SREBF and miR33 in cholesterol and lipid homeostasis (Mus musculus)

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Bibliography

1. Gerin I, Clerbaux LA, Haumont O, Lanthier N, Das AK, Burant CF, Leclercq IA, MacDougald OA, Bommer GT; ''Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation.''; J Biol Chem, 2010 PubMed Europe PMC Scholia
2. Rodgers JT, Puigserver P; ''Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1.''; Proc Natl Acad Sci U S A, 2007 PubMed Europe PMC Scholia
3. Horie T, Ono K, Horiguchi M, Nishi H, Nakamura T, Nagao K, Kinoshita M, Kuwabara Y, Marusawa H, Iwanaga Y, Hasegawa K, Yokode M, Kimura T, Kita T; ''MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo.''; Proc Natl Acad Sci U S A, 2010 PubMed Europe PMC Scholia
4. Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH; ''SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.''; EMBO J, 2007 PubMed Europe PMC Scholia
5. Yang F, Vought BW, Satterlee JS, Walker AK, Jim Sun ZY, Watts JL, DeBeaumont R, Saito RM, Hyberts SG, Yang S, Macol C, Iyer L, Tjian R, van den Heuvel S, Hart AC, Wagner G, Näär AM; ''An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.''; Nature, 2006 PubMed Europe PMC Scholia
6. Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, Puigserver P; ''mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.''; Nature, 2007 PubMed Europe PMC Scholia
7. Walker AK, Yang F, Jiang K, Ji JY, Watts JL, Purushotham A, Boss O, Hirsch ML, Ribich S, Smith JJ, Israelian K, Westphal CH, Rodgers JT, Shioda T, Elson SL, Mulligan P, Najafi-Shoushtari H, Black JC, Thakur JK, Kadyk LC, Whetstine JR, Mostoslavsky R, Puigserver P, Li X, Dyson NJ, Hart AC, Näär AM; ''Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP.''; Genes Dev, 2010 PubMed Europe PMC Scholia
8. Joseph T Rodgers, Pere Puigserver; ''Receptor feasts on sugar and cholesterol''; Nature Medicine, 2007 PubMed Europe PMC Scholia
9. Gerhart-Hines Z, Rodgers JT, Bare O, Lerin C, Kim SH, Mostoslavsky R, Alt FW, Wu Z, Puigserver P; ''Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha.''; EMBO J, 2007 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
ABCA1	GeneProduct
FASN	GeneProduct
Hmgcr	GeneProduct	ENSMUSG00000021670 (Ensembl Mouse)
Hmgcs1	GeneProduct	ENSMUSG00000079301 (Ensembl Mouse)
Ldlr	GeneProduct	ENSMUSG00000032193 (Ensembl Mouse)
MIR33B	GeneProduct
Med15	GeneProduct	ENSMUSG00000012114 (Ensembl Mouse)
Mir33	GeneProduct	ENSMUSG00000065465 (Ensembl Mouse)
Mtor	GeneProduct	ENSMUSG00000028991 (Ensembl Mouse)
Nr1h3	GeneProduct	ENSMUSG00000002108 (Ensembl Mouse)
PRKAA1	GeneProduct
Ppara	GeneProduct	ENSMUSG00000022383 (Ensembl Mouse)
Ppargc1a	GeneProduct	ENSMUSG00000029167 (Ensembl Mouse)
SCD	GeneProduct
Sirt1	GeneProduct	ENSMUSG00000020063 (Ensembl Mouse)
Sirt6	GeneProduct	ENSMUSG00000034748 (Ensembl Mouse)
Srebf1	GeneProduct	ENSMUSG00000020538 (Ensembl Mouse)
Srebf2	GeneProduct	ENSMUSG00000022463 (Ensembl Mouse)

Annotated Interactions