mouse)
Fmo5GeneProductENSMUSG00000028088 (Ensembl Mouse)
GLYATL1GeneProduct
GLYATL2GeneProduct
GPX1GeneProduct
GPX5GeneProduct
GSTA1GeneProduct
GSTA2GeneProduct
GSTA3GeneProduct
GSTA4GeneProduct
GSTA5GeneProduct
GSTM1GeneProduct
GSTM5GeneProduct
Gal3st1GeneProductENSMUSG00000049721 (Ensembl Mouse)
Gal3st3GeneProductENSMUSG00000047658 (Ensembl Mouse)
Gal3st4GeneProductENSMUSG00000075593 (Ensembl Mouse)
GlucuronosyltransferaseGeneProduct
Glutathione transferaseGeneProduct
GlyatGeneProductENSMUSG00000063683 (Ensembl Mouse)
Gm9994GeneProductENSMUSG00000056307 (Ensembl Mouse)
Gpx2GeneProductENSMUSG00000042808 (Ensembl Mouse)
Gpx3GeneProductENSMUSG00000018339 (Ensembl Mouse)
Gpx4GeneProductENSMUSG00000075706 (Ensembl Mouse)
GsrGeneProductENSMUSG00000031584 (Ensembl Mouse)
GssGeneProductENSMUSG00000027610 (Ensembl Mouse)
GstcdGeneProductENSMUSG00000028018 (Ensembl Mouse)
Gstk1GeneProductENSMUSG00000029864 (Ensembl Mouse)
Gstm4GeneProductENSMUSG00000027890 (Ensembl Mouse)
Gstm5GeneProductENSMUSG00000004032 (Ensembl Mouse)
Gstm7GeneProductENSMUSG00000004035 (Ensembl Mouse)
Gsto1GeneProductENSMUSG00000025068 (Ensembl Mouse)
Gsto2GeneProductENSMUSG00000025069 (Ensembl Mouse)
Gstp2GeneProductENSMUSG00000038155 (Ensembl Mouse)
Gstt1GeneProductENSMUSG00000001663 (Ensembl Mouse)
Gstt2GeneProductENSMUSG00000033318 (Ensembl Mouse)
Gstz1GeneProductENSMUSG00000021033 (Ensembl Mouse)
HS3ST5GeneProduct
HnmtGeneProductENSMUSG00000026986 (Ensembl Mouse)
Hs2st1GeneProductENSMUSG00000040151 (Ensembl Mouse)
Hs3st1GeneProductENSMUSG00000051022 (Ensembl Mouse)
Hs3st2GeneProductENSMUSG00000046321 (Ensembl Mouse)
Hs3st3a1GeneProductENSMUSG00000047759 (Ensembl Mouse)
Hs3st4GeneProductENSMUSG00000078591 (Ensembl Mouse)
Hs3st6GeneProductENSMUSG00000039628 (Ensembl Mouse)
Hs6st1GeneProductENSMUSG00000045216 (Ensembl Mouse)
Hs6st2GeneProductENSMUSG00000062184 (Ensembl Mouse)
Hs6st3GeneProductENSMUSG00000053465 (Ensembl Mouse)
INMTGeneProduct
Kcnab1GeneProductENSMUSG00000027827 (Ensembl Mouse)
Kcnab2GeneProductENSMUSG00000028931 (Ensembl Mouse)
Kcnab3GeneProductENSMUSG00000018470 (Ensembl Mouse)
MethyltransferaseGeneProduct
Mgst1GeneProductENSMUSG00000008540 (Ensembl Mouse)
Mgst2GeneProductENSMUSG00000074604 (Ensembl Mouse)
Mgst3GeneProductENSMUSG00000026688 (Ensembl Mouse)
N-acetyltransferaseGeneProduct
NAT6GeneProduct
Naa20GeneProductENSMUSG00000002728 (Ensembl Mouse)
Naa30GeneProductENSMUSG00000036282 (Ensembl Mouse)
Naa40GeneProductENSMUSG00000024764 (Ensembl Mouse)
Naa50GeneProductENSMUSG00000022698 (Ensembl Mouse)
Nat10GeneProductENSMUSG00000027185 (Ensembl Mouse)
Nat14GeneProductENSMUSG00000035285 (Ensembl Mouse)
Nat3GeneProductENSMUSG00000056426 (Ensembl Mouse)
Nat8lGeneProductENSMUSG00000048142 (Ensembl Mouse)
Nat9GeneProductENSMUSG00000015542 (Ensembl Mouse)
Ndst1GeneProductENSMUSG00000054008 (Ensembl Mouse)
Ndst2GeneProductENSMUSG00000039308 (Ensembl Mouse)
Ndst3GeneProductENSMUSG00000027977 (Ensembl Mouse)
Ndst4GeneProductENSMUSG00000027971 (Ensembl Mouse)
NnmtGeneProductENSMUSG00000032271 (Ensembl Mouse)
SULT1A1GeneProduct
SULT1A2GeneProduct
SULT1A3GeneProduct
SULT1A4GeneProduct
SULT1C2GeneProduct
SULT1C4GeneProduct
Substrate-AaMetabolite
Substrate-AcMetabolite
Substrate-CH3Metabolite
Substrate-GlMetabolite
Substrate-NH2Metabolite
Substrate-O-RMetabolite
Substrate-OHMetabolite
Substrate-SGMetabolite
Substrate-SHMetabolite
Substrate-SO3HMetabolite
Substrate=OMetabolite
SulfotransferaseGeneProduct
Sult1b1GeneProductENSMUSG00000029269 (Ensembl Mouse)
Sult1c2GeneProductENSMUSG00000023122 (Ensembl Mouse)
Sult1e1GeneProductENSMUSG00000029272 (Ensembl Mouse)
Sult2b1GeneProductENSMUSG00000003271 (Ensembl Mouse)
Sult4a1GeneProductENSMUSG00000018865 (Ensembl Mouse)
Sult6b1GeneProductENSMUSG00000038045 (Ensembl Mouse)
TpmtGeneProductENSMUSG00000021376 (Ensembl Mouse)
UGT1A1GeneProduct
UGT1A10GeneProduct
UGT1A3GeneProduct
UGT1A4GeneProduct
UGT1A5GeneProduct
UGT1A6GeneProduct
UGT1A7GeneProduct
UGT1A9GeneProduct
UGT2A1GeneProduct
UGT2A2GeneProduct
UGT2B15GeneProduct
Ugt1a6bGeneProductENSMUSG00000090145 (Ensembl Mouse)
Ugt2a3GeneProductENSMUSG00000035780 (Ensembl Mouse)
Ugt2b1GeneProductENSMUSG00000035836 (Ensembl Mouse)
Xenobiotic substrateMetabolite

Annotated Interactions

No annotated interactions
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